Otolaryngology News and Research

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The medical discipline and practice of otolaryngology is a specialty that addresses conditions of the ears, nose, and throat. Another name for this practice is otolaryngology head and neck surgery.

Hearing problems among newly arrived immigrants and language acquisition challenges

Among newly arrived immigrants studying Swedish, 17 percent reported problems hearing conversations.

10 May 2025

Immunotherapy before and after surgery boost longer event-free survival in head and neck cancer

Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3 clinical trial led by investigators from Dana-Farber Brigham Cancer Center and Washington University School of Medicine in St. Louis.

6 May 2025

Pre and post-surgical immunotherapy improves survival in head and neck cancer patients

27 Apr 2025

IL-12 cytokine factory demonstrates success in targeting hard-to-treat cancers

A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable "cytokine factory" that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, pancreatic and colorectal tumors.

8 Apr 2025

Scientists discover key genes for regenerating cells in the ear and eye

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the National Academy of Sciences (PNAS).

1 Apr 2025

Terahertz imaging reveals cochlear structures with high resolution

Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions, this technology opens new possibilities for diagnosing hearing loss and other conditions.

27 Mar 2025

New clinical trial tests 3D-printed devices for treating tracheobronchomalacia in infants

A new clinical trial will allow researchers to study 3D-printed bioresorbable devices aimed at treating children with rare and life-threatening airway condition tracheobronchomalacia.

6 Mar 2025

Oxytocin’s new role in delaying embryo development revealed

Oxytocin, a hormone already known for its role in childbirth, milk release, and mother-infant bonding, may have a newfound purpose in mammalian reproduction.

5 Mar 2025

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high proportion of complete or partial success.

4 Mar 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

New imaging tool reveals the brain's role in cochlea sensitivity

The brain may play a role in helping the ear regulate its sensitivity to sound and compensate for hearing loss by sending a signal to a structure in the inner ear known as the cochlea, according to a study that was just published in the Journal of Neuroscience.

24 Feb 2025

GLP-1RA initiation linked to new thyroid cancer diagnoses

Researchers investigate the risk of incident thyroid cancer among patients treated with glucagon-like peptide-1 receptor agonists.

28 Jan 2025

Surgery reduces accident risk in sleep apnea patients

Sleepiness at the wheel is a significant contributing factor to motor vehicle accidents. A new analysis published in Otolaryngology–Head and Neck Surgery reveals that for people with sleep apnea, getting surgery for their condition may lessen their risk of such accidents compared with using a Continuous Positive Airway Pressure (CPAP) device at night or receiving no treatment.

22 Jan 2025

University of Plymouth partners with IOE to offer global osteopathy training

The University of Plymouth and International Osteopathic Education (IOE) have formed a new partnership that will offer first-class training to aspiring osteopaths from across the world.

7 Jan 2025

Ancient brain circuit stabilizes gaze during movement in early development

An ancient brain circuit, which enables the eyes to reflexively rotate up as the body tilts down, tunes itself early in life as an animal develops, a new study finds.

2 Jan 2025

Public awareness and HPV vaccination rates remain low among American adults

The human papillomavirus (HPV), a common sexually transmitted infection, accounts for 70% of all throat cancers, according to the National Cancer Institute.

10 Dec 2024

Vanderbilt University Medical Center receives $7 million to study breathing tube size in critical care

Vanderbilt University Medical Center has been approved for $7 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) to study the effect of breathing tube size on breathing, speaking and swallowing after critical illness.

6 Dec 2024

Researchers aim to uncover causes of acquired hearing loss and find potential therapies

With a new five-year, $3.2 million grant from the National Institute on Deafness and Other Communications Disorders, researchers at Case Western Reserve University and Mass Eye and Ear will study what causes acquired hearing loss (AHL) and seek new ways to protect against it.

3 Dec 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Oral medication sodium oxybate shows promise for treating laryngeal dystonia

Laryngeal dystonia (LD), a rare neurological disease that significantly impacts a person's ability to speak due to uncontrollable vocal cord spasms, can have a debilitating effect on a person's social life, employment and mental health.

20 Nov 2024