Neurosurgery News and Research

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Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

In cancer, a major obstacle to anti-tumor immunity and immunotherapy treatment is the infiltration of regulatory T cells, or T-reg cells, into a tumor. These immune cells generally turn down the immune response, and they can prevent the immune system from destroying cancer cells.

22 Dec 2021

Researchers evaluate hemodynamic factors related to aneurysm formation

Researchers in Japan have evaluated hemodynamic factors that may help identify sites where aneurysms are likely to form. Detailed findings of this study are described in the article "Computational fluid dynamic analysis of the initiation of cerebral aneurysms" by Soichiro Fujimura et al., published today in the Journal of Neurosurgery.

21 Dec 2021

Study demonstrates decreased lung cancer deaths with early detection

A recent, substantial decline in lung cancer deaths is associated with earlier diagnosis of lung cancer than in the past, supporting the need for increased use of screening to save lives, according to a Mount Sinai study published in JAMA Network Open in December.

18 Dec 2021

A Day in the Life of a Thoracic and Cardiovascular Surgeon

In this interview, we spoke to Dr. Alexander Marmureanu, a thoracic and cardiovascular surgeon, about his day-to-day role and responsibilities as well as his career highlights.

17 Dec 2021

A Day in the Life of a Neurosurgeon

In this interview, we spoke to Jeffrey H. Oppenheimer, a neurosurgeon, about his day-to-day roles and responsibilities as well as his career highlights.

17 Dec 2021

Mount Sinai expands resilience training program to people in its surrounding communities

Mount Sinai's Center for Stress, Resilience and Personal Growth (CSRPG) has expanded its resilience training program to people in its surrounding communities through a partnership with faith-based organizations in Harlem, the Bronx, Brooklyn, and Queens, all disproportionately affected by COVID-19.

16 Dec 2021

Parietooccipital fissure contributes to the invasion pattern of posterior medial temporal gliomas

Researchers from four academic neurosurgical centers in Japan found that the parietooccipital fissure, which divides the temporal, occipital, and parietal lobes of the brain, acts as an obstacle that may result in less invasion of posterior medial temporal gliomas toward the occipital lobe.

14 Dec 2021

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

Researchers discover why people with asthma have lower brain tumor risk

There's not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed.

11 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

New consensus-based recommendations designed to improve quality of life for DMD patients

Many more adults with Duchenne muscular dystrophy (DMD) are living longer thanks to improvements in treatment, however international standards of care have not yet fully addressed the complex needs of these patients.

9 Dec 2021

Study identifies the role of early developmental gene in intracranial aneurysms

Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.

9 Dec 2021

Research provides new insights into debilitating cluster headaches

Debilitating cluster headaches commonly begin in childhood, but patients are not typically diagnosed until they are adults, according to research from The University of Texas Health Science Center at Houston.

8 Dec 2021

Study finds mRNA-based COVID-19 vaccines are effective in cancer patients

The mRNA-based COVID-19 vaccines are effective at preventing infection in most cancer patients, according to a nationwide study of veterans diagnosed with cancer in the past decade.

6 Dec 2021

For older adults, smelling the roses may be more difficult

The reports from covid-19 patients are disconcerting. Only a few hours before, they were enjoying a cup of pungent coffee or the fragrance of flowers in a garden. Then, as if a switch had been flipped, those smells disappeared.

1 Dec 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

UVA researchers develop a noninvasive surgical approach to remove faulty brain circuits

University of Virginia School of Medicine researchers have developed a noninvasive way to remove faulty brain circuits that could allow doctors to treat debilitating neurological diseases without the need for conventional brain surgery.

25 Nov 2021

Finding potential biomarkers to predict response to immunotherapy in nonhypermutated cancers

Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs called immune checkpoint inhibitors, according to findings published in Science Translational Medicine.

24 Nov 2021

Similar brain responses to speech sounds found in humans, macaques and guinea pigs

Speech sounds elicit comparable neural responses and stimulate the same region in the brain of humans, macaques and guinea pigs, a multidisciplinary group of University of Pittsburgh researchers reported in the journal eNeuro today.

21 Nov 2021

New study highlights the important role of rare genomic differences in OCD risk

Both rare and commonly observed differences in the DNA letters strung along a person's chromosomes can explain about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD), according to a new study led by scientists at the Icahn School of Medicine at Mount Sinai.

18 Nov 2021