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Researchers discover key aspect in pathogenesis of multiple sclerosis

A team of researchers the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain.

4 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Gene editing could prevent the evolution of drug-resistant bacteria

Researchers have found a way of preventing the emergence of antibiotic-resistant bacteria, a promising new discovery in the fight against deadly superbugs.

3 Sep 2018

New project aims to combat drug-resistant bacteria in hospitals

Antibiotic resistance is a big global public health problem. Of particular concern are multidrug-resistant Gram-negative bacteria, which are among the leading causes of serious, debilitating and life threatening healthcare-associated infections.

3 Sep 2018

UCLA biologists find 8,000 new antibiotic combinations to be effective

Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns.

3 Sep 2018

Genetic disruption strategy effectively stymies evolution of drug-resistant pathogens

A genetic disruption strategy developed by University of Colorado Boulder researchers effectively stymies the evolution of antibiotic-resistant bacteria such as E. coli, giving scientists a crucial leg up in the ongoing battle against deadly superbugs.

3 Sep 2018

A genetic signal-transmission system for the gut microbiome

More than 1,000 species of bacteria have been identified in the human gut, and understanding this incredibly diverse "microbiome" that can greatly impact health and disease is a hot topic in scientific research.

31 Aug 2018

Scientists shed light on how dangerous inflammations are caused in the brain

The so-called CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of “sensor” with which neurons measure and control the activity of certain immune cells in the brain.

31 Aug 2018

Researchers report challenges in reducing tetanus mortality

The overall mortality in patients suffering non-neonatal tetanus is high. Efforts to reduce mortality in one sub-Saharan African intensive care unit by implementing a standard tetanus protocol did little to change mortality rates, although they shifted causes of deaths, researchers have now reported in PLOS Neglected Tropical Diseases.

31 Aug 2018

New assay using cellphone cameras developed for testing mosquitos, Wolbachia

Wolbachia bacteria are widely studied for possible properties to block transmission of viruses like chikungunya, dengue and zika.

31 Aug 2018

UQ researchers discover new immune defense pathway deployed against bacteria

A new understanding of one of the body’s immune defense mechanisms could lead to the development of novel therapeutic targets for conditions such as cancer and autoimmune diseases, a University of Queensland study has revealed.

31 Aug 2018

Study provides insights into how harmful white blood cells form during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues.

31 Aug 2018

Modified Nurr1 protein may pave way for new Parkinson's therapy

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson's disease.

31 Aug 2018

Newborns require special diagnosis and treatment considerations for C. difficile infection

Newborns require special diagnosis and treatment considerations for an infectious diarrhea known as Clostridioides difficile infection, according to a new evidence-based white paper published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

31 Aug 2018

Gut bacteria helps develop more beige fat with restricted calorie intake

Mice with a lower calorie intake live longer and are both healthier and leaner. A team of researchers funded by the SNSF may have found the reason for this positive effect: much of it is down to gut microbial communities and how they affect the immune system.

31 Aug 2018

KU Leuven study: Macrophages in the intestine can survive for a long time

Macrophages are specialized immune cells that destroy bacteria and other harmful organisms. KU Leuven scientists, Belgium, have come to the surprising conclusion that some macrophages in the intestines of mice can survive for quite some time.

30 Aug 2018

UTA scientists map function of enzymes to provide keys for developing new drugs

UTA biochemists are mapping the function of specific enzymes which may facilitate development of new drugs to fight bacterial infection, cancer and potentially neurodegenerative diseases like autism, Down syndrome, Parkinson's disease and Alzheimer's.

30 Aug 2018

Researchers provide new virulence clues through genomic study of anthrax strains

By analyzing genomic sequences from more than 400 strains of the bacterium that causes anthrax, researchers have provided the first evidence that the severity - technically known as virulence - of specific strains may be related to the number of copies of certain plasmids they carry.

30 Aug 2018

The pluses and minuses of allowing medical marijuana at school

Every school day at noon, Karina Garcia drives to her son’s South San Francisco high school to give him a dose of cannabis oil to prevent potentially life-threatening seizures.

30 Aug 2018