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'Innovative Research Award' helps CU scientists to explore BRAF inhibition resistance in brain cancer

Cancers used to be defined by where they grow in the body - lung cancer, skin cancer, brain cancer, etc. But work in recent decades has shown that cancers sharing specific genetic changes may have more in common than cancers that happen to grow in an area of the body.

21 Jan 2020

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the presence of B cells, which are powerhouses, in tumor cells, combat the disease from within.

16 Jan 2020

Immune system contribution to tumor heterogeneity may influence liver cancer growth

Researchers at Mount Sinai School of Medicine say the immune system might contribute to the tumor heterogeneity seen in liver cancer that can affect the rate of cancer growth.

15 Jan 2020

Crab study advocates a more 'multimodal' approach to defining cell identity

A longstanding goal in neuroscience is to classify the brain's many cells into discrete categories according to their function.

31 Dec 2019

New spatiomolecular map may advance understanding of the brain's decision-making area

Researchers at Karolinska Institutet have come one step closer toward understanding how the part of our brain that is central for decision-making and the development of addiction is organized on a molecular level.

26 Dec 2019

Immunosupressant combination therapy for glioblastoma shows promise

Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The team also performed studies on human tumours to arrive at their conclusions. The study was published in the latest issue of the journal Nature Medicine this week.

23 Dec 2019

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus.

22 Dec 2019

Nanopores – the key to identifying amino acids in proteins

DNA and RNA sequencing has become the new watchword for the biological researchers, as this tells them exactly what is going on at cellular level in health and disease. However, it is a partial revelation unless we also know what is happening at the level of proteins as well.

19 Dec 2019

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Molecular subtyping of bladder tumors outperformed by standard pathology tests

While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found that sophisticated new subtyping techniques designed to do this provide no better information than long-standing pathology tests.

14 Dec 2019

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Cancer immunology drugs, which harness the body's immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.

9 Dec 2019

Researchers validate RNA sequencing methods using crab's nervous system model

"Being crabby" might have a whole new meaning.

6 Dec 2019

Using genomics to identify promising novel treatment for lymphatic filariasis

Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat.

3 Dec 2019

RNA Sequencing News and Research

'Innovative Research Award' helps CU scientists to explore BRAF inhibition resistance in brain cancer

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

Immune system contribution to tumor heterogeneity may influence liver cancer growth

Crab study advocates a more 'multimodal' approach to defining cell identity

New spatiomolecular map may advance understanding of the brain's decision-making area

Immunosupressant combination therapy for glioblastoma shows promise

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

Nanopores – the key to identifying amino acids in proteins

Scientists develop computationally inspired method for preclinical study of anxiety

Using math equations to detect and forecast liver cancer risk

Molecular subtyping of bladder tumors outperformed by standard pathology tests

Study shows how a new combination approach helps overcome resistance to cancer immunotherapy

Researchers validate RNA sequencing methods using crab's nervous system model

Using genomics to identify promising novel treatment for lymphatic filariasis

Scientists discover new molecular drivers of Parkinson's disease

MIT researchers develop method to isolate T cells primed for certain allergies or infections

Vaping wrecks immune cell function, increases infection risk

Yale-led study provides roadmap to discover new treatment for idiopathic pulmonary fibrosis

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

New method for identifying 'biomarkers' of drug response in triple-negative breast cancer cell lines

Sequencing & Genomics: Elevating Science and Healthcare eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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