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Individualized flu immune responses revealed by high-throughput sequencing

Researchers have shown that it is possible to create personalized, individual-specific measurements of the antibody repertoire in response to influenza vaccination using high-throughput DNA sequencing technology.

11 Feb 2013

Bronchiolitis, air pollution have ‘synergistic effect’ on asthma risk

Results from a Korean study show that a history of bronchiolitis plus exposure to increased levels of air pollution “synergistically” increases a child’s risk for asthma.

11 Feb 2013

Selumetinib shows high response rate for patients with low-grade serous ovarian cancer

Low-grade serous ovarian cancer is less common and aggressive than the high-grade variety, yet exceptionally difficult to treat when frontline therapy fails.

11 Feb 2013

Researchers discover miR-27b that regulates lipid levels in the blood

Researchers have identified a microRNA liver gene, miR-27b, which regulates lipid (cholesterol or fat) levels in the blood. This regulator gene controls multiple genes involved in dyslipidemia-abnormal blood cholesterol levels that can contribute to heart disease.

11 Feb 2013

Combined genomic and proteomic plasma analysis can identify molecular disease mechanisms

For the first time, scientists have combined genomic and proteomic analysis of blood plasma to enhance identification of genetically regulated protein traits. This could be applied to any large association study of civilization diseases where blood plasma has been collected, vastly improving a clinician's ability to identify disease susceptibility in individuals and populations.

11 Feb 2013

Elsevier introduces Journal of Forensic Radiology and Imaging

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announces the launch of Journal of Forensic Radiology and Imaging (JOFRI), the official new journal of the International Society of Forensic Radiology and Imaging (ISFRI).

11 Feb 2013

Case Western Reserve receives $220,000 grant to study gastric cancers

The Case Western Reserve University School of Medicine has received a $220,000 grant from the DeGregorio Family Foundation to study gastric cancers, which remain among the most deadly forms of disease.

11 Feb 2013

MicroRNA can be used to define four subtypes of triple-negative breast cancer

A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.

11 Feb 2013

Nine polio workers killed in northern Nigeria

"Nine female polio vaccinators have been killed in two shootings at health centers in northern Nigeria, police have told the BBC," the news agency reports. "In the first attack in Kano the polio vaccinators were shot dead by gunmen who drove up on a motor tricycle," and "[t]hirty minutes later gunmen targeted a clinic outside Kano city as the vaccinators prepared to start work," BBC News writes.

11 Feb 2013

Nine suggestions to prevent sexual abuse among children

Pediatricians know that when they discuss seat belt, bicycle and water safety during annual wellness visits they are helping to reduce a child's risk of harm. Those same visits should include messages about personal space and privacy, says Dr. Martin A. Finkel, an internationally known expert in the prevention and treatment of child sexual abuse, and he is urging pediatricians to begin a dialogue that will help children avoid the physical and mental health consequences of sexual abuse.

11 Feb 2013

Review describes long-term side-effects of molecularly targeted therapies in children with cancer

A University of Colorado Cancer Center review published this week in the journal Lancet Oncology describes possible long-term side-effects of new, targeted therapies in pediatric cancer patients: what we don't know may hurt us.

11 Feb 2013

Epithelium able to sense bladder fullness through activity of integrins

If you have an overactive bladder or incontinence, help could be on the way. A new research report published online in the FASEB Journal, shows that the epithelium, a thin layer of cells which line the surface of the bladder, is able to sense how full the bladder is through the action of a family of proteins called integrins.

11 Feb 2013

Long-acting reversible contraception with progestin may increase risk of type 2 diabetes in women

A first-of-its-kind study by researchers at the Keck School of Medicine of the University of Southern California (USC) indicates that healthy, obese, reproductive-age women who use long-acting reversible contraception (LARC) containing the hormone progestin have a slightly increased risk for developing type 2 diabetes when compared to those who use non-hormonal contraception.

11 Feb 2013

Researchers utilize molecular genetic engineering to tackle diastolic heart failure

Researchers at the University of Minnesota's Department of Integrative Biology and Physiology and the Lillehei Heart Institute have utilized molecular genetic engineering to optimize heart performance in models of diastolic heart failure by creating an optimized protein that can aid in high-speed relaxation similar to fast twitching muscles.

11 Feb 2013

Study identifies 12 important postoperative complication signs in colorectal surgical patients

Colorectal surgical patients are often discharged from the hospital with vague guidance on how to recognize complications, but researchers at the Michael DeBakey Veterans Administration (VA) Medical Center and Baylor College of Medicine, Houston, aim to change that scenario.

11 Feb 2013

Shanshi, Tensys Medical enter commercial agreement to distribute T-Line technology

Tensys Medical, Inc., a leader in the development and commercialization of continuous, non-invasive hemodynamic patient monitoring systems, has entered into a commercial agreement with Zhejiang Shanshi Medical Device CO., LTD (Shanshi) for distribution of the company's T-Line technology.

11 Feb 2013

Intra-arterial therapy no more effective than IV t-PA in treating acute ischemic stroke

A stroke survivor's chances of living independently after 90 days are not improved by the use of devices inserted into the artery to dissolve or remove a stroke-causing clot shortly after the onset of symptoms, according to a randomized controlled trial involving 656 patients.

11 Feb 2013

Amlexanox also reverses obesity, diabetes and fatty liver in mice

Researchers at the University of Michigan's Life Sciences Institute have found that amlexanox, an off-patent drug currently prescribed for the treatment of asthma and other uses, also reverses obesity, diabetes and fatty liver in mice.

11 Feb 2013

sFRP3 protein appears to be target of both antidepressant drugs and electroconvulsive therapy

Through a series of investigations in mice and humans, Johns Hopkins researchers have identified a protein that appears to be the target of both antidepressant drugs and electroconvulsive therapy.

11 Feb 2013

Diet high in fruits and vegetables may help protect kidneys of patients with CKD

Adding fruits and vegetables to the diet may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build-up, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

10 Feb 2013

Medicine News and Research

Individualized flu immune responses revealed by high-throughput sequencing

Bronchiolitis, air pollution have ‘synergistic effect’ on asthma risk

Selumetinib shows high response rate for patients with low-grade serous ovarian cancer

Researchers discover miR-27b that regulates lipid levels in the blood

Combined genomic and proteomic plasma analysis can identify molecular disease mechanisms

Elsevier introduces Journal of Forensic Radiology and Imaging

Case Western Reserve receives $220,000 grant to study gastric cancers

MicroRNA can be used to define four subtypes of triple-negative breast cancer

Nine polio workers killed in northern Nigeria

Nine suggestions to prevent sexual abuse among children

Review describes long-term side-effects of molecularly targeted therapies in children with cancer

Epithelium able to sense bladder fullness through activity of integrins

Long-acting reversible contraception with progestin may increase risk of type 2 diabetes in women

Researchers utilize molecular genetic engineering to tackle diastolic heart failure

Study identifies 12 important postoperative complication signs in colorectal surgical patients

Shanshi, Tensys Medical enter commercial agreement to distribute T-Line technology

Intra-arterial therapy no more effective than IV t-PA in treating acute ischemic stroke

Amlexanox also reverses obesity, diabetes and fatty liver in mice

sFRP3 protein appears to be target of both antidepressant drugs and electroconvulsive therapy

Diet high in fruits and vegetables may help protect kidneys of patients with CKD

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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