Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Longer term effects of dementia drugs to be investigated

A £50,000 grant from the Alzheimer's Research Trust will look at whether ACE inhibitors used to treat Alzheimer's could have a longer term effect.

15 Aug 2007

Why is heart disease so prevalent among diabetics?

Heart disease hits people with diabetes twice as often as people without diabetes.

13 Aug 2007

Impaired energy production in heart muscle may underlie heart failure in some hypertensive patients

Many people with long-standing high blood pressure develop heart failure. But some don't. Daniel P. Kelly, M.D., and colleagues at Washington University School of Medicine in St. Louis and other institutions are trying to figure out what could explain that difference.

13 Aug 2007

Diovan (valsartan) granted pediatric exclusivity by FDA

Diovan (valsartan) has been granted pediatric exclusivity by the US Food and Drug Administration (FDA) based on studies conducted in children with high blood pressure.

13 Aug 2007

Improving the quality of primary care could prevent 4 million hospitalizations each year

More than 4 million hospitalizations potentially could be prevented each year by improving the quality of primary care, enhancing patients' access to effective treatments, and getting more Americans to adopt healthy behaviors, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

13 Aug 2007

FDA taking no chances when it comes to drug safety

These days the U.S. Food and Drug Administration (FDA) is taking no chances when it comes to the safety of new drugs.

13 Aug 2007

Antioxidant overload

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key.

12 Aug 2007

Impaired energy production in heart muscle may underlie heart failure in some hypertensive patients

Many people with long-standing high blood pressure develop heart failure.

12 Aug 2007

Connection between reduced glutathione and heart failure

Antioxidants are widely considered an important defense against heart disease, but University of Utah researchers have found excessive levels of one antioxidant - reduced glutathione - actually may contribute to the disease.

12 Aug 2007

Thyroid disease: Understanding hypothyroidism and hyperthyroidism

Doctors often mistake the symptoms of thyroid disease for another disorder such as heart failure, high cholesterol, or even dementia, says a new edition of a report from Harvard Medical School.

11 Aug 2007

Refusal of medical and surgical interventions common among chronically ill elderly

Chronically ill older persons frequently refuse medical and surgical interventions recommended by their physicians, according to a recent study by Yale School of Medicine researchers.

9 Aug 2007

Voluntary exercise induces sex-specific physiological cardiac remodeling

While cardiovascular disease occurs in both men and women, it does not affect them in the same way.

9 Aug 2007

Potential new biomarker for heart failure also strongly predicts risk of death

A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes.

7 Aug 2007

New device to treat chronic congestive heart failure

As part of a 40-site national trial, researchers at UT Southwestern Medical Center are studying a new medical device designed to treat patients with chronic congestive heart failure.

3 Aug 2007

Study compares specialty orthopedic and general hospitals

Specialty orthopedic hospitals serve a healthier population of Medicare patients compared to general hospitals, according to a new study by investigators at the University of Iowa and Department of Veterans Affairs (VA) Iowa City Health Care System.

3 Aug 2007

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Avandia too risky says expert

One of the members of the advisory panel set up to discuss the future of the diabetes pill Avandia says it should be removed from the market because it is too risky and offers no advantage over other alternatives.

30 Jul 2007

Thiazolinediones increase risk of heart failure

A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis by researchers at Wake Forest University School of Medicine and colleagues.

27 Jul 2007

Court rules in favor of Sandoz on Toprol Xl patent

Sandoz was pleased to learn this week that the U.S. Court of Appeals in St. Louis has affirmed a summary judgment by U.S. District Judge Rodney Sippel invalidating patent protection on Toprol XL(R), a beta blocker used to treat angina, heart failure, and high blood pressure.

26 Jul 2007

Metformin gets top grade for diabetes

A type 2 diabetes drug taken orally and in widespread use for more than a decade has been found to have distinct advantages over nine other, mostly newer medications used to control the chronic disease, according to a study by researchers at Johns Hopkins.

26 Jul 2007