RNA Sequencing News and Research

RSS

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

In 2012, University of Alabama at Birmingham researcher Anath Shalev, M.D., reported that a decades-old blood pressure medication called verapamil completely reversed diabetes in animal models.

25 Aug 2023

Genetics and environment influence immune responses to SARS-CoV-2

During the COVID-19 pandemic, the clinical spectrum observed among people infected with SARS-CoV-2 ranged from asymptomatic carriage to death.

24 Aug 2023

New method could make single-cell RNA sequencing more accessible to patients

To improve therapies for cancer and other diseases, researchers strive to identify tissue-specific therapeutic targets and diagnostic biomarkers in every patient.

22 Aug 2023

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

A study finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis.

22 Aug 2023

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

The impacts of physical activity on the neuronal formation and prevent age-related cognitive decay.

22 Aug 2023

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Global team of experts outlines roadmap for human skin cell atlas

As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking.

21 Aug 2023

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Researchers used visual flickering sensory stimulation to reveal the underlying mechanisms governing microglial morphology and cytokine expression in mice.

16 Aug 2023

Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

A research team led by Prof. ZHU Shu from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) illustrated the role of Gasdermin D (GSDMD) protein in immunity tolerance to food in the small intestine.

11 Aug 2023

A drug for heart conditions improves efficacy of melanoma therapies

A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d'Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) shows that the administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease.

10 Aug 2023

Study provides clues to how harmful T cells cause heart disease

Scientists can finally hunt down a harmful kind of human T cell, thanks to new research led by scientists at La Jolla Institute for Immunology (LJI) and the Medical College of Georgia (MCG) at Augusta University.

10 Aug 2023

Lizards' ability to regenerate cartilage could lead to new treatments for osteoarthritis

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

10 Aug 2023

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions.

10 Aug 2023

Spatially-resolved macrophage phenotyping in liver disease-related research

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.

8 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Study identifies gene fusions to understand their relationship with observed pathologies in cancer patients.

8 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

The genetics of resting heart rate and its connection to cardiovascular disorders

Researchers investigated the genetics behind resting heart rate and its impact on cardiovascular disease.

7 Aug 2023

RNA Sequencing News and Research

UAB researchers show beneficial effect of verapamil for patients with Type 1 diabetes

Genetics and environment influence immune responses to SARS-CoV-2

New method could make single-cell RNA sequencing more accessible to patients

Study identifies an endogenous bile acid that alleviates non-alcoholic fatty liver disease

Platelets play a role in mediating the rejuvenating effects of exercise during physiological brain ageing

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

Global team of experts outlines roadmap for human skin cell atlas

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Stem cells used to create organoids that secrete dental enamel proteins

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

A drug for heart conditions improves efficacy of melanoma therapies

Study provides clues to how harmful T cells cause heart disease

Lizards' ability to regenerate cartilage could lead to new treatments for osteoarthritis

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Spatially-resolved macrophage phenotyping in liver disease-related research

NLRP3 inflammasome plays a role in podocyte aging

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

The genetics of resting heart rate and its connection to cardiovascular disorders

Sequencing & Genomics: Elevating Science and Healthcare eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer