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COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

In a new study, researchers assessed the efficiency of immunization with a bacterial peptide conjugated to the SARS-CoV-2 receptor-binding domain against SARS-CoV-2 infection.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

The influence of immunosuppressive therapy on the development of adaptive immunity after SARS-CoV-2 vaccination

Researchers evaluated the impact of immunosuppressive therapies on the induction of adaptive immunity after COVID-19 vaccination.

5 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

How does obesity affect the immune system?

A new study summarizes new findings on the immunoregulatory effects of excessive fat stores or malnutrition through Th2 cells.

4 Jul 2022

Enteric viruses found to transmit through the salivary route

Researchers reported on the productive and persistent infection of salivary glands (SGs) by enteric viruses, with oral cavity titers similar to intestinal titers.

4 Jul 2022

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Researchers explored the molecular basis for increased immunity against heterologous SARS-CoV-2 strains after repeated antigen exposures.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

Researchers assessed the impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2.

1 Jul 2022

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.

30 Jun 2022

AAP recommends breastfeeding for 2 years

The American Academy of Pediatrics recommends that mothers to continue breastfeeding for two years or beyond.

30 Jun 2022

Novel universal flu vaccine confers protection against different strains and subtypes of influenza A viruses

A new universal flu vaccine constructed with key parts of the influenza virus offers broad cross protection against different strains and subtypes of influenza A viruses in young and aged populations, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State University.

30 Jun 2022

How to develop an "all-variant" COVID vaccine

In a recent study published in Nature Immunology, researchers summarized their observations of humoral immune responses elicited in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infected people. Additionally, they discussed all the types of SARS-CoV-2 infection- and vaccine-induced neutralizing antibodies (nAbs).

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

COVID-19 pandemic linked to lower antibodies in breastmilk

New research describes the results of a study measuring such protection and exploring the effects of waning antibody levels on infant susceptibility to respiratory pathogens.

29 Jun 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

In a recent study posted to the medRxiv* pre-print server, Canadian researchers evaluated antibody responses in kidney transplant recipients (KTRs) before and one and three months after receiving the third dose of a messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine.

28 Jun 2022

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

In a recent article posted to the medRxiv* preprint server, scientists from Japan assessed the safety and immunogenicity of coronavirus disease 2019 (COVID-19) BNT162b2 vaccine among lung cancer patients under treatment.

28 Jun 2022

Immunoglobulin News and Research

COVID-19 vaccination with bacterial peptide conjugated to receptor-binding domain elicits potent immune response

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Novel inhalable COVID-19 vaccine

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

The influence of immunosuppressive therapy on the development of adaptive immunity after SARS-CoV-2 vaccination

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

How does obesity affect the immune system?

Enteric viruses found to transmit through the salivary route

Somatic hypermutations found to enhance humoral immunity against SARS-CoV-2 variants

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The impact of pre-existing immunity on mRNA booster doses of BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

AAP recommends breastfeeding for 2 years

Novel universal flu vaccine confers protection against different strains and subtypes of influenza A viruses

How to develop an "all-variant" COVID vaccine

Casirivimab/imdevimab improve outcomes in early COVID-19

COVID-19 pandemic linked to lower antibodies in breastmilk

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

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