Antibodies News and Research

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Novavax SARS-CoV-2 vaccine candidate shows promise in animal models

A new study published on the preprint server bioRxiv in June 2020 shows that a candidate spike protein vaccine can induce neutralizing antibodies, antiviral T cell responses, and protection against infection.

2 Jul 2020

Coronavirus immunity is higher than previously thought, study finds

Now, a team of researchers at the Karolinska Institutet and Karolinska University Hospital in Sweden has found that the number of people immune to COVID-10 may be higher than previously thought, and that antibody testing may no longer be the appropriate tool to trace it.

1 Jul 2020

Important new findings on T cell immunity in COVID-19

Researchers at the Karolinska University Hospital and University Hospital of Wales report that people who have recovered from asymptomatic or mild cases of coronavirus disease 2019 (COVID-19) may have long-term T-cell immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

Striking CryoEM image of SARS-CoV-2

A new study by researchers from the UK and Germany and published on the preprint server bioRxiv in June 2020 reports the results of a detailed study of the S protein on the intact virus, using cryoelectron microscopy (cryoEM) and tomography. This could help understand the conformation of the S protein on the virion and how it interacts with neutralizing antibodies.

30 Jun 2020

New approach holds incredible potential for developing new therapeutics

Nearly every drug that is, or has ever been, used was derived from nature -- harnessing compounds created by organisms over eons to fight diseases. But decades ago, biochemists postulated that it might be possible to design a new drug from scratch by linking up amino acids in precise ways.

30 Jun 2020

Large-scale analysis of COVID-19 risk among different groups of UK hospital staff

Staff who shared a household with an infected person were at the greatest risk of infection, and those working in COVID-19-facing areas were also at an increased risk. Other groups that were identified as a high risk included Black and Asian individuals, porters, and cleaners.

30 Jun 2020

Researchers develop technique for personalizing stomach cancer therapy

Researchers from the Moscow Institute of Physics and Technology and their colleagues have developed the first technique for personalizing stomach cancer therapy based on RNA sequencing of tumor cells. The study, supported by the Russian Science Foundation, was published in Cold Spring Harbor Molecular Case Studies.

30 Jun 2020

Potential new biomarker could improve COVID-19 diagnosis

Researchers at Montpellier University Hospital have discovered that an interferon-inducible receptor expressed on monocytes could be a useful biomarker for the rapid triaging of patients suspected to have severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Jun 2020

New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

30 Jun 2020

Engineered immune cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

30 Jun 2020

Study: Even the sickest COVID-19 patients produce T cells that help fight the virus

A new study from researchers at La Jolla Institute for Immunology (LJI) and Erasmus University Medical Center (Erasmus MC) shows that even the sickest COVID-19 patients produce T cells that help fight the virus.

30 Jun 2020

Modified Vaccinia Ankara-based vaccine candidate for SARS-CoV-2

Now, a new study by researchers at Emory University, the University of Texas Medical Branch and the Ragon Institute and published on the preprint server bioRxiv in June 2020 reports the development of a promising new vaccine candidate that may rapidly and effectively induce the production of neutralizing antibodies against the spike protein of the virus.

30 Jun 2020

WHO says worst is yet to come as COVID-19 pandemic speeds up

The true number of global infections and deaths, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is likely to be significantly higher due to lack of testing. Some people are also asymptomatic, which means they had no symptoms of the illness.

29 Jun 2020

A glycan analysis of SARS-CoV-2 ACE2 complex

Researchers in the U.S. have produced molecular dynamic simulations of the Spike protein found on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its interaction with the host cell receptor angiotensin-converting enzyme 2 (ACE2).

29 Jun 2020

Sanford Burnham Prebys announces research agreement with Lilly to identify COVID-19 antibodies

Sanford Burnham Prebys Medical Discovery Institute today announced a research agreement with Eli Lilly and Company (Lilly) to characterize Lilly's next-generation anti-SARS-CoV-2 antibodies.

29 Jun 2020

Live attenuated vaccines may prevent lung inflammation and sepsis associated with COVID-19

A paper published by Paul Fidel, Jr., PhD, Professor and Director of the Center of Excellence in Oral and Craniofacial Biology and Associate Dean for Research at LSU Health New Orleans School of Dentistry, and Mairi Noverr, PhD, Professor of Microbiology & Immunology at Tulane University School of Medicine in New Orleans, suggests that live attenuated vaccines such as MMR (measles, mumps and rubella) may prevent the severe lung inflammation and sepsis associated with COVID-19 infection.

26 Jun 2020