Neurosurgery News and Research

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Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical therapies for movement disorders, leads a team that has been awarded a three-year, $8.9 million grant from the Aligning Science Across Parkinson's (ASAP) initiative.

26 Oct 2021

DOD funds first human trial of a device to enhance the natural brain cleansing system

The U.S. Department of Defense is funding the first human trial of a device to speed up and enhance the natural system of brain cleansing that occurs when we sleep.

26 Oct 2021

U of M Udall Center receives $11.3 million grant to continue research on deep brain stimulation for Parkinson’s disease

The Udall Center at the University of Minnesota Medical School was awarded a new $11.3 million grant from the National Institute for Neurological Disorders and Stroke to continue its work in deep brain stimulation (DBS) for Parkinson's disease.

25 Oct 2021

Study maps neurons essential for social behavior and healthy relationships within groups

Meaningful social interactions are critical to an individual's well-being, and such interactions rely on people's behaviors towards one another.

22 Oct 2021

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Targeting the dentate nucleus with deep brain stimulation (DBS) was safe and feasible for promoting post-stroke rehabilitation in a first-in-human study at Cleveland Clinic.

21 Oct 2021

New AI-based computer algorithm may enable quicker diagnosis of heart failure

A special artificial intelligence (AI)-based computer algorithm created by Mount Sinai researchers was able to learn how to identify subtle changes in electrocardiograms (also known as ECGs or EKGs) to predict whether a patient was experiencing heart failure.

19 Oct 2021

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

13 Oct 2021

Study uncovers toxic air pollutant mixtures linked to poor childhood asthma outcomes

Researchers at the Icahn School of Medicine at Mount Sinai have developed a novel machine learning algorithm and used it to identify previously unknown mixtures of toxic air pollutants that appear to be linked to poor asthma outcomes later in a child's life.

8 Oct 2021

New approach to guided nerve repair by using gingiva-derived mesenchymal stem cells

A new approach to repairing peripheral nerves marries the regenerating power of gingiva-derived mesenchymal stem cells with a biological scaffold to enable the functional recovery of nerves following a facial injury, according to a study by a cross-disciplinary team from the University of Pennsylvania School of Dental Medicine and Perelman School of Medicine.

8 Oct 2021

Study uncovers new drug target for myelodysplastic syndrome

Mount Sinai and UC San Diego researchers have shown for the first time how mutations affecting a cellular process called RNA splicing alter cells to develop myelodysplastic syndrome (MDS) and other hematologic malignancies and solid tumors, according to a study published in Cancer Discovery in October.

7 Oct 2021

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

NYU Langone Health broadens access to high-quality primary and specialty care

NYU Langone Health continues to broaden access to high-quality primary and specialty care with recent expansions in Long Island, Queens, Manhattan, and Brooklyn.

5 Oct 2021

Blacks, Latinos with autoimmune diseases experience poorer outcomes due to modifiable social conditions

Minority populations in the US with multiple sclerosis and other autoimmune diseases experience poorer outcomes due to modifiable social conditions, according to a new USC study.

5 Oct 2021

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Glioblastoma is one of the deadliest cancers known to man. While the advent of immunotherapy and other cutting-edge treatments have prolonged life for people afflicted with other types of cancer, the prognosis for glioblastoma has remained relatively constant: just 18 months.

3 Oct 2021

Novel small-molecule therapy shows promise against deadly pediatric leukemia

Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.

29 Sep 2021

Long-held theory of cancer-induced immune suppression requires revision, study says

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

29 Sep 2021

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Kristina Simonyan, MD, PhD, Dr med, director of laryngology research at Mass Eye and Ear, has been awarded an $11.9 million P50 Clinical Research Center Grant from the National Institute on Deafness and Other Communicable Disorders of the National Institute of Health to form a new multidisciplinary center across four academic medical institutions that will be committed to conducting research on laryngeal dystonia and voice tremor, two debilitating neurological voice disorders.

28 Sep 2021

Diminished waveforms on EKGs of hospitalized patients can help predict worsening health, death

Specific and dynamic changes on electrocardiograms (EKGs) of hospitalized patients with COVID-19 or influenza can help predict a timeframe for worsening health and death, according to a new Mount Sinai study.

25 Sep 2021

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

As mRNA-based SARS-CoV-2 vaccines are deployed to protect hundreds of millions of people across the world and point the way to end the deadly global COVID-19 pandemic, the University of Pennsylvania scientists whose prescient discovery science effort laid the foundation for swift vaccine development have been awarded the 2021 Lasker~DeBakey Clinical Medical Research Award.

24 Sep 2021

New mutations enable gliomas to resist proven treatment, study shows

About one-third of all brain tumors are gliomas, cancerous growths that originate in the glial cells that surround and support neurons in the brain. The prognosis for patients with gliomas is not good, with the average survival time being 12-18 months.

24 Sep 2021

Neurosurgery News and Research

Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

DOD funds first human trial of a device to enhance the natural brain cleansing system

U of M Udall Center receives $11.3 million grant to continue research on deep brain stimulation for Parkinson’s disease

Study maps neurons essential for social behavior and healthy relationships within groups

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

New AI-based computer algorithm may enable quicker diagnosis of heart failure

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

Study uncovers toxic air pollutant mixtures linked to poor childhood asthma outcomes

New approach to guided nerve repair by using gingiva-derived mesenchymal stem cells

Study uncovers new drug target for myelodysplastic syndrome

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

NYU Langone Health broadens access to high-quality primary and specialty care

Blacks, Latinos with autoimmune diseases experience poorer outcomes due to modifiable social conditions

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Novel small-molecule therapy shows promise against deadly pediatric leukemia

Long-held theory of cancer-induced immune suppression requires revision, study says

Mass Eye and Ear researcher receives P50 NIH grant to establish new center for neurological voice disorders

Diminished waveforms on EKGs of hospitalized patients can help predict worsening health, death

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

New mutations enable gliomas to resist proven treatment, study shows

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