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New strategy may prevent spread of drug resistance

Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems.

10 Jan 2019

Bacteria on the International Space Station are adapting to survive, not to harm

Mutant bacteria stranded in space by visiting astronauts have been adapting to survive in their new environment, according to a new study.

10 Jan 2019

Viral replication not necessary to cause lethal disease by food-borne pathogen

The replication of a bacterial virus is not necessary to cause lethal disease in a mouse model of a food-borne pathogen called Enterohemorrhagic Escherichia coli, according to a study published January 10 in the open-access journal PLOS Pathogens by Sowmya Balasubramanian, John Leong and Marcia Osburne of Tufts University School of Medicine, and colleagues.

10 Jan 2019

New bacteria discovered in the blood of human patients

Two new species of bacteria have been found in the blood of patients in China.

10 Jan 2019

Microbial metabolite from pomegranates can reduce and protect against IBD

Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease.

10 Jan 2019

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Alison Weiss, PhD, professor in the Department of Molecular Genetics, Biochemistry and Microbiology in UC College of Medicine, has been awarded a four-year grant of $1.6 million from the National Institute of Allergy and Infectious Diseases to study Shiga toxin producing Escherichia coli 0157:H7, also sometimes referred to as Hamburger E. coli.

9 Jan 2019

UC San Diego to conduct first U.S. clinical trial of intravenously administered bacteriophage therapy

The U.S. Food and Drug Administration has accepted an Investigational New Drug application by physician-scientists at University of California San Diego School of Medicine to conduct the first U.S. clinical trial of an intravenously administered bacteriophage-based therapy.

9 Jan 2019

FDA approves initiation of first-in-human trial of DNA-encoded monoclonal antibody

The Wistar Institute, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc., announce that the FDA has approved the initiation of a first-in-human clinical trial investigating the safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody therapeutic technology for the prevention of Zika virus infection.

9 Jan 2019

Study offers new insight on mechanism underlying control of gene expression

Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.

8 Jan 2019

Scientists explore bacterial immunity to better understand infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death.

8 Jan 2019

Study shows link between antibiotic resistance in the environment and fecal pollution

Increased levels of antibiotic-resistant bacteria in the environment may have different causes. It could be a consequence of on-site selection from antibiotic residues in the environment, hence promoting the evolution of new forms of resistance.

8 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

MD Anderson Cancer Center and 4D pharma team up to evaluate live biotherapeutic oncology pipeline

The University of Texas MD Anderson Cancer Center and 4D pharma today announced a strategic collaboration to evaluate 4D's live biotherapeutic oncology pipeline across a range of cancer settings.

7 Jan 2019

New, potential therapy can disrupt myeloid cells that promote tumor growth

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread).

7 Jan 2019

One reason behind frequent miscarriages could be faulty sperms

Scientists at the Imperial College in London have found that one of the reasons behind frequent miscarriages in a woman could be the fault of the sperms of their partners. Recurrent miscarriages are defined as three or more miscarriages that occur before 20 weeks of pregnancy are completed. One in 50 couples in the UK are affected by recurrent miscarriages.

6 Jan 2019