Single Nucleotide Polymorphism News and Research

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Study identifies specific genetic variants that affect the skeletal form and ties a major evolutionary facet of human anatomical change to pathogenesis

Researchers evaluate imaging information and characterize skeletal proportions to assess the genetic root of these traits and their connections to each other.

26 Jul 2023

Unraveling the genetic code of bipolar disorder

Researchers investigate the genetic associations and heritability between categorical and dimensional bipolar disorder models.

14 Jul 2023

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Researchers performed a protein diffusion network analysis using tissue-specific GRNs to identify predispositions to COVID-19.

21 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Study endeavors to strengthen genomic diagnosis of rare pediatric diseases in the United Kingdom and Ireland

Researchers performed a large-scale sequencing study using data gathered over a decade from a previous study.

14 Apr 2023

The international spread of drug-resistant Shigella sonnei

Researchers examined the international dissemination of the outbreak of extensively drug-resistant Shigella sonnei.

12 Apr 2023

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for toxigenic lineage M1UK

Study explores the emerging invasive group A Streptococcus M1uk lineage,

7 Apr 2023

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Researchers evaluated the effects of poor diet quality and lifestyle behaviors on modifying the genomic susceptibility to impulsivity.

30 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Candida auris infection without epidemiologic links to a prior outbreak

The Centers for Disease Control and Prevention (CDC) has classified Candida auris (C. auris) as an urgent public threat due to its role in elevating mortality, its ability to persist in hospital environments, and the high possibility of developing pan-drug resistance.

23 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting.

15 Mar 2023

Study suggests a link between the protein-coding gene TREM2 and obesity in females

A recent Scientific Reports study has investigated the link between TREM2 expression and human obesity, based on two large public datasets, namely, the UK Biobank (UKB) and the Genotype-Tissue Expression (GTEx) project.

11 Jan 2023

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

SARS-CoV-2 detected in white-tailed deer in Canada

Researchers investigated the detection of SARS-CoV-2 in white-tailed deer.

14 Nov 2022

First report of natural recombination of monkeypox virus genome

Researchers analyzed monkeypox virus sequences during the current 2022 outbreak to investigate whether MPXV is adapting for improved survival and viral transmission among humans.

27 Oct 2022

AI-guided tools pinpoint immune cell driver and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus - the tube connecting the throat to the stomach.

22 Sep 2022

New case study provides comprehensive characterization and follow-up of monkeypox infection

In a recent monkeypox case in Sweden, scientists focused on clinical symptoms, viral kinetics, and microbial diagnostics.

31 Aug 2022

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

Verogen, Inc. and Gene by Gene today announced a partnership to accelerate the adoption of forensic investigative genetic genealogy.

From Verogen, Inc. 16 Aug 2022

Genetic variations in serotonin receptor causes different response to psychedelic drugs

Cluster headaches, anxiety and depression can be debilitating for people living with these conditions. Psychedelic drugs have shown benefits as treatments for these conditions in clinical studies, but not for everyone.

27 Jul 2022