Vascular News and Research

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Cholesterol-lowering statins reduce rate of mortality and cardiovascular events

Over the long term, treatment with cholesterol-lowering statins reduces the rate of mortality and cardiovascular events such as heart attack, for people with and without heart disease. Still, it is unclear whether these drugs take effect rapidly when the risk of these dire events is highest.

15 Jun 2011

ESC publishes position paper to raise the profile of vulnerable plaques

The European Society of Cardiology (ESC) Working Group of Atherosclerosis and Vascular Biology has published a position paper to raise the profile of vulnerable plaques and the need for greater use of therapies to promote plaque stabilisation.

15 Jun 2011

BDC releases new technology to aid medical device industry with product design testing

Endovascular stents, stent grafts, and transcatheter heart valve (TAVI) devices provide enhanced methods for clinical treatment of cardiac and vascular disease. Further research and product development is currently ongoing worldwide to address complications associated with these devices.

15 Jun 2011

New ultrasound technique can measure blood pressure at many points in the body

Researchers at Eindhoven University of Technology, together with the Italian company Esaote, have developed a new technique to measure the blood pressure.

15 Jun 2011

Actelion awards grants to 2011 ENTELLIGENCE young investigators for research in pulmonary arterial hypertension

Actelion Pharmaceuticals US, Inc. and the ENTELLIGENCE Steering Committee recognized four young researchers and their mentors for their efforts in advancing research in PAH. Each researcher will receive a 12-month mentored grant of up to $100,000 in support, funded through the ENTELLIGENCE program supported by Actelion. The announcement was made at an awards luncheon, during which the recipients of the 2011 awards gave an overview of their proposed work.

14 Jun 2011

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiorenal disease, announced it successfully completed patient enrollment in its phase II Contrast-Induced Acute Kidney Injury study with its oral drug candidate CRMD001.

14 Jun 2011

The Lancet publishes final 3-year data from landmark HORIZONS-AMI clinical trial

Data from the landmark HORIZONS-AMI clinical trial demonstrated that the administration of the anticoagulant medication bivalirudin enhanced survival compared to the use of heparin plus a glycoprotein (GP) IIb/IIIa inhibitor in heart attack patients undergoing angioplasty after 3 years. Use of a drug-eluting stent was also shown to be more effective than a bare-metal stent, with equivalent safety.

14 Jun 2011

Individuals with chronic vascular disease can benefit from echo-mediated gene therapy

Researchers today announced the results of a study that show echocardiography can improve the success rate of gene therapy and increase growth, function and sustainability of regenerated vessels.

14 Jun 2011

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Critical Path Institute (C-Path) and the Innovative Medicines Initiative (IMI) announced today that they have signed a Memorandum of Understanding (MoU) to further the missions of both organizations.

14 Jun 2011

Poor maternal nutrition predisposes offspring to type 2 diabetes

A new study published by the American Physiological Society offers the strongest evidence yet that vulnerability to type 2 diabetes can begin in the womb, giving new insight into the mechanisms that underlie a potentially devastating disease at the center of a worldwide epidemic.

14 Jun 2011

Researchers discover genetic factor that can regulate obesity-induced inflammation

Researchers at Case Western Reserve University School of Medicine have discovered a genetic factor that can regulate obesity-induced inflammation that contributes to chronic health problems.

14 Jun 2011

GE Healthcare announces results of Optison heart ultrasound contrast agent presented at ASE

Today, GE Healthcare Medical Diagnostics announced results of a study that evaluated the cardiopulmonary safety of Optison- (Perflutren Protein-Type A Microspheres Injectable Suspension, USP), a diagnostic ultrasound contrast agent for use in improving suboptimal echocardiograms.

14 Jun 2011

Left ventricular assist device increases incidence of internal bleeding in heart failure patients

The incidence of internal bleeding was higher in the most commonly implanted heart device than in an earlier model, according to two studies at Henry Ford Hospital in Detroit.

13 Jun 2011

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

13 Jun 2011

ACS honors Los Angeles general surgeon with 2011 Jacobson Innovation Award

George Berci, MD, FACS, FRCS, Ed. (Hon), a general surgeon from Los Angeles, CA, is the recipient of the 2011 Jacobson Innovation Award of the American College of Surgeons.

13 Jun 2011

Cell division linked to oxygen levels: Johns Hopkins research

Cells grow abundant when oxygen is available, and generally stop when it is scarce. Although this seems straightforward, no direct link ever has been established between the cellular machinery that senses oxygen and that which controls cell division. Now, in the June 10 issue of Molecular Cell, researchers at Johns Hopkins report that the MCM proteins, which promote cell division, also directly control the oxygen-sensing HIF-1 protein.

12 Jun 2011

Exercise protects against silent stroke: Study

Strokes can cause brain damage by cutting off blood flow to the brain. But unlike major strokes, recognizable by symptoms such as weakness on one side of the body and trouble speaking, so-called silent strokes by definition go unnoticed. Symptoms can include subtle memory and mobility problems, as well as an increased risk for future strokes, according to the American Academy of Neurology. Silent strokes are also different from mini-strokes, which are noticeable but last only for minutes or hours.

9 Jun 2011

ASI announces successful completion of $10 million round of financing

Access Scientific, Inc. (ASI) today announced the successful completion of a $10 million round of financing. The round was led by CAC and further supported by the company's previous institutional investors.

9 Jun 2011

Older people who engage in moderate to intense exercise less likely to have silent strokes

Older people who regularly exercise at a moderate to intense level may be less likely to develop the small brain lesions, sometimes referred to as "silent strokes," that are the first sign of cerebrovascular disease, according to a new study published in the June 8, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jun 2011

Key molecule of vascular system directs axons during neural circuit formation

Dr. Fr-d-ric Charron, researcher at the Institut de recherches cliniques de Montr-al (IRCM), and his team have shown for the first time that a key molecule of the vascular system directs axons during the formation of neural circuits.

9 Jun 2011

Vascular News and Research

Cholesterol-lowering statins reduce rate of mortality and cardiovascular events

ESC publishes position paper to raise the profile of vulnerable plaques

BDC releases new technology to aid medical device industry with product design testing

New ultrasound technique can measure blood pressure at many points in the body

Actelion awards grants to 2011 ENTELLIGENCE young investigators for research in pulmonary arterial hypertension

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

The Lancet publishes final 3-year data from landmark HORIZONS-AMI clinical trial

Individuals with chronic vascular disease can benefit from echo-mediated gene therapy

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Poor maternal nutrition predisposes offspring to type 2 diabetes

Researchers discover genetic factor that can regulate obesity-induced inflammation

GE Healthcare announces results of Optison heart ultrasound contrast agent presented at ASE

Left ventricular assist device increases incidence of internal bleeding in heart failure patients

MCMs mediate crosstalk between cell division machinery and oxygen-sensing protein

ACS honors Los Angeles general surgeon with 2011 Jacobson Innovation Award

Cell division linked to oxygen levels: Johns Hopkins research

Exercise protects against silent stroke: Study

ASI announces successful completion of $10 million round of financing

Older people who engage in moderate to intense exercise less likely to have silent strokes

Key molecule of vascular system directs axons during neural circuit formation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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