Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Thoratec to sell ITC division to Danaher

Thoratec Corporation, a world leader in device-based mechanical circulatory support therapies to save, support and restore failing hearts, said today that it has signed a definitive agreement to sell its International Technidyne Corporation (ITC) division to Danaher Corporation ( DHR).

From Danaher 26 Apr 2010

Covidien introduces PENNSAID to the U.S. market

Covidien, a leading global provider of healthcare products, has introduced PENNSAID (diclofenac sodium topical solution) 1.5% w/w to the U.S. market. PENNSAID is the only FDA-approved topical non-steroidal anti-inflammatory drug in a vehicle solution containing dimethyl sulfoxide, a known penetrating agent. It is indicated for treatment of the signs and symptoms of osteoarthritis of the knee(s).

26 Apr 2010

Beijing Customs seize Biosite's Triage products

Biosite's Triage products imported by Inverness Medical Beijing Co., Ltd. in April 2010 have been seized by Beijing Customs for not complying with the applicable importation regulations. As a result, the Chinese market is facing a severe shortage.

26 Apr 2010

Cedars-Sinai Heart Institute presents new findings on heart transplantation rejection factors

Physician scientists at the Cedars-Sinai Heart Institute are presenting new findings on heart transplantation rejection factors such as race and gender, the effects of pre-transplant smoking and whether homeless organ donors put recipients at higher risk for complications. The presentations will take place April 21 - 24 in Chicago during the 30th Annual Scientific Meeting of the International Society of Heart and Lung Transplantation.

26 Apr 2010

Serum cortisol levels linked with increased mortality in patients with ACS: Research

Growing evidence suggests that serum cortisol levels are associated with increased cardiovascular mortality in patients with chronic heart failure, research presented at this week's European Congress of Endocrinology shows.

26 Apr 2010

Physician panel to discuss issues related to Qutenza at Investor Day

NeurogesX, Inc., a biopharmaceutical company focused on developing and commercializing novel pain management therapies, announced today that Anthony DiTonno, President and CEO, and members of the NeurogesX management team, will host an Investor Day on Friday, April 30, 2010, from 8:15am-11:00am EDT in New York City

24 Apr 2010

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

Structural and functional congenital cardiovascular abnormalities present at birth are the leading source of all congenital defects encountered in live births. Nearly half a million children in the United States have structural heart problems ranging in severity from relatively simple issues, such as small holes between chambers of the heart, to very severe malformations, including complete absence of one or more chambers or valves.

24 Apr 2010

HeartWare International presents clinical trial data of Ventricular Assist System at ISHLT annual meeting

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies revolutionizing the treatment of advanced heart failure, today announced that data from its international clinical trial and commercial experience of the HeartWare® Ventricular Assist System showed a survival rate of 90 percent at six months and an actuarial survival rate of 86 percent at 12 months post implant.

24 Apr 2010

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

New data show improved outcomes, better survival rates and lower costs with the use of continuous flow mechanical circulatory support devices in patients awaiting heart transplants. Research will be presented this week during symposia at the International Society for Heart and Lung Transplantation (ISHLT) 30th Annual Meeting and Scientific Session at the Hilton Chicago.

24 Apr 2010

SuperSonic Imagine reports results of largest worldwide multicenter clinical breast study in ultrasound imaging

SuperSonic Imagine, the innovative medical imaging company based in Aix-en-Provence, France has unveiled some of the results of the largest clinical breast study ever undertaken in ultrasound imaging. The worldwide multicenter study, involving top clinicians in the breast radiology community, is assessing the clinical benefits of ShearWave™ Elastography in the ultrasonic evaluation of breast lesions.

24 Apr 2010

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Cardiola AG announced today that the Company's CE-Marked m.pulse® Muscular CounterPulsation ("MCP")-based system demonstrated "an immediate improvement of cardiac output with non-invasive means" in a patient population of advanced yet stable chronic heart failure. The effects could be shown in 22 patients over three consecutive days.

24 Apr 2010

Misonix signs exclusive distribution agreement with Suministros Medicos Multimedicas

Misonix, Inc., a developer of minimally invasive ultrasonic medical device technology, which in Europe is used for the ablation of tumors and worldwide for other acute health conditions, has entered into a new, three year, exclusive distribution agreement with Suministros Medicos Multimedicas, based in Caracas, Venezuela, for the distribution of the SonaStar Ultrasonic Surgical Aspirator, the BoneScalpel Ultrasonic Bone Cutter, and the SonicOne Ultrasonic Wound Debrider.

