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Molecular biologists develop pipeline to create and screen new lantibiotic peptides

Nature has provided us with lots of antimicrobials. However, given the rapid increase of antimicrobial resistance, there is a need for the development of new-to-nature antibiotics. Lantibiotics are an interesting option.

3 Apr 2019

New project to develop prototype diagnostic tool for early detection of Lyme disease

Unitive Design & Analysis are the sole UK contributors to a three year translational project to develop a prototype Point of Care Diagnostic tool to address the growing problem of Lyme disease.

2 Apr 2019

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV are treated with antiretroviral therapy, their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies.

2 Apr 2019

Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

New analysis establishes global microbial signatures for colorectal cancer

Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage as key players: while stomach cancer can be caused by a single bacterial species, Helicobacter pylori, the role that gut microbes play in the development of colorectal cancer - the third most common cancer worldwide - is less clear.

2 Apr 2019

Gut microbiota can help predict occurrence of colorectal cancer

Gut microbiota - the population of microbes that live in our intestine - can be used to predict the occurrence of colorectal cancer, the second most common type of cancer in women and the third in men.

1 Apr 2019

Potential target for Group A Streptococcus vaccine identified

Most people think of "strep throat" as a relatively benign infection cured by a round of antibiotics and a few days of rest. But the bacterium that causes strep throat -- Group A Streptococcus -- is also responsible for a number of much more dangerous disorders, including rheumatic heart disease and toxic shock syndrome.

1 Apr 2019

Fish slime could be a potential source of antibiotics finds study

With the advent of multi-drug resistant bacteria and lack of new antibiotics, researchers have been on the lookout for new molecules that can fight these pathogens. A team of researchers have now identified a slimy mucous coating of young fish as a potential source for antibiotics that could fight resistant infections such as MRSA (Methicillin Resistant Staphylococcus aureus).

31 Mar 2019

Seemingly identical bacteria may have a different effect

Our gut microbiome - the complement of bacteria we carry around in our intestines - has been linked to everything from obesity and diabetes to heart disease and even neurological disorders and cancer.

30 Mar 2019

UA immunobiology professor will use $1.9 million grant to study copper's therapeutic potential

Pneumonia starts like this: A bacterial cell called Streptococcus pneumoniae enters the nostril. It travels down the nasal passage and into the lungs, where a war begins. In the lungs, S. pneumoniae encounters immune cells called macrophages, which will do whatever they can to fight it off.

29 Mar 2019

Gastrointestinal symptoms in children could be a red flag for future mental health problems

A Columbia University study has found that adversity early in life is associated with increased gastrointestinal symptoms in children that may have an impact on the brain and behavior as they grow to maturity.

29 Mar 2019

Nanovaccine boosts immunity in mice with gut microbiome-mediated metabolic syndrome

A new class of biomaterial developed by Cornell researchers for an infectious disease nanovaccine effectively boosted immunity in mice with metabolic disorders linked to gut bacteria - a population that shows resistance to traditional flu and polio vaccines.

29 Mar 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Researchers identify crucial player in controlling misfolded proteins

Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal.

27 Mar 2019

Coating medical implant surfaces with microgel flecks could help reduce infection rates

Joint replacements are among the most common elective surgeries -- but around one in 100 patients suffer post-surgical infections, turning a routine procedure into an expensive and dangerous ordeal.

27 Mar 2019

Autophagy can help combat Salmonella and other pathogens

Autophagy - the process of recycling cellular material in the body, can help combat Salmonella and other pathogens according to researchers at the School of Life Sciences, University of Warwick who have studied how autophagy can get rid of bacteria, and prevent diseases developing.

27 Mar 2019