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Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

Dopamine, a powerful brain chemical and neurotransmitter, is a key regulator of many important functions such as attention, experiencing pleasure and reward, and coordinating movement.

12 Aug 2024

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

In a groundbreaking study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several neurodegenerative and psychiatric disorders, including multiple sclerosis, Alzheimer's disease, and schizophrenia.

12 Aug 2024

New study links brain cell structures to memory loss in aging and dementia

Researchers assessed whether dendritic spine head diameter in the temporal cortex is a better predictor of episodic memory performance in older adults than synapse quantity, accounting for β amyloid plaques, neurofibrillary tangles, and sex.

12 Aug 2024

Can odors help fight infection? Nematode research suggests so

Researchers from the University of California, Berkeley, used the nematode model Caenorhabditis elegans to determine whether the olfactory nervous system could non-autonomously control the mitochondrial unfolded protein response in response to cellular stress.

12 Aug 2024

Brain circuits connecting stress to gut bacteria reveal new pathways for immune regulation

Researchers have discovered a brain-gut circuit that links stress to changes in gut bacteria, revealing that emotional states can directly influence immune function through the duodenal glands.

11 Aug 2024

Prenatal BPA exposure tied to autism risk in boys

Study reveals that prenatal exposure to BPA disrupts aromatase activity in male brains, potentially leading to autism-like symptoms. Treatment with 10-HDA shows promise in reversing these effects.

11 Aug 2024

ATP regulation in ClC-3 exchangers linked to neurodegenerative diseases, study reveals

Researchers structurally analyzed adenine nucleotide control and neurodegenerative diseases in ClC-3 exchangers.

11 Aug 2024

Study reveals how NPAS4 regulates drug-context associations and impacts relapse

Most people wouldn't think twice after seeing sugar spilled on a counter. But for someone with a history of cocaine use, this visual cue could trigger powerful associations with their past drug use and a compulsive urge to seek the drug.

9 Aug 2024

Mechanisms of tissue shape transformation revealed through fruit fly wing development

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development.

9 Aug 2024

New insights into retrotransposon-derived DNA zip codes in myeloma cells

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization."

9 Aug 2024

EZH2's role in cancer progression and therapy explored

Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of the Polycomb-repressive complex 2 (PRC2), which plays a crucial role in transcriptional repression through the methylation of histone H3 on lysine 27 (H3K27me3).

9 Aug 2024

Study shows how Western classical music elicits positive effects on the brain

Whether Bach, Beethoven, or Mozart, it's widely recognized that classical music can affect a person's mood.

9 Aug 2024

High-throughput sperm selection system shows promising results for low motility cases

An advanced sperm selection system for men experiencing sperm with low motility has been announced by scientists at City University of Hong Kong (CityUHK).

9 Aug 2024

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

Most tumors release various signaling molecules to support their incessant growth, invasion, and metastasis.

9 Aug 2024

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health.

9 Aug 2024

Machine learning revolutionizes gene delivery

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.

9 Aug 2024

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions.

9 Aug 2024

Inflammation during pregnancy impacts child neurodevelopment

When a person experiences an injury or infection, the body's immune system responds with inflammation to start the healing process. However, inflammation can occur in much less helpful circumstances – for example, when a person experiences psychological stress or consistently eats a poor diet high in sugars, fats, and processed foods.

9 Aug 2024

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

Korean researchers accelerate race for respiratory disease cures

The COVID-19 pandemic has profoundly impacted our lives, claiming nearly 7.1 million lives globally. Scientists and medical professionals have been working tirelessly to understand the virus, its transmission pathways, and effective treatments. The urgency of developing vaccines and treatments has never been greater, prompting calls for Korea to expedite its drug development efforts to match those of developed countries. Recently, a team of Korean researchers has made a breakthrough that will greatly enhance the efficiency of respiratory disease research, garnering attention.

9 Aug 2024

Cell News and Research

Researchers identify key genetic players in dopamine signaling using transparent worms With The Help Of A Tin...

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

New study links brain cell structures to memory loss in aging and dementia

Can odors help fight infection? Nematode research suggests so

Brain circuits connecting stress to gut bacteria reveal new pathways for immune regulation

Prenatal BPA exposure tied to autism risk in boys

ATP regulation in ClC-3 exchangers linked to neurodegenerative diseases, study reveals

Study reveals how NPAS4 regulates drug-context associations and impacts relapse

Mechanisms of tissue shape transformation revealed through fruit fly wing development

New insights into retrotransposon-derived DNA zip codes in myeloma cells

EZH2's role in cancer progression and therapy explored

Study shows how Western classical music elicits positive effects on the brain

High-throughput sperm selection system shows promising results for low motility cases

Review explores potential for improved use of anti-angiogenic agents in cancer therapy

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Machine learning revolutionizes gene delivery

Breakthrough study uncovers TIP60’s role in DNA access and disease mechanisms

Inflammation during pregnancy impacts child neurodevelopment

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Korean researchers accelerate race for respiratory disease cures

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