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Researchers identify never-before-defined subtypes of a blood cancer

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

17 Nov 2021

Young adults with cancer may require different treatments than older patients

Not all tumors are alike. Young adults who are diagnosed with skin, colon, and other cancer types may require different treatments than older patients receive.

16 Nov 2021

Tighter blood pressure management may lead to better spinal cord injury recovery

Patients with new spinal cord injuries whose blood pressure is maintained within a newly defined range during surgery may stand a better chance of regaining some mobility and functionality – even in patients with the most devastating injuries – according to a new study by researchers at UC San Francisco.

16 Nov 2021

Simple risk score can help predict contrast-associated kidney injury after PCI

A new, updated risk score can help predict possible contrast-associated acute kidney injury (CA-AKI) among patients undergoing percutaneous coronary intervention (PCI), Mount Sinai researchers report.

15 Nov 2021

Combination treatment improves overall survival for melanoma patients with brain metastases

Combination treatment with immune checkpoint inhibitors nivolumab and ipilimumab demonstrates overall survival for patients with melanoma that has spread to the brain, according to Phase II study results published today in The Lancet Oncology by researchers from The University of Texas MD Anderson Cancer Center.

11 Nov 2021

Study investigates whether obesity protects against subarachnoid hemorrhage

According to a major Finnish-Norwegian study, the previously reported association of obesity with a lower risk of subarachnoid hemorrhage appears to be primarily explained by people's smoking habits.

11 Nov 2021

Study explores the impact of ethnicity on brain tumor survival

White British people who have been diagnosed with a malignant primary brain tumor appear to be more likely to die within one year than patients from at least four other ethnic groups according to a study presented at the NCRI Festival.

9 Nov 2021

Repeated listening to favorite music induces beneficial brain plasticity in Alzheimer’s patients

Researchers at the University of Toronto and Unity Health Toronto have demonstrated that repeated listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer's disease.

9 Nov 2021

CHOP-led network receives NIH-supported resources to unlock mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia (CHOP). The Children's Brain Tumor Network (CBTN), a multi-institutional brain tumor research program with its operations center housed at D3b, has collected tumor samples from patients all over the world.

3 Nov 2021

Northwestern scientists receive awards totaling nearly $18 million for Parkinson's disease research

Northwestern University scientists have received two awards totaling nearly $18 million for Parkinson's disease research from The ASAP Collaborative Research Network, a program of the Aligning Science Across Parkinson's (ASAP) initiative being implemented through The Michael J. Fox Foundation.

27 Oct 2021

Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical therapies for movement disorders, leads a team that has been awarded a three-year, $8.9 million grant from the Aligning Science Across Parkinson's (ASAP) initiative.

26 Oct 2021

DOD funds first human trial of a device to enhance the natural brain cleansing system

The U.S. Department of Defense is funding the first human trial of a device to speed up and enhance the natural system of brain cleansing that occurs when we sleep.

26 Oct 2021

U of M Udall Center receives $11.3 million grant to continue research on deep brain stimulation for Parkinson’s disease

The Udall Center at the University of Minnesota Medical School was awarded a new $11.3 million grant from the National Institute for Neurological Disorders and Stroke to continue its work in deep brain stimulation (DBS) for Parkinson's disease.

25 Oct 2021

Study maps neurons essential for social behavior and healthy relationships within groups

Meaningful social interactions are critical to an individual's well-being, and such interactions rely on people's behaviors towards one another.

22 Oct 2021

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Targeting the dentate nucleus with deep brain stimulation (DBS) was safe and feasible for promoting post-stroke rehabilitation in a first-in-human study at Cleveland Clinic.

21 Oct 2021

New AI-based computer algorithm may enable quicker diagnosis of heart failure

A special artificial intelligence (AI)-based computer algorithm created by Mount Sinai researchers was able to learn how to identify subtle changes in electrocardiograms (also known as ECGs or EKGs) to predict whether a patient was experiencing heart failure.

19 Oct 2021

MR-guided focused ultrasound can safely deliver antibody therapy to Her2-positive brain metastases

In a first-in-world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain.

13 Oct 2021

Study uncovers toxic air pollutant mixtures linked to poor childhood asthma outcomes

Researchers at the Icahn School of Medicine at Mount Sinai have developed a novel machine learning algorithm and used it to identify previously unknown mixtures of toxic air pollutants that appear to be linked to poor asthma outcomes later in a child's life.

8 Oct 2021

New approach to guided nerve repair by using gingiva-derived mesenchymal stem cells

A new approach to repairing peripheral nerves marries the regenerating power of gingiva-derived mesenchymal stem cells with a biological scaffold to enable the functional recovery of nerves following a facial injury, according to a study by a cross-disciplinary team from the University of Pennsylvania School of Dental Medicine and Perelman School of Medicine.