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Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

Discovery provides new hope for anti-HIV vaccine

Researchers have discovered that the RNA genome of the HIV virus can influence the immune response generated, and thus influence human survival.

10 Sep 2018

BeiGene collaborates with SpringWorks to evaluate new combinational therapy for solid tumors

BeiGene, Ltd., a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly-targeted and immuno-oncology drugs for the treatment of cancer, and SpringWorks Therapeutics, a clinical-stage rare disease and oncology company focused on sourcing and developing innovative treatments for underserved patient populations, announced today that the companies have entered into a global clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of combining BeiGene's investigational RAF dimer inhibitor, lifirafenib and SpringWorks Therapeutics' investigational MEK inhibitor, PD-0325901, in patients with advanced solid tumors.

6 Sep 2018

Doctor with Guillain Barré syndrome recovers back to normal life

Doctors do the darndest things. Take the one who walked right up to Dan Thomas, MD, at a lecture, got into the ready position, and proceeded to perform several squats as Thomas watched, puzzled.

6 Sep 2018

Researchers find bacterial DNA in intestine of newborn calves

Researchers at the University of Helsinki, Finland have found bacterial DNA in the intestine of newborn calves, representing quite a diverse variety of bacterial species.

6 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Researchers discover key aspect in pathogenesis of multiple sclerosis

A team of researchers the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain.

4 Sep 2018

Neutrophil nanosponges provide hope for rheumatoid arthritis

Scientists in San Diego have developed nanosponges coated in neutrophil membranes that can prevent rheumatoid arthritis.

3 Sep 2018

Subcutaneous injection of new protein helps treat hemophilia more effectively

Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also happen into any tissue in the body including the muscles, brain, or eyes.

31 Aug 2018

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

A $2 million phase 2 Small Business Technology Transfer grant to optimize a promising new compound that has shown efficacy in preclinical studies against treatment-resistant multiple myeloma has been awarded to a Medical University of South Carolina startup company, Leukogene Therapeutics, Inc., in collaboration with MUSC researcher and company founder, Nathan G. Dolloff, Ph.D. Dolloff is an assistant professor in the Department of Cell and Molecular Pharmacology & Experimental Therapeutics at MUSC and a member of MUSC Hollings Cancer Center.

31 Aug 2018

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs.

30 Aug 2018

New study reports key steps towards development of acne vaccine

A new study published in the Journal of Investigative Dermatology reports important steps that have been taken towards the development of an acne vaccine.

29 Aug 2018

Protein modifications that indicate disease

Researchers from the University of Zurich can, for the first time, precisely characterize the protein modification ADP-ribosylation for all proteins in a tissue sample.

28 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018

Immune-related enzymes cause aggressive skin cancer in patients with Butterfly Syndrome

Patients with a rare skin disease, commonly called Butterfly Syndrome, that causes chronic blistering and extensive scarring also develop an aggressive and fatal form of cancer early in life.

28 Aug 2018

Scientists develop urine diagnostic to detect parasitic worms that cause river blindness

Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide.

28 Aug 2018

Pancreas' network of enzyme ducts resembles formation of rivers

With methods used to analyze road systems and rivers researchers from the University of Copenhagen have studied the formation of the pancreas' network of ducts transporting digestive enzymes in mice.

27 Aug 2018

Study provides new insights into how the human immune system protects against Ebola infections

Two types of human antibodies that target different parts of the Ebola virus synergize their antiviral effects by inhibiting different steps of infection, according to a study published August 23 in the open-access journal PLOS Pathogens by Philipp Ilinykh and colleagues from the University of Texas Medical Branch, Vanderbilt University, and Ragon Institute.

24 Aug 2018

Scientists create new method of particle tracking based on machine learning

Scientists at the University of North Carolina at Chapel Hill have created a new method of particle tracking based on machine learning that is far more accurate and provides better automation than techniques currently in use.

24 Aug 2018

'Plastic antibodies' effectively target and eliminate tumor cells

A joint research team from Russia and the U.K. has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or "plastic antibodies." NanoMIPs are synthetic polymers that can function as antibodies, selectively binding to target proteins on the surface of cancer cells.

23 Aug 2018