UK Biobank News and Research

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HSD3B1 gene holds clues for predicting and treating endometrial cancer

The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding from the Cleveland Clinic's Lerner Research Institute.

13 Sep 2022

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Researchers have, for the first time, systematically estimated the impact of a range of different disease-associated genetic risk factors on the loss of healthy life years. Knowing the contribution of different genetic risk factors on disease burden can help prioritise and design interventions using genetic information.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

In a recent study published in the journal BMJ Open, researchers investigated the impact of folic acid supplements and methotrexate, in combination or individually, on disease severity and mortality in coronavirus disease 2019 (COVID-19) cases.

8 Sep 2022

Greater physical activity, lower sedentary time likely to reduce breast cancer risk

Boosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to strengthen proof of causation and published online in the British Journal of Sports Medicine.

7 Sep 2022

Inhaled glucocorticoids linked to changes in brain matter

A recent BMJ Open study conducted a cross-sectional analysis to test the hypothesis that the usage of systemic and inhaled glucocorticoids was associated with alterations in grey matter volume (GMV) and white matter microstructure.

5 Sep 2022

Higher tea intake linked with modestly lower risk of death

A prospective study of half a million tea drinkers in the United Kingdom has shown that higher tea intake was associated with a modestly lowered risk of death.

29 Aug 2022

Performing moderate or vigorous physical activity may lower the risk of heart failure

A six-year analysis of more than 94,000 adults in the U.K. Biobank with no history of heart failure at enrollment has found that engaging in moderate or vigorous physical activity may lower the risk of developing heart failure, according to new research published today in the American Heart Association's flagship journal Circulation.

29 Aug 2022

Study finds a low n-3 fatty acid status was associated with increased risk for hospitalization with COVID-19

Researchers explored the association between COVID-19 risk and blood N-3 fatty acid levels.

25 Aug 2022

Consumption of ultra-processed foods increases risk of COVID-19

Researchers explore the association between consumption of ultra-processed foods and risk of SARS-CoV-2 infection.

21 Aug 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Inflammation is an essential part of the body's healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, and autoimmune diseases.

8 Aug 2022

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

In a new study, researchers assessed the genetic variation among targets of Alzheimer's disease risk and anti-diabetic drugs.

3 Aug 2022

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

Socioeconomic deprivation, including neighborhood disadvantages and persistent low wages, are associated with higher dementia risk, lower cognitive performance and faster memory decline, according to several studies reported today at the Alzheimer’s Association International Conference 2022 in San Diego and virtually.

2 Aug 2022

People who eat more ultra-processed foods may have higher risk of dementia

People who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developing dementia than those who eat the lowest amounts, according to a new study published in the July 27, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

27 Jul 2022

UK Biobank News and Research

HSD3B1 gene holds clues for predicting and treating endometrial cancer

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Pollutant particles in the air trigger lung cancer in non-smokers

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

Greater physical activity, lower sedentary time likely to reduce breast cancer risk

Inhaled glucocorticoids linked to changes in brain matter

Higher tea intake linked with modestly lower risk of death

Performing moderate or vigorous physical activity may lower the risk of heart failure

Study finds a low n-3 fatty acid status was associated with increased risk for hospitalization with COVID-19

Consumption of ultra-processed foods increases risk of COVID-19

Research suggests a new model of how beige fat biogenesis is controlled

Novel AI tools accurately predict the role of DNA’s regulatory elements

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Socioeconomic deprivation associated with increased dementia risk and faster memory decline

People who eat more ultra-processed foods may have higher risk of dementia

Researchers assess UK biobank genome sequences

Scientists provide first report from the largest whole genome sequencing effort to date

Study links low vitamin D level with risk of dementia

Coffee consumption during pregnancy may not be harmful

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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