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Researchers identify key molecule responsible for breast tumor metastasis

Researchers at Albert Einstein College of Medicine of Yeshiva University have identified a key player in the spread of breast cancer. The findings, published today in the online edition of Nature, identify a critical molecule that helps cancer spread beyond the primary tumor.

9 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

Adoption of premium-priced sclerotherapy agents will contribute to growth of US sclerotherapy market

According to Millennium Research Group (MRG), the global authority on medical technology market intelligence, the United States sclerotherapy market will experience rapid procedural growth stemming from favorable patient demographics and increased patient demand. Polidocanol, a sclerosing agent used to chemically treat varicose and spider veins, received FDA approval in 2010 and is expected to show significant growth in the US.

8 Jun 2011

U.S. District Court rules in favor of Boston Scientific in PROMUS patent lawsuit

Boston Scientific Corporation today announced that the U.S. Court of Appeals for the Federal Circuit affirmed the decision of the U.S. District Court for the District of Delaware, finding all four patents in a suit involving Johnson & Johnson to be invalid.

8 Jun 2011

Top-line results from Cipher's CIP-ISOTRETINOIN Phase III study against severe nodular acne

Cipher Pharmaceuticals Inc. today provided top-line safety and efficacy results from the Phase III safety study of CIP-ISOTRETINOIN, the Company's novel, patented formulation of isotretinoin for the treatment of severe, nodular acne.

8 Jun 2011

Stent graft can repair abdominal aortic aneurysm

When Dr. Ross Milner repaired Lydia Strebing's life-threatening abdominal aortic aneurysm, she was astonished at how easy it was. "I've had more pain from dental procedures," she said. "This was nothing." Milner, chief of vascular surgery at Loyola University Hospital, repaired the bulging aneurysm by using a catheter to deploy a device called a stent graft.

8 Jun 2011

Low phosphate intake can reduce heart disease

Lowering phosphate intake in humans can reduce heart disease, according to research by experts at the University of Sheffield.

8 Jun 2011

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced clinical and preclinical data from its lead program, KAI-4169, at the Endocrine Society's 93rd Annual Meeting (ENDO 2011) taking place in Boston, June 4-7, 2011. KAI-4169 is a novel pharmaceutical agent being developed for the treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD).

7 Jun 2011

LUMEDX releases new Webinar, The Power of Analytics: Managing Cath Lab Growth in Real Time

LUMEDX Corporation, a leading provider of integrated cardiovascular information systems (CVIS), today announced the release of a new and complimentary educational Webinar on CD, The Power of Analytics: Managing Cath Lab Growth in Real Time.

7 Jun 2011

Scientists discover key molecule that targets tumour blood vessels

Scientists at the Walter and Eliza Hall Institute have discovered a key molecule needed to kill the blood vessels that supply tumours.

7 Jun 2011

Silencing two microRNAs may help treat age-related macular degeneration

Blocking two tiny molecules of RNA - a chemical cousin of DNA - appears to suppress the abnormal growth of blood vessels that occurs in degenerative eye disorders, UT Southwestern Medical Center researchers have found.

7 Jun 2011

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Pathway Medical Technologies, Inc, an innovator of endovascular treatments for peripheral vascular disease (PVD), announced today that the U.S. Food and Drug Administration (FDA) has granted the company 510(k) clearance to market JETSTREAM Navitus, an enhanced revascularization catheter for the treatment of PVD.

6 Jun 2011

Global gene therapy market to reach $300 million by 2015

The global gene therapy market is expected to grow to over $300 million by 2015, according to a new report available on companiesandmarkets.com. The gene therapy market will grow further driven by the human genome project, the increasing incidence of cancer and other critical diseases.

6 Jun 2011

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

United Therapeutics Corporation announced today the completion of its FREEDOM-M Phase 3 trial of treprostinil diethanolamine, an investigational sustained release oral formulation of treprostinil, a stable synthetic form of prostacyclin, in patients with pulmonary arterial hypertension (PAH).

6 Jun 2011

Super microscopes help scientists identify exact molecular 'switch' that spurs T-cells into action

Using the only microscope of its kind in Australia, medical scientists have been able for the first time to see the inner workings of T-cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream.

6 Jun 2011

Scientists use super microscope to pinpoint body’s immunity ‘switch’

5 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

Combinations of mother's body size, placental size can predict heart disease in men in later life: Study

Researchers investigating the foetal origins of chronic disease have discovered that combinations of a mother's body size and the shape and size of her baby's placenta can predict heart disease in men in later life.

4 Jun 2011

Johns Hopkins researchers solve long-standing mystery of Warburg effect

It's long been known that cancer cells eat a lot of sugar to stay alive. In fact, where normal, noncancerous cells generate energy from using some sugar and a lot of oxygen, cancerous cells use virtually no oxygen and a lot of sugar.

4 Jun 2011

Study to determine how vitamin D affects cardiac structure, functions in blacks with hypertension

A Wayne State University School of Medicine physician researcher has received a $1.9 million National Institutes of Health grant to study the role of vitamin D in halting and reducing subclinical cardiac damage in African-Americans suffering from high blood pressure.

3 Jun 2011

Vascular News and Research

Researchers identify key molecule responsible for breast tumor metastasis

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Adoption of premium-priced sclerotherapy agents will contribute to growth of US sclerotherapy market

U.S. District Court rules in favor of Boston Scientific in PROMUS patent lawsuit

Top-line results from Cipher's CIP-ISOTRETINOIN Phase III study against severe nodular acne

Stent graft can repair abdominal aortic aneurysm

Low phosphate intake can reduce heart disease

Promising results from KAI-4169 program for CKD-MBD presented at ENDO 2011

LUMEDX releases new Webinar, The Power of Analytics: Managing Cath Lab Growth in Real Time

Scientists discover key molecule that targets tumour blood vessels

Silencing two microRNAs may help treat age-related macular degeneration

FDA grants Pathway marketing clearance for JETSTREAM Navitus revascularization catheter for PVD

Global gene therapy market to reach $300 million by 2015

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

Super microscopes help scientists identify exact molecular 'switch' that spurs T-cells into action

Scientists use super microscope to pinpoint body’s immunity ‘switch’

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Combinations of mother's body size, placental size can predict heart disease in men in later life: Study

Johns Hopkins researchers solve long-standing mystery of Warburg effect

Study to determine how vitamin D affects cardiac structure, functions in blacks with hypertension

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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