24 Apr 2010

Study finds no decrease in access to medical care for sicker patients needing CABG surgery

New UC Davis research has found that patients scheduled to undergo coronary artery bypass graft (CABG) surgery in California were just as ill in 2003 - when public reporting of performance data for this particular surgery began - as in 2006, evidence that "report cards" did not cause doctors or hospitals to turn away sicker patients.

23 Apr 2010

Advances in understanding of cardiac-specific genes in heart development

Researchers at the Texas Heart Institute at St. Luke's Episcopal Hospital (THI at St. Luke's) announced today the results of research which they believe marks a significant advance in understanding how cardiac-specific genes are turned on during the development of the heart in mice embryos.

23 Apr 2010

Researchers take major step to predict adverse drug reactions using genetic information

In a new study, researchers at Mount Sinai School of Medicine have taken a major step toward the ability to predict adverse drug reactions, using genetic, cellular, and clinical information to learn why some medicines cause heart arrhythmias in patients. Published in the April 20 issue of the journal Science Signaling, the new framework described in the study could potentially be applied to the study of medications that treat other diseases and disorders such as epilepsy and autism.

23 Apr 2010

Research associates diabetes with atrial fibrillation

As the U.S. population keeps aging and gaining weight, diabetes is becoming increasingly common. Some research has associated diabetes with the most common kind of chronically irregular heartbeat, called atrial fibrillation, which can raise the risk for stroke and death. But results of past studies of diabetes and atrial fibrillation have conflicted.

23 Apr 2010

Geron scientists highlight importance of telomerase inhibitor, GRN163L at AACR 2010

Geron Corporation today announced five presentations by Geron scientists and collaborators on the company's telomerase inhibitor, imetelstat sodium, including the drug's activity against cancer stem cells, at the 101st American Association for Cancer Research annual meeting held in Washington D.C.

23 Apr 2010

Nile Therapeutics prices underwritten public offering of common stock

Nile Therapeutics, Inc., a company focused on the development of novel therapeutics for heart failure patients, announced the pricing of its previously announced underwritten public offering of 6,500,000 units of its securities at a public offering price of $0.70 per unit. Each unit consists of one share of Nile common stock and 0.30 warrants to purchase common stock.

23 Apr 2010

Genentech submits sBLA for Herceptin plus chemotherapy for advanced HER2-positive stomach cancer

Genentech, Inc., a wholly owned member of the Roche Group, announced today that the company submitted a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for Herceptin® (trastuzumab) plus chemotherapy in people with advanced, HER2-positive adenocarcinoma of the stomach, including gastroesophageal junction cancer.

23 Apr 2010

Pfizer announces discontinuation of SUN 1170 Phase 3 study of Sutent in HCC

Pfizer Inc. announced today the discontinuation of the SUN 1170 Phase 3 open-label study of Sutent(r) (sunitinib malate) in advanced hepatocellular carcinoma, or liver cancer. Following a review by the independent Data Monitoring Committee, the study was discontinued based on a higher incidence of serious adverse events in the sunitinib arm compared to the sorafenib arm and the fact that sunitinib did not meet the criteria to demonstrate that it was either superior or non-inferior to sorafenib in the survival of patients with advanced hepatocellular cancer.

23 Apr 2010

Heart Failure News and Research

Further Reading

Thoratec to sell ITC division to Danaher

Covidien introduces PENNSAID to the U.S. market

Beijing Customs seize Biosite's Triage products

Cedars-Sinai Heart Institute presents new findings on heart transplantation rejection factors

Serum cortisol levels linked with increased mortality in patients with ACS: Research

Physician panel to discuss issues related to Qutenza at Investor Day

Novel clinical research approaches for rapidly identifying and preventing congenital cardiovascular defects

HeartWare International presents clinical trial data of Ventricular Assist System at ISHLT annual meeting

Continuous flow mechanical circulatory support devices improve outcomes in patients awaiting heart transplants

SuperSonic Imagine reports results of largest worldwide multicenter clinical breast study in ultrasound imaging

Cardiola's m.pulse MCP based system improves cardiac function in stable CHF patients

Misonix signs exclusive distribution agreement with Suministros Medicos Multimedicas

Study finds no decrease in access to medical care for sicker patients needing CABG surgery

Advances in understanding of cardiac-specific genes in heart development

Researchers take major step to predict adverse drug reactions using genetic information

Research associates diabetes with atrial fibrillation

Geron scientists highlight importance of telomerase inhibitor, GRN163L at AACR 2010

Nile Therapeutics prices underwritten public offering of common stock

Genentech submits sBLA for Herceptin plus chemotherapy for advanced HER2-positive stomach cancer

Pfizer announces discontinuation of SUN 1170 Phase 3 study of Sutent in HCC

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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