Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

Study provides insight into genetic causes of cleft lip and cleft palate

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face.

28 May 2014

Whitehead Institute scientists identify genetic cause of hemifacial microsomia

Whitehead Institute scientists have identified a genetic cause of a facial disorder known as hemifacial microsomia (HFM). The researchers find that duplication of the gene OTX2 induces HFM, the second-most common facial anomaly after cleft lip and palate.

12 May 2014

Scientists find 2 key proteins that regulate growth of mammary stem cells and contribute to breast cancer

By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells-those that can form breast tissue-alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

8 May 2014

UNIGE researchers get closer to unraveling mystery of sexual ambiguity

A team of researchers from the University of Geneva (UNIGE) has been involved in a thorough genetic investigation based on the case of a child suffering from the Nivelon-Nivelon-Mabille Syndrome, a complex condition characterised mainly by a sexual development disorder.

6 May 2014

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

In the 1950s and 1960s, pregnant women with morning sickness were often prescribed the new drug thalidomide. Shortly after the medicine was released on the market, a reported 10,000 infants were born with an extreme form of the rare congenital phocomelia syndrome, which caused death in 50 percent of cases and severe physical and mental disabilities in others.

2 May 2014

Human fat: A Trojan horse to fight brain cancer?

Johns Hopkins researchers say they have successfully used stem cells derived from human body fat to deliver biological treatments directly to the brains of mice with the most common and aggressive form of brain tumor, significantly extending their lives.

1 May 2014

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine.

21 Apr 2014

Researchers discover new marker derived from human umbilical cord blood

The development of stem cell therapies to cure a variety of diseases depends on the ability to characterize stem cell populations based on cell surface markers.

18 Apr 2014

Study proposes new model for understanding how proteins bind together to facilitate cell movement

Cell movement plays an important role in a host of biological functions from embryonic development to repairing wounded tissue. It also enables cancer cells to break free from their sites of origin and migrate throughout the body.

17 Apr 2014

New technique of single-cell genomic analysis to reverse tissue engineering

Consider the marvel of the embryo. It begins as a glob of identical cells that change shape and function as they multiply to become the cells of our lungs, muscles, nerves and all the other specialized tissues of the body.

15 Apr 2014

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

11 Apr 2014

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys. Folliculin's absence or mutated state has a cascading effect that leads to deteriorated lung integrity and an impairment of lung function, as reported in their findings in the current issue of Cell Reports.

11 Apr 2014

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

AVEO Oncology (NASDAQ: AVEO) and Biodesix, Inc. today announced that they have entered into a worldwide agreement to develop and commercialize AVEO's hepatocyte growth factor (HGF) inhibitory antibody ficlatuzumab, with a Biodesix® companion diagnostic test.

10 Apr 2014

Abnormal levels of lipid molecules can trigger autism during prenatal brain development

In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early prenatal brain development, which can trigger autism.

9 Apr 2014

Endurance sport keeps both muscles and nerves fit

Endurance sport does not only change the condition and fitness of muscles but also simultaneously improves the neuronal connections to the muscle fibers based on a muscle-induced feedback.

3 Apr 2014

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles — not their strength or duration. Because such so-called “oscillating signaling cycles” are common in many biological systems, the scientists expect their findings in single-celled organisms to help explain the molecular workings of phenomena such as tissue and organ formation and fundamental forms of learning.

24 Mar 2014

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

Hematopoietic stem cells are now routinely used to treat patients with cancers and other disorders of the blood and immune systems, but researchers knew little about the progenitor cells that give rise to them during embryonic development.

24 Mar 2014

Restless legs syndrome alters expression of critical gene during fetal development of brain

In a study published online in Genome Research, researchers of the Helmholtz Zentrum München und the Technische Universität München have demonstrated that a common genetic variant associated with Restless Legs Syndrome (RLS) alters the expression of a critical gene during fetal development of the brain.

19 Mar 2014

Researchers create new line of human embryonic stem cells

Researchers at the University of Washington have successfully created a line of human embryonic stem cells that have the ability to develop into a far broader range of tissues than most existing cell lines.

18 Mar 2014

3-D imaging of two different mouse models helps understand Apert Syndrome development

Three dimensional imaging of two different mouse models of Apert Syndrome shows that cranial deformation begins before birth and continues, worsening with time, according to a team of researchers who studied mice to better understand and treat the disorder in humans.

4 Mar 2014

Embryonic Development News and Research

Further Reading

Study provides insight into genetic causes of cleft lip and cleft palate

Whitehead Institute scientists identify genetic cause of hemifacial microsomia

Scientists find 2 key proteins that regulate growth of mammary stem cells and contribute to breast cancer

UNIGE researchers get closer to unraveling mystery of sexual ambiguity

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

Human fat: A Trojan horse to fight brain cancer?

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

Researchers discover new marker derived from human umbilical cord blood

Study proposes new model for understanding how proteins bind together to facilitate cell movement

New technique of single-cell genomic analysis to reverse tissue engineering

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Researchers discover mechanism that control normal lung function in patients with BHD syndrome

AVEO joins with Biodesix to develop and commercialize ficlatuzumab for treatment of NSCLC

Abnormal levels of lipid molecules can trigger autism during prenatal brain development

Endurance sport keeps both muscles and nerves fit

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

Restless legs syndrome alters expression of critical gene during fetal development of brain

Researchers create new line of human embryonic stem cells

3-D imaging of two different mouse models helps understand Apert Syndrome development

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