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New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

Scientists at NYU Langone Medical Center's Center for Cognitive Neurology have evidence that monoclonal antibodies they developed may provide the blueprint for effective treatments for Alzheimer's disease and other neurodegenerative diseases, such as Parkinson's disease.

21 Jul 2015

New approach to imaging glucose uptake activity in single living cells

Researchers at Columbia University have reported a new approach to visualize glucose uptake activity in single living cells by light microscopy with minimum disturbance. In a recent study published in Angewandte Chemie International Edition, Associate Professor of Chemistry Wei Min's team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.

20 Jul 2015

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

By analyzing the signals of individual neurons in animals undergoing behavioral tests, neuroscientists at Rice University, Baylor College of Medicine, the University of Geneva and the University of Rochester have deciphered the code the brain uses to make the most of its inherently "noisy" neuronal circuits.

17 Jul 2015

Next-generation tissue implant allows neuroscientists to wirelessly control neurons inside the brains of mice

A study showed that scientists can wirelessly determine the path a mouse walks with a press of a button. Researchers at the Washington University School of Medicine, St. Louis, and University of Illinois, Urbana-Champaign, created a remote controlled, next-generation tissue implant that allows neuroscientists to inject drugs and shine lights on neurons deep inside the brains of mice.

17 Jul 2015

New project aims to revolutionize application of optogenetics in neuroscience

The revolution that optogenetics technology has brought to biology -- neuroscience in particular -- could be transformed all over again if a new project getting underway at Brown University and Central Michigan University is successful.

17 Jul 2015

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Results of a new study reported this week by David Moorman of the University of Massachusetts Amherst and Gary Aston-Jones of Rutgers University suggest that adjusting behavior based on previous events involves an unexpected mix of neurons working together in the brain's prefrontal cortex.

17 Jul 2015

Discovery brings hope for people suffering from Parkinson's disease

Scientists from Singapore's Nanyang Technological University and McLean Hospital and Harvard Medical School in the United States have found that existing anti-malaria drugs could be a potential treatment for Parkinson's disease.

16 Jul 2015

New research offers potential for early intervention to prevent neurodegenerative diseases

New research led by investigators at Beth Israel Deaconess Medical Center provides the first direct evidence linking traumatic brain injury to Alzheimer's disease and chronic traumatic encephalopathy (CTE) -- and offers the potential for early intervention to prevent the development of these debilitating neurodegenerative diseases.

16 Jul 2015

TSRI scientists reveal how mutations in specific autism risk gene alter pattern of early brain development

As early as 1943, when autism was first described by psychiatrist Leo Kanner, reports were made that some, but not all, children with autism spectrum disorder have relatively enlarged heads. But even today, more than half a century later, the exact cause of this early abnormal growth of the head and brain has remained unclear.

16 Jul 2015

U of T researchers discover new details about key gene involved in ALS

A University of Toronto research team has discovered new details about a key gene involved in ALS, perhaps humanity's most puzzling, intractable disease.

16 Jul 2015

Scientists propose new spinal cord stimulation strategy to activate motor neurons

Patients, doctors and researchers look with great expectations to epidural electrostimulation, a medical technique that could alleviate the condition of subjects affected by paralysis due to spinal cord injury. Although still relatively rudimentary, the technique is constantly being improved thanks to research.

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

Retrosplenial cortex serves as 'conjunction junction' for brain's navigation function

Ever wake at night needing a drink of water and then find your way to the kitchen in the dark without stubbing your toe?

10 Jul 2015

MGH investigators report that medication could augment benefits of bariatric surgery

New findings about the mechanisms involved - or not involved - in the effects of the most common form of bariatric surgery suggest that combining surgery with a specific type of medication could augment the benefits of the procedure. In a report that has been published online in the journal Endocrinology, Massachusetts General Hospital investigators report that the effects of Roux-en-Y gastric bypass (RYGB) do not utilize neurologic pathways controlled by the serotonin 2C receptor.

9 Jul 2015

International research team identifies new gene associated with 4H leukodystrophy

Leukodystrophies are deadly neurodegenerative diseases that affect one in 7,000 children and remain incurable. These genetic diseases attack myelin or the "insulating rubber sheath" surrounding neurons, which leads to deteriorating health for affected children.

9 Jul 2015

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer's disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.

8 Jul 2015

Decreased connectivity between network-specific brain regions linked to cognitive deficit in MS

An estimated 2.3 million individuals are living with multiple sclerosis (MS) worldwide. Approximately half of all individuals with MS experience changes in cognition such as impaired concentration, attention, memory, and judgment. The underlying brain basis for these deleterious effects has been largely elusive.

8 Jul 2015

New findings can help scientists generate tailor-made proteins optimized for use in optogenetics

Optogenetics techniques, which allow scientists to map and control nerve cells using light stimulation, are being used to study neural circuits in the brain with unprecedented precision. This revolutionary technology relies on light-sensitive proteins such as channelrhodopsins, and researchers at UC Santa Cruz have now determined the molecular mechanism involved in the light-induced activation of one of these proteins.

7 Jul 2015

MIT researchers reveal key brainwave changes among patients receiving nitrous oxide

Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a study published this week in Clinical Neurophysiology, MIT researchers reveal some key brainwave changes among patients receiving the drug.

7 Jul 2015

Neurons News and Research

New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

New approach to imaging glucose uptake activity in single living cells

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

Next-generation tissue implant allows neuroscientists to wirelessly control neurons inside the brains of mice

New project aims to revolutionize application of optogenetics in neuroscience

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Discovery brings hope for people suffering from Parkinson's disease

New research offers potential for early intervention to prevent neurodegenerative diseases

TSRI scientists reveal how mutations in specific autism risk gene alter pattern of early brain development

U of T researchers discover new details about key gene involved in ALS

Scientists propose new spinal cord stimulation strategy to activate motor neurons

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

Retrosplenial cortex serves as 'conjunction junction' for brain's navigation function

MGH investigators report that medication could augment benefits of bariatric surgery

International research team identifies new gene associated with 4H leukodystrophy

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Decreased connectivity between network-specific brain regions linked to cognitive deficit in MS

New findings can help scientists generate tailor-made proteins optimized for use in optogenetics

MIT researchers reveal key brainwave changes among patients receiving nitrous oxide

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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