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Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Isis Pharmaceuticals, Inc. today announced that its partner, Biogen, has initiated a Phase 1/2 clinical study of ISIS-SOD1 Rx (BIIB067) in patients with amyotrophic lateral sclerosis (ALS).

11 Dec 2015

Apigenin improves neuron formation, strengthens connections between brain cells

Brazilian researchers from D'Or Institute for Research and Education, Federal University of Rio de Janeiro and Federal University of Bahia have demonstrated in laboratory that apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells.

11 Dec 2015

LSD reduces connectivity within human brain networks

LSD is known to cause changes in consciousness, including "ego-dissolution", or a loss of the sense of self. Despite a detailed knowledge of the action of LSD at specific serotonin receptors, it has not been understood how this these pharmacological effects can translate into such a profound effect on consciousness.

11 Dec 2015

DZNE molecular biologist to receive Gottfried Wilhelm Leibniz Prize for research on neurons

The molecular biologist Frank Bradke (46), group leader at the German Center for Neurodegenerative Diseases (DZNE) and professor for neurobiology at the University of Bonn, will be awarded the "Gottfried Wilhelm Leibniz Prize", which is endowed with 2.5 million euros.

11 Dec 2015

Shank3 gene linked to both autism and schizophrenia

Although it is known that psychiatric disorders have a strong genetic component, untangling the web of genes contributing to each disease is a daunting task. Scientists have found hundreds of genes that are mutated in patients with disorders such as autism, but each patient usually has only a handful of these variations.

10 Dec 2015

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Circuit Therapeutics today announced that it has been awarded a 2.7 million dollar contract from the Defense Advanced Research Projects Agency to pursue optogenetic therapies for peripheral nervous system indications. The award, part of DARPA's Electrical Prescriptions (ElectRX) program, will enable Circuit to pursue research and development projects related to its treatment for neuropathic pain.

10 Dec 2015

Researchers identify brain processes in mice that shape different sensory perceptions

Scientists have long known that when sounds are faint or objects are seen through fog in the distance, repetition of these weak or ambiguous sensory “inputs” can result in different perceptions inside the same brain.

10 Dec 2015

Researchers use mathematical models to study brain cells essential for correct functioning of neurons

Applying mathematical models used for studying the galaxies or interactions between elementary particles, researchers at the Institute of Neuroscience of the Universitat Autònoma de Barcelona, in collaboration with Massachusetts General Hospital, Boston, have analysed the spatial distribution of astrocytes: brain cells that are essential for the correct functioning of neurons.

10 Dec 2015

UC San Diego researchers awarded MJFF grant to identify biomarkers for Parkinson's disease

Parkinson's disease is difficult to diagnose, particularly in its early stages. Now, researchers at University of California, San Diego School of Medicine - aided by a $375,000 grant from The Michael J. Fox Foundation for Parkinson's Research - hope to improve the prospects of early diagnosis by identifying a biological signpost in the blood.

9 Dec 2015

Harvard's Kevin Staley honored with AES Research Recognition Award for Basic Science

The American Epilepsy Society announces that Kevin Staley, M.D., professor of child neurology and mental retardation at Harvard Medical School and chief of pediatric neurology at Massachusetts General Hospital, is being honored with the AES Research Recognition Award for Basic Science at the Society's 69th annual meeting in Philadelphia.

8 Dec 2015

New algorithm helps analyze microscope images of cells growing in petri dishes

Scientists looking for ways to stimulate the growth of neurons can spend hours painstakingly analyzing microscope images of cells growing in petri dishes. A new algorithm developed by Brown University researchers automates that process and analyzes images more accurately than previous automated approaches.

8 Dec 2015

UB researchers develop a way to ramp up conversion of skin cells into dopamine neurons

For decades, the elusive holy grail in Parkinson's disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield.

8 Dec 2015

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

BMBF, US-American National Institute of Health invest over 900,000 euros in memory research

Investing more than 900,000 euros, the German Federal Ministry of Education and Research and the US-American National Institute of Health are funding a close research cooperation between Prof Dr Sen Cheng from the Mercator Research Group "Structure of Memory" at the Ruhr-Universität Bochum and Prof Dr Kamran Diba from the University of Wisconsin-Milwaukee.

1 Dec 2015

Low levels of BRCA1 protein in the brain linked to dementia

Mutant forms of breast cancer factor 1 (BRCA1) are associated with breast and ovarian cancers but according to new findings, in the brain the normal BRCA1 gene product may also be linked to Alzheimer's disease. The results, published in Nature Communications, suggest that low levels of BRCA1 protein in the brain may contribute to dementia.

1 Dec 2015

BRCA1 depletion can potentially contribute to cognitive deficits in Alzheimer's disease

Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease.

30 Nov 2015

Concussed athletes in clinical recovery experience neurophysiological abnormalities

Some athletes who experience sports-related concussions have reduced blood flow in parts of their brains even after clinical recovery, according to a study presented today at the annual meeting of the Radiological Society of North America.

30 Nov 2015

Discovery opens up new avenue for research on potential treatments for Alzheimer's disease

A team of researchers led by UNSW Australia scientists has discovered how connections between brain cells are destroyed in the early stages of Alzheimer's disease - work that opens up a new avenue for research on possible treatments for the degenerative brain condition.

27 Nov 2015

Physical exercise can enhance development of new brain cells

Exercise can enhance the development of new brain cells in the adult brain, a process called adult neurogenesis. These newborn brain cells play an important role in learning and memory. A new study has determined that mice that spent time running on wheels not only developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects from familiar objects.

25 Nov 2015

Slower aging reduces degeneration related to Parkinson's disease

Humans have long sought to reduce the effects of aging. Now, there may be another reason to continue searching for ways to slow the clock--preventing Parkinson's disease.

25 Nov 2015

Neurons News and Research

Biogen begins ISIS-SOD1 Rx Phase 1/2 clinical study in patients with amyotrophic lateral sclerosis

Apigenin improves neuron formation, strengthens connections between brain cells

LSD reduces connectivity within human brain networks

DZNE molecular biologist to receive Gottfried Wilhelm Leibniz Prize for research on neurons

Shank3 gene linked to both autism and schizophrenia

Circuit awarded contract to pursue optogenetic therapies for peripheral nervous system indications

Researchers identify brain processes in mice that shape different sensory perceptions

Researchers use mathematical models to study brain cells essential for correct functioning of neurons

UC San Diego researchers awarded MJFF grant to identify biomarkers for Parkinson's disease

Harvard's Kevin Staley honored with AES Research Recognition Award for Basic Science

New algorithm helps analyze microscope images of cells growing in petri dishes

UB researchers develop a way to ramp up conversion of skin cells into dopamine neurons

Existing compound offers hope for slowing Huntington's disease progression

BMBF, US-American National Institute of Health invest over 900,000 euros in memory research

Low levels of BRCA1 protein in the brain linked to dementia

BRCA1 depletion can potentially contribute to cognitive deficits in Alzheimer's disease

Concussed athletes in clinical recovery experience neurophysiological abnormalities

Discovery opens up new avenue for research on potential treatments for Alzheimer's disease

Physical exercise can enhance development of new brain cells

Slower aging reduces degeneration related to Parkinson's disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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