Genetic Engineering News and Research

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Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease. In order for this tau pathology to spread, the protein must interact with heparan sulfate, a sugar molecule found on the surface of neurons.

28 Oct 2020

New technique can detect TDP-43 protein in patients with ALS and frontotemporal dementia

A test to diagnose two very serious diseases such as ALS and FTD when the pathologies have not yet appeared, thereby providing doctors and patients with essential information tools to tackle them early and develop new treatments.

27 Oct 2020

Protein delivery to the testes restores male fertility in mice

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases.

21 Oct 2020

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

It has recently been described that infection by some enteroviruses - a genus of viruses that commonly cause diseases of varying severity - could potentially trigger diabetes, although its direct effect 'in vivo' as well as its mechanism of action at the molecular level were unknown.

21 Oct 2020

Scientists uncover a novel cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin deficiency present with high variation in the severity of liver disease.

21 Oct 2020

Coronavirus pandemic perceived as the greatest health risk

Next on the list of concerns, though notably less frequently mentioned, are unhealthy or wrong diet as well as climate and environmental pollution - these were the most frequently mentioned concerns in February's survey.

20 Oct 2020

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Our immune system's capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65.

20 Oct 2020

Scientists uncover important disease-fighting role for cells in the liver

Scientists at Scripps Research have uncovered an important disease-fighting role for cells called hepatocytes, which constitute most of the liver. The discovery could potentially be harnessed to develop new medicines for viral illnesses.

19 Oct 2020

Plant genetic engineering to sustainably address micronutrient malnutrition

More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

16 Oct 2020

Researchers engineer cow muscle cells to produce plant nutrients

A group of researchers at Tufts University have genetically engineered cow muscle cells to produce plant nutrients not natively found in beef cells.

15 Oct 2020

New position statement clarifies WHO's stance on the use of genetically modified mosquitoes

Each year, more than 700 000 people die from vector-borne diseases (VBDs) such as malaria, dengue, schistosomiasis, leishmaniasis, Chagas disease, yellow fever and Japanese encephalitis, among others.

14 Oct 2020

Cancer-killing T cells release chemicals to direct swarms towards tumors

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

13 Oct 2020

Drug derived from a natural human protein could stop lethal lung damage from the flu

The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.

13 Oct 2020

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

13 Oct 2020

Female mosquitoes can detect a combination of four different substances in blood

Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

A new Center for Precision Animal Modeling, or C-PAM, has been created at the University of Alabama at Birmingham, supported by a five-year, $9.3 million grant from the National Institutes of Health's Office of Research Infrastructure Programs.

9 Oct 2020

Launch of new WHO guidance on ethics and vector-borne diseases

On Wednesday 14 October, WHO will launch new guidance: Ethics & vector-borne diseases. The guidance document is a culmination of more than three years of work and will be a valuable new tool to support global efforts to prevent and control vector-borne diseases (VBDs).

9 Oct 2020

Transplantation of pig hearts may solve chronic shortage of donor organs

The goal of harvesting hearts from pigs to solve the chronic shortage of these donor organs appears to be in reach, according to a new scientific review by researchers at Massachusetts General Hospital (MGH).

9 Oct 2020

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible are reviewed in the peer-reviewed journal Human Gene Therapy.

8 Oct 2020

Researchers have discovered a safe, non-invasive way to manage blood sugar

Researchers from the University of Iowa may have discovered a safe new way to manage blood sugar non-invasively. Exposing diabetic mice to a combination of static electric and magnetic fields for a few hours per day normalizes two major hallmarks of type 2 diabetes, according to new findings published Oct. 6 in Cell Metabolism.

7 Oct 2020

Genetic Engineering News and Research

Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

New technique can detect TDP-43 protein in patients with ALS and frontotemporal dementia

Protein delivery to the testes restores male fertility in mice

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

Scientists uncover a novel cellular mechanism for disposing of misfolded proteins

Coronavirus pandemic perceived as the greatest health risk

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Scientists uncover important disease-fighting role for cells in the liver

Plant genetic engineering to sustainably address micronutrient malnutrition

Researchers engineer cow muscle cells to produce plant nutrients

New position statement clarifies WHO's stance on the use of genetically modified mosquitoes

Cancer-killing T cells release chemicals to direct swarms towards tumors

Drug derived from a natural human protein could stop lethal lung damage from the flu

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Female mosquitoes can detect a combination of four different substances in blood

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

Launch of new WHO guidance on ethics and vector-borne diseases

Transplantation of pig hearts may solve chronic shortage of donor organs

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

Researchers have discovered a safe, non-invasive way to manage blood sugar

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