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Stapled Peptides directly inhibit the Notch transcription factor complex

Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collaborators, James E. Bradner, MD of the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and Gregory L. Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, “Direct Inhibition of the Notch Transcription Factor Complex.”

12 Nov 2009

Stapled Peptides can inhibit key intracellular biological targets, says new research

Aileron Therapeutics, a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides, announced today that its collaborators, James E. Bradner, MD of the Dana-Farber Cancer Institute and the Broad Institute of Harvard and MIT, and Gregory L. Verdine, PhD, Professor of Chemistry at Harvard University, published research in Nature entitled, "Direct Inhibition of the Notch Transcription Factor Complex." Results presented in the paper showed that Stapled Peptides can potently and directly inhibit the transcription factor Notch, an oncogene implicated in cancer cell proliferation and survival.

12 Nov 2009

Glissandra Skincare launches three signature anti-aging products

Glissandra™ Skincare Inc. announced the global launch of its three signature anti-aging products concurrent with the Israel Cancer Research Fund’s “Women of Action” awards luncheon honoring Beverly Cohen, Lisi Harrison, and Vivien Zighelboim, Ph.D, at the Four Seasons Hotel, Los Angeles at Beverly Hills.

11 Nov 2009

Healthpoint to launch ULTRACEPT Antiseptic Handwash

A new antiseptic handwash, based on a formula previously used only by surgeons and other clinicians, will soon be available to consumers and provides up to six hours of prolonged germ kill with repeated use.

11 Nov 2009

New organic herbal products to help support body's immune system

Gaia Herbs, a leading grower and manufacturer of natural and organic herbal products, announces Quick Defense Liquid Phyto-Caps, a combination of high potency organic Echinacea, organic Elderberry, organic Ginger and Andrographis that helps support the body's immune system at onset.

10 Nov 2009

"Point of Care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads" report from MarketResearch.com

MarketResearch.com has announced the addition of Kalorama Information's new report "Point of Care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads," to their collection of In Vitro Diagnostics market reports.

10 Nov 2009

Three IVF attempts increase chances of a live birth

Just one in three women gives birth after a single IVF attempt, but the cumulative chance of a live birth increases with each cycle - where women are offered three cycles nearly two thirds go on to have babies, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg in Sweden.

10 Nov 2009

EpiCept announces third quarter 2009 financial results

EpiCept Corporation today announced operating and financial results for the three and nine months ended September 30, 2009, and provided an update on Ceplene® and several of the Company’s key product candidates.

10 Nov 2009

CRINONE vaginal progesterone gel as effective as IM progesterone for luteal phase support in IVF-ET

In their American Society of Reproductive Medicine (ASRM) conference wrap-up, Medscape highlighted the article published by them on October 27, 2009, which summarized the results from the largest prospective, randomized clinical study to compare vaginal progesterone to intramuscular progesterone injections (IM progesterone) for luteal support in infertility treatment.

9 Nov 2009

Chinese SFDA approves China Medical Technologies' Leukemia BCR/ABL fusion gene detection FISH Probe

China Medical Technologies, Inc., a leading China-based medical device company that develops, manufactures and markets advanced in-vitro diagnostic products, today announced that the Company has received approval for its Leukemia BCR/ABL fusion gene detection FISH Probe (the "Leukemia BCR/ABL FISH Probe") from the State Food and Drug Administration of China (the "SFDA").

9 Nov 2009

Caliper Life Sciences announces financial results for third quarter ended September 30, 2009

Caliper Life Sciences, Inc. today reported results for its third quarter ended September 30, 2009. GAAP revenues increased by 4% to $32.2 million, from non-GAAP revenues of $31.0 million in the same period of 2008, which represents GAAP revenue of $34.0 million in the third quarter of 2008 reduced by $3.0 million for the impact of divested product lines.

9 Nov 2009

Caliper Discovery Alliances and Services receives a $1.8M funding commitment for the EPA's ToxCast program

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today announced that its Caliper Discovery Alliances and Services (CDAS) unit has been awarded a new funding commitment for $1.8 million under its contract with the Environmental Protection Agency (EPA) for the EPA's ToxCast screening program.

9 Nov 2009

Swedish study: Chances of having a baby increases over three cycles

9 Nov 2009

New micronail chip to enable electronics and biological cells communicate with each other

IMEC presents a unique microchip with microscopic nail structures that enable close communication between the electronics and biological cells. The new chip is a mass-producible, easy-to-use tool in electrophysiology research, for example for fundamental research on the functioning and dysfunctioning of the brain. Each micronail structure serves as a close contact-point for one cell, and contains an electrode that can very accurately record and trigger in real-time the electrical activity of an individual electrogenic cell in a network.

9 Nov 2009

Cardinal Rigali to support health care bill if an amendment preserving the status quo for abortion is voted upon

American Life League president Judie Brown released the following statement on the news that Cardinal Justin Rigali will support Speaker Nancy Pelosi's Affordable Health Care for America Act (H.R. 3962), provided an amendment preserving the status quo for abortion is voted upon.

9 Nov 2009

Third-quarter 2009 financial results announced by Inhibitex

Inhibitex, Inc., today announced its financial results for the third quarter ended September 30, 2009. The Company held cash, cash equivalents and short-term investments of $21.1 million at September 30, 2009, as compared to $33.1 million at December 31, 2008.

6 Nov 2009

Cellumen's Rat Hepatocyte Early Safety Assessment Panel increases predictivity for human DILI

Cellumen, Inc., a discovery and early safety assessment company, today announced that its in vitro Rat Hepatocyte Early Safety Assessment Panel provides increased predictivity for human drug induced liver injury (DILI) equivalent to that of a recently published panel comprised of human hepatocytes. The implications of this study have a significant impact on cost and throughput for in vitro human DILI predictive solutions.

6 Nov 2009

in vitro News and Research

Stapled Peptides directly inhibit the Notch transcription factor complex

Stapled Peptides can inhibit key intracellular biological targets, says new research

Glissandra Skincare launches three signature anti-aging products

Healthpoint to launch ULTRACEPT Antiseptic Handwash

New organic herbal products to help support body's immune system

"Point of Care Diagnostics 2010 and Beyond: Rapid Testing at a Crossroads" report from MarketResearch.com

Three IVF attempts increase chances of a live birth

EpiCept announces third quarter 2009 financial results

CRINONE vaginal progesterone gel as effective as IM progesterone for luteal phase support in IVF-ET

Chinese SFDA approves China Medical Technologies' Leukemia BCR/ABL fusion gene detection FISH Probe

Caliper Life Sciences announces financial results for third quarter ended September 30, 2009

Caliper Discovery Alliances and Services receives a $1.8M funding commitment for the EPA's ToxCast program

Swedish study: Chances of having a baby increases over three cycles

New micronail chip to enable electronics and biological cells communicate with each other

Cardinal Rigali to support health care bill if an amendment preserving the status quo for abortion is voted upon

Third-quarter 2009 financial results announced by Inhibitex

Cellumen's Rat Hepatocyte Early Safety Assessment Panel increases predictivity for human DILI

Columbia Laboratories reports net revenues of $7.9 million for third quarter 2009

Scientists differentiate human embryonic stem cells into lung epithelial tissue using air-liquid interface

Micro-injector may help rapid development of new generation of drugs

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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