Embryonic Development News and Research

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Embryonic development or embryogenesis is the process by which the embryo is formed and develops. It starts with the fertilization of the ovum, egg, which, after fertilization, is then called a zygote. The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo.

'Dark matter' in human genome may play role in cancer biology and cell death

The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.

1 Aug 2013

Findings open new perspectives for research on proteins that control metastasis

In experiments on zebrafish, Freiburg researchers have demonstrated that the same proteins that lead to the formation of metastases in humans also cause the cells to migrate during embryonic development.

24 Jul 2013

New research project has potential to treat human deafness and loss of balance

The sounds of success are ringing at Kansas State University through a research project that has potential to treat human deafness and loss of balance.

20 Jul 2013

Pair of studies sheds light on cancer cell signaling

A pair of studies by a team of University of Notre Dame researchers led by Crislyn D'Souza-Schorey, professor of biological sciences, sheds light on a biological process which is activated across a vast range of malignancies.

16 Jul 2013

Research opens door to better understanding of inner-ear development process, potential treatments

Indiana University scientists have transformed mouse embryonic stem cells into key structures of the inner ear. The discovery provides new insights into the sensory organ's developmental process and sets the stage for laboratory models of disease, drug discovery and potential treatments for hearing loss and balance disorders.

12 Jul 2013

Study confirms role of MAPK mutations in pilocytic astrocytomas

Brain cancer is the primary cause of cancer mortality in children. Even in cases when the cancer is cured, young patients suffer from the stress of a treatment that can be harmful to the developing brain. In a search for new target structures that would create more gentle treatments, cancer researchers are systematically analyzing all alterations in the genetic material of these tumors.

10 Jul 2013

Scientists identify molecular signals that spur the formation of arteries

The ability to form blood vessels is one of evolution's crowning achievements, and something that separates vertebrates (animals with a backbone) from the rest of the animal kingdom.

4 Jul 2013

Study: IVF treatment linked with increased risk of mental retardation

In a study that included more than 2.5 million children born in Sweden, compared with spontaneous conception, any in vitro fertilization (IVF) treatment was not associated with autistic disorder but was associated with a small but statistically significantly increased risk of mental retardation, according to a study in the July 3 issue of JAMA. The authors note that the prevalence of these disorders was low, and the increase in absolute risk associated with IVF was small.

3 Jul 2013

New study explains how the brain maintains zinc balance during embryonic development

A new study helps explain how parts of the brain maintain their delicate balance of zinc, an element required in minute but crucial doses, particularly during embryonic development.

27 Jun 2013

FDA grants fast track designation to Genervon Biopharmaceuticals for ALS drug GM604

In a huge victory for ALS sufferers, FDA granted Genervon Biopharmaceuticals a fast track designation for its first in class highly effective multi-target master regulator biotechnology drug GM604 for ALS. FDA said it met the necessary criteria.

27 Jun 2013

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism, and bipolar disorder, according to new research by UC San Francisco scientists.

25 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

Early exposure to BPA increases risk for prostate cancer in human prostate tissue

Early exposure to BPA (bisphenol A) - an additive commonly found in plastic water bottles and soup can liners - causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.

18 Jun 2013

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Scientists at the Danish Stem Cell Center, DanStem, at the University of Copenhagen have discovered that they can make embryonic stem cells regress to a stage of development where they are able to make placenta cells as well as the other fetal cells.

7 Jun 2013

Innovative X-ray method advances new treatments for genetic diseases

An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.

18 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Research on total anomalous pulmonary venous connection

Total anomalous pulmonary venous connection, one type of "blue baby" syndrome, is a potentially deadly congenital disorder that occurs when pulmonary veins don't connect normally to the left atrium of the heart.

13 May 2013

Researchers find a way the body can remove injured axons

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that transmit signals to other parts of the body, allowing movement, sight and sense of touch, among other vital functions.

10 May 2013

Research findings have important implications for developmental and cancer biology

Researchers from Huntsman Cancer Institute at the University of Utah have discovered that while the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different state and must be reprogrammed to match.

10 May 2013

Researchers reveal how genes are turned on and off during early human development

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human development.

10 May 2013

Embryonic Development News and Research

Further Reading

'Dark matter' in human genome may play role in cancer biology and cell death

Findings open new perspectives for research on proteins that control metastasis

New research project has potential to treat human deafness and loss of balance

Pair of studies sheds light on cancer cell signaling

Research opens door to better understanding of inner-ear development process, potential treatments

Study confirms role of MAPK mutations in pilocytic astrocytomas

Scientists identify molecular signals that spur the formation of arteries

Study: IVF treatment linked with increased risk of mental retardation

New study explains how the brain maintains zinc balance during embryonic development

FDA grants fast track designation to Genervon Biopharmaceuticals for ALS drug GM604

UCSF scientists explore how Dact1 mutations contribute to psychiatric disorders

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Early exposure to BPA increases risk for prostate cancer in human prostate tissue

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Innovative X-ray method advances new treatments for genetic diseases

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Research on total anomalous pulmonary venous connection

Researchers find a way the body can remove injured axons

Research findings have important implications for developmental and cancer biology

Researchers reveal how genes are turned on and off during early human development

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