Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Rheumatoid arthritis linked to excess risk of congestive heart failure

A serious chronic disease, rheumatoid arthritis (RA) is characterized by inflammation and damage of the joint, major organ involvement and increased mortality. Among patients, about one in three deaths results from cardiovascular disease (conditions affecting the heart or blood vessels).

3 Feb 2005

New understanding of the causes for symptoms of sickle cell disease

A new understanding of the causes for symptoms of sickle cell disease, a condition affecting one in every 600 African-Americans, has resulted from a study by researchers at Duke University Medical Center and Howard Hughes Medical Institute (HHMI). Their findings may lead to a new, more direct method for treating the disease, they said.

31 Jan 2005

Viagra protects cardiomyocytes against cell death

Virginia Commonwealth University researchers have shown that a widely used drug for treating erectile dysfunction, Viagra, reduces the death of heart cells under heart attack-like conditions in a laboratory model.

31 Jan 2005

No association between a herpesvirus infection and pulmonary hypertension

Contrary to the results of a recent U.S. study, investigators in Japan found no association between a herpesvirus infection and a potentially life-threatening form of high blood pressure, as reported in the March 1 issue of The Journal of Infectious Diseases, now available online.

30 Jan 2005

Stem cells given in minimally invasive procedure improve heart function

Patients with severe congestive heart failure who had exhausted all other treatment options showed markedly improved heart function following a procedure in which their own stem cells were deployed directly into the heart by way of four tiny incisions in the chest, according to results of a trial presented today at the 41st Annual Meeting of the Society for Thoracic Surgery.

26 Jan 2005

Genetic defect leads to electrical instability and mechanical pump failure

In genetic mapping of a large family with several members affected by a type of heart failure called dilated cardiomyopathy (DCM), the Mayo Clinic team found a defect in a gene on chromosome 3 called SCN5A.

26 Jan 2005

Basic biochemical composition of heart valves in patients with congestive heart failure are markedly different than those with healthy hearts

Surprising new findings in the Journal of the American College of Cardiology show that the basic biochemical composition of heart valves in patients with congestive heart failure are markedly different than those with healthy hearts, a finding that may explain the mixed success of surgery to repair valve dysfunction in these patients.

25 Jan 2005

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

Physicians are challenged in treating heart patients who may be at high-risk for gastrointestinal bleeding from aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Factors that place patients at high-risk include a history of ulcers or gastrointestinal complications such as bleeding, increased age and congestive heart failure.

20 Jan 2005

Clopidogrel (Plavix®) responses appear normal in largest data set

Although individual patients respond differently to treatment with the anti-platelet medication clopidogrel (brand name Plavix®), those variations appear normal and may not indicate important differences in the effectiveness of treatment, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

New research centre for the treatment and prevention of cardiovascular disease

Cardiovascular disease is one of the biggest contributors to the global burden of disease, and by 2020 will be the number one contributor according to figures from the World Health Organisation. In response, the International Centre for Circulatory Health (ICCH) has been set up by Imperial College London and St Mary’s NHS Trust as an international research centre to develop new treatments and preventative strategies for cardiovascular disease around the world.

19 Jan 2005

Rotary blood pump shows promise for pediatric patients

Ventricular assist devices (VADs), blood pumps used in heart failure situations, now have the potential for use in additional patient groups. Scientists and clinicians gathered at the 11th Congress of the International Society of Rotary Blood Pumps in Germany last year to discuss past lessons learned and future directions for this technology.

10 Jan 2005

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

5 Jan 2005

Stem cells from umbilical cord blood effectively treated heart attacks

When injected into rats' hearts soon after a heart attack, stem cells taken from human umbilical cord blood (HUCB) greatly reduced the size of heart damage and restored pumping function to near normal. This improvement occurred without the need for drugs to prevent the rats' immune system from rejecting the human cells.

5 Jan 2005

May soon be possible to identify people at risk and even to treat a heart problem with a drug that works on the brain

Sudden cardiac death from emotional stress may be triggered by uneven signals from the brain to the heart, according to a study by University College London (UCL) scientists published in the January issue of Brain.

23 Dec 2004

Biological clock affects the patterns of heart-rate control in healthy individuals

In a newly reported, first-ever finding, physicists from Boston University and physiologists from Boston’s Brigham and Women’s Hospital (BWH) have found that the body’s biological clock affects the patterns of heart-rate control in healthy individuals independent of sleep/wake cycle or other behavior influences.

21 Dec 2004

Living alone, financial difficulties, excessive use of alcohol associated with the onset of depression among outpatients with heart failure

Living alone, financial difficulties, excessive use of alcohol and poor results on a heart failure questionnaire were associated with the onset of depression among outpatients with heart failure, according to a new study in the Dec. 21, 2004 issue of the Journal of the American College of Cardiology.

21 Dec 2004

Clinical care of community-dwelling older adults with advanced chronic diseases would be enhanced by identifying and alleviating the range of symptoms they experience

In a study to determine the prevalence of a range of symptoms among older persons living independently with advanced chronic diseases, researchers at Yale have found that the majority experienced multiple moderate or severe symptoms.

8 Dec 2004

Leg wounds can be accurately assessed using photographs taken at a patient's home

A pilot study has shown that leg wounds can be accurately assessed using photographs taken at a patient's home, adding one more example to a growing list of medical conditions that can be successfully monitored remotely.

8 Dec 2004

Resveratrol antioxidant found in red wine may benefit heart tissue

New research on rat heart cells suggests that a well-known antioxidant found in red wine, called resveratrol, may benefit heart tissue by limiting the effects of a condition called cardiac fibrosis.

8 Dec 2004

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

University of Rochester scientists studying a vital protein called Serum Response Factor (SRF) in mice have learned new and unexpected facts about SRF's role in early cardiovascular development, and how a defect in this gene may be an underlying cause in human miscarriages.

8 Dec 2004

Heart Failure News and Research

Further Reading

Rheumatoid arthritis linked to excess risk of congestive heart failure

New understanding of the causes for symptoms of sickle cell disease

Viagra protects cardiomyocytes against cell death

No association between a herpesvirus infection and pulmonary hypertension

Stem cells given in minimally invasive procedure improve heart function

Genetic defect leads to electrical instability and mechanical pump failure

Basic biochemical composition of heart valves in patients with congestive heart failure are markedly different than those with healthy hearts

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

Clopidogrel (Plavix®) responses appear normal in largest data set

New research centre for the treatment and prevention of cardiovascular disease

Rotary blood pump shows promise for pediatric patients

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Stem cells from umbilical cord blood effectively treated heart attacks

May soon be possible to identify people at risk and even to treat a heart problem with a drug that works on the brain

Biological clock affects the patterns of heart-rate control in healthy individuals

Living alone, financial difficulties, excessive use of alcohol associated with the onset of depression among outpatients with heart failure

Clinical care of community-dwelling older adults with advanced chronic diseases would be enhanced by identifying and alleviating the range of symptoms they experience

Leg wounds can be accurately assessed using photographs taken at a patient's home

Resveratrol antioxidant found in red wine may benefit heart tissue

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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