Allodynia News and Research

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Allodynia, meaning "other pain", is a painful (noxious) response to a usually non-painful (innocuous) stimulus and can be either static or mechanical. Allodynia differs from referred pain, but can occur in areas other than the one stimulated. It is dysesthetic. Allodynia is different from hyperalgesia, an extreme reaction to a stimulus which is normally painful.

Common migraine pain condition allodynia also prevalent in cluster headache

A pain condition common in people with migraines also has a high prevalence in patients with cluster headache, according to a study conducted by researchers at the Jefferson Headache Center at Jefferson Hospital for Neuroscience.

27 May 2009

KAI Pharmaceuticals reports positive results for KAI-1678 in pain reduction

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced preclinical results demonstrating the effectiveness of KAI-1678 in reversing pain (hyperalgesia and allodynia) in multiple preclinical models.

19 Nov 2008

MRI reveals relationship between depression and pain

The brains of individuals with major depressive disorder appear to react more strongly when anticipating pain and also display altered functioning of the neural network that modifies pain sensitivity, according to a report in the November issue of Archives of General Psychiatry , one of the JAMA/Archives journals.

4 Nov 2008

Migraine exacerbates skin sensitivity or pain

People with migraine are more likely to experience exacerbated skin sensitivity or pain after non-painful daily activities such as rubbing one's head, combing one's hair and wearing necklaces or earrings, compared to people with other types of headache, according to a study published in the April 22, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

21 Apr 2008

Migraine sufferers found to have brain differences

According to new research from the U.S., migraine sufferers have structural differences in the part of the brain that deals with pain.

20 Nov 2007

People with migraines have differences in cortex area of the brain

People with migraines have differences in an area of the brain that helps process sensory information, including pain, according to a study published in the November 20, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

19 Nov 2007

Why the cold hurts - research has implications for pain relief

Freeing knotted shoelaces with fingers that are frozen stiff is extremely difficult and can even be painful.

20 Jun 2007

Hearing protein TRPA1 also involved with pain perception

The same protein that “translates” sound into nerve signals to the brain and enables individuals to hear is also required for pain perception, researchers from Northwestern University Feinberg School of Medicine have found.

21 Jul 2005

Stronger version of chickenpox vaccine cuts incidence and severity of shingles in older adults

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons who got the disease. The findings appear in the June 2 issue of The New England Journal of Medicine.

1 Jun 2005