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Can platelet size predict severity and mortality in COVID-19?

The ongoing COVID-19 pandemic has baffled researchers with its propensity to cause symptoms of largely unpredictable severity in the affected individuals. An exciting new study reports on the potential predictive value of platelet size in this situation. COVID-19 patients with severe disease often develop clots in vital organs, which leads to further complications. It is known that platelet size is a good indicator of activation.

22 Jul 2021

Study: Omega-3 levels in blood erythrocytes are good mortality risk predictors

Levels of omega-3 fatty acids in the blood are as good a predictor of mortality from any cause as smoking, according to a study involving the Hospital del Mar Medical Research Institute (IMIM), in collaboration with The Fatty Acid Research Institute in the United States and several universities in the United States and Canada.

22 Jul 2021

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published.

22 Jul 2021

Professional rugby participation may be linked with structural changes in the brain

Participation in elite adult rugby may be associated with changes in brain structure.

22 Jul 2021

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

Some of these variants, known as variants of concern (VoC), have a much higher rate of transmission and increased mortality than the original SARS-CoV-2 strain. Therefore, it is imperative to assess the efficacy of the available vaccines against the circulating SARS-CoV-2 strains. In addition, tracking the continuously evolving genetic variants is also vital to prevent future outbreaks.

22 Jul 2021

Study finds strong interconnection between toxic pollution and climate risks to human health

For more than 30 years, scientists on the U.N.'s Intergovernmental Panel on Climate Change have focused on human-induced climate change.

21 Jul 2021

Experts develop consensus statement to help improve long-term well-being of people with HIV

Since antiretroviral therapy (ART) for HIV was introduced in 1996, AIDS-related morbidity and mortality has declined significantly.

21 Jul 2021

Global consortium publishes findings on all-cause mortality during COVID-19 pandemic in 22 countries

A global consortium representing 27 institutions has published findings comparing mortality in the previous five years to deaths between January and August 2020 in the first wave of the pandemic.

21 Jul 2021

U.S. sees sharp decrease in life expectancy largely due to COVID-19 pandemic, CDC says

New preliminary data from the United States Centers for Disease Control and Prevention (CDC) suggests that average life expectancy in the United States fell by 1.5 years over 2020.

21 Jul 2021

COVIDcast API: An open repository of real-time COVID-19 indicators

A new preprint available on the medRxiv* server reports the utility of the COVIDcast API, a database of all COVID-19 indicators that are constantly being updated, dating from April 2020.

21 Jul 2021

$Cognitive decline increases future fracture risk in women$

Cognitive decline increases future fracture risk in women

Researchers led by the Garvan Institute of Medical Research have discovered a link between cognitive decline and a faster rate of bone loss, and found that cognitive decline over five years increased future fracture risk in women. The association between cognitive decline and bone loss was weaker in men.

21 Jul 2021

Study examines clinical outcomes in vaccinated individuals hospitalized with SARS-CoV-2 Delta variant

A new study has been published on the medRxiv* preprint server that has evaluated the clinical outcomes of the COVID-19 patients hospitalized in AIG hospitals, Hyderabad, India, between April 24, 2021, and May 31, 2021.

20 Jul 2021

COVID-19 vaccination in New York City reduces hospital admissions and deaths

A new study, released as a preprint on the medRxiv* server, shows how the successful rollout of effective COVID-19 vaccines in this metropolis led to the dramatic reduction in the number of cases with moderate to severe coronavirus disease 2019 (COVID-19) and curbed COVID-19-related mortality.

20 Jul 2021

Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

RedHill Biopharma Ltd., a specialty pharma company that is a leader in the development of novel oral therapies for COVID-19, today announced that all treatment and follow-up has now been completed in the 475-patient global Phase 2/3 study with opaganib (ABC294640) in patients hospitalized with severe COVID-19 pneumonia (NCT04467840). Top-line results are expected in the coming weeks.

20 Jul 2021

Exhausted T cells linked to increased risk of COVID-19 mortality

New research led by Nadia R. Roan of Gladstone Institutes and the University of California, San Francisco, finds a correlation between high numbers of inflammatory CXCR4+ T cells and regulatory T cells specific to SARS-CoV-2 and dying from infection. In contrast, people who recovered from severe COVID-19 illness were more likely to have many SARS-CoV-2-specific T cells that perform homeostatic proliferation.

20 Jul 2021

Thai study looks at CoronaVac vaccine vs. natural immunity to SARS-COV-2 variants

A new study evaluates the efficacy of vaccine- and infection-induced antibodies against SARS-CoV-2 variants.

19 Jul 2021

VBL team receives $100,000 award to track abdominal aortic aneurysms

The Vascular Bioengineering Lab at the University of Pittsburgh's Swanson School of Engineering seeks to understand and develop solutions to the causes and effects of disease in tubular tissue and organs.

19 Jul 2021

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

19 Jul 2021

Study reveals pathological mechanism and treatment strategy of pre-engraftment syndrome

The research team led by Prof. WEI Haiming and Prof. TIAN Zhigang from Division of Life Sciences and Medicine, University of Science and Technology of China of the Chinese Academy of Sciences, collaborating with the research group led by Prof. SUN Zimin from the First Affiliated Hospital of USTC revealed the pathological mechanism of severe pre-engraftment syndrome (PES) after umbilical cord blood transplantation, not only providing a treatment strategy for patients with PES, but significantly guiding for further improvement in the curative effect of unrelated cord blood transplantation (UCBT).

19 Jul 2021

Study suggests children develop short-term humoral immunity following SARS-CoV-2 infection

A single-center, cross-sectional epidemiological survey conducted in Israel has recently pointed out that antibodies induced by natural SARS-CoV-2 infection in children start declining just after 4 months of acute infection. However, their seropositivity rates are not impacted by school reopening. The study has recently been published in the journal Acta Paediatrica.

19 Jul 2021

Mortality News and Research

Can platelet size predict severity and mortality in COVID-19?

Study: Omega-3 levels in blood erythrocytes are good mortality risk predictors

Investigational antipsychotic treatment offers sustained benefits for people with dementia-related psychosis

Professional rugby participation may be linked with structural changes in the brain

SARS-CoV-2 genomic surveillance identifies intricacies of stabilizing vs. destabilizing mutations

Study finds strong interconnection between toxic pollution and climate risks to human health

Experts develop consensus statement to help improve long-term well-being of people with HIV

Global consortium publishes findings on all-cause mortality during COVID-19 pandemic in 22 countries

U.S. sees sharp decrease in life expectancy largely due to COVID-19 pandemic, CDC says

COVIDcast API: An open repository of real-time COVID-19 indicators

Cognitive decline increases future fracture risk in women

Study examines clinical outcomes in vaccinated individuals hospitalized with SARS-CoV-2 Delta variant

COVID-19 vaccination in New York City reduces hospital admissions and deaths

Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

Exhausted T cells linked to increased risk of COVID-19 mortality

Thai study looks at CoronaVac vaccine vs. natural immunity to SARS-COV-2 variants

VBL team receives $100,000 award to track abdominal aortic aneurysms

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

Study reveals pathological mechanism and treatment strategy of pre-engraftment syndrome

Study suggests children develop short-term humoral immunity following SARS-CoV-2 infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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