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FDA moves to curb Avastin's approval for breast cancer

The Food and Drug administration on Thursday revoked its approval of Roche drug Avastin for the treatment of breast cancer. The agency's action, based on findings that did not confirm that the medicine helped patients with this disease, has drawn criticism from patients and politicians.

20 Dec 2010

Alnylam Pharmaceuticals progress in delivery and translation of RNAi therapeutics

Alnylam Pharmaceuticals, a leading RNAi therapeutics company, presented new data at the 2010 International Chemical Congress of Pacific Basin Societies, being held in Honolulu, Hawaii, December 15-20.

17 Dec 2010

Reuters rates hospitals' cardiovascular program

Loyola University Hospital's mortality rate from heart-bypass surgery is 74 percent lower than the mortality rate at peer hospitals, according to Thomson Reuters Cardiovascular Benchmarks Report.

17 Dec 2010

Enzon in collaboration with NCI initiates EZN-2968, EZN-2208 Phase I studies for arresting tumor growth

Enzon Pharmaceuticals, today announced the initiation of Phase I clinical studies, in collaboration with the National Cancer Institute, for two of the Company's novel oncology product candidates, EZN-2968 and EZN-2208 (PEG-SN38).

16 Dec 2010

New hypothesis emphasizes the value of anti-inflammatory approaches to prevent Alzheimer's disease

Karl Herrup thinks that the national research effort to understand Alzheimer-s disease has gone about as far as it can go with its current theories.

15 Dec 2010

NCI initiates crolibulin/cisplatin combination Phase II trial in anaplastic thyroid cancer

EpiCept Corporation today announced that the National Cancer Institute (NCI) has initiated a Phase II trial with crolibulinTM (EPC2407). The trial will assess the drug's efficacy and safety in combination with cisplatin in patients with anaplastic thyroid cancer (ATC). CrolibulinTM is a vascular disruption and apoptosis inducing agent that has demonstrated potent anti-tumor activity in both preclinical and early clinical studies.

15 Dec 2010

Angiogenesis inhibition is a validated strategy for cancer therapy

Scientists at the Dana-Farber Cancer Institute may have uncovered a mechanism for blocking tumor angiogenesis that involves the patient's immune system, according to findings published in Cancer Research, a journal of the American Association for Cancer Research.

15 Dec 2010

Y-90 microspheres pack a therapeutic punch against late-stage liver cancer

The latest weapon against inoperable liver cancer is so tiny that it takes millions of them per treatment, but according to interventional radiologists at the Indiana University School of Medicine, those microscopic spheres really pack a therapeutic punch.

15 Dec 2010

Study links large waistline to increased risk of heart problems and type 2 diabetes

Researchers at Eastern Virginia Medical School’s Strelitz Diabetes Center and the school’s department of physiological sciences have published research showing a strong link between a large waistline and increased risk of Type 2 diabetes and cardiovascular disease.

14 Dec 2010

Gore releases statement in response to safety of GORE HELEX Septal Occluder for PFO closure in cryptogenic stroke patients

W. L. Gore & Associates (Gore) today released the following statement from the Gore REDUCE Clinical Study Principal Investigators on behalf of the Gore REDUCE Clinical Study Steering Committee in response to the recent CLOSURE I results presentation.

14 Dec 2010

Study finds carotid artery stenting has higher risk of stroke and death than carotid endarterectomy

To meet reimbursement criteria, candidates for carotid artery stenting (CAS) must either be high-risk surgical patients or be enrolled in a critical trial.

14 Dec 2010

Researchers examine outcomes related to antiplatelet therapy in patients undergoing CEA

Despite the common clinical practice among surgeons to discontinue their patients' anti-platelet therapy prior to surgery, a recent study of patients undergoing carotid endarterectomy (CEA) indicated that this practice may be unnecessary.

13 Dec 2010

Pfizer withdraws Thelin for treatment of PAH, discontinues global clinical studies

Pfizer Inc. announced today that, in the interest of patient safety, it is voluntarily withdrawing Thelin® (sitaxentan) for the treatment of pulmonary arterial hypertension (PAH) in regions where it is approved (the European Union, Canada and Australia). In addition, Pfizer is discontinuing clinical studies of Thelin worldwide.

10 Dec 2010

Blocking growth of blood vessels with antibodies could improve treatment of cancerous tumors

A novel strategy of blocking the growth of blood vessels with antibodies should result in improved treatment of cancerous tumors.

10 Dec 2010

Researchers target MIC-1 protein to halt growth of melanoma tumors

Halting the growth of melanoma tumors by targeting the MIC-1 protein that promotes blood vessel development in tumors may lead to better treatment of this invasive and deadly cancer, according to Penn State College of Medicine researchers in The Foreman Foundation Research Laboratory.

10 Dec 2010

Acorda initiates enrollment in GGF2 Phase 1 clinical trial in patients with heart failure

Acorda Therapeutics, Inc. today announced that the first patient has been enrolled in the first clinical trial of Glial Growth Factor 2 (GGF2). Acorda is collaborating with the Vanderbilt University Heart and Vascular Institute to conduct this Phase 1 single-dose trial in patients with heart failure.

9 Dec 2010

LUMEDX implements CardioInventory software at Iowa Health Systems' affiliate hospitals

LUMEDX Corporation, a leading provider of vendor-neutral, integrated cardiovascular imaging and information systems (CVIS), announced the successful implementation of CardioInventory at nine Iowa Health Systems (IHS) affiliate hospitals. The final go-live at St. Luke's Medical Center in Cedar Rapids represents an important milestone in the ongoing installation of a centralized, enterprise-wide LUMEDX cardiovascular image- and data-management system for Iowa Health System.

9 Dec 2010

Palomar announces global availability of MaxG Optimized Pulsed Light

Palomar Medical Technologies, Inc., a leading researcher and developer of light-based systems for aesthetic treatments, is pleased to announce that the MaxG™ Optimized Pulsed Light™ (OPL) handpiece is now available worldwide for use on the company's StarLux® 500 and Artisan™ laser and pulsed light aesthetic systems.

9 Dec 2010

New report indicates that struggling economy may have reduced use of preventive care

A new report released by non-profit health care organization MN Community Measurement, indicates that the struggling economy may have reduced the use of preventive care, including breast cancer screenings and childhood immunizations, as well as the on-going care needed for chronic diseases like diabetes and vascular disease.

9 Dec 2010

Researchers discover central switch that regulates movement of cancer cells

Researchers at the University of Georgia have discovered a central switch that controls whether cells move or remain stationary. The misregulation of this switch may play a role in the increased movement of tumor cells and in the aggressiveness of tumors themselves.

9 Dec 2010

Vascular News and Research

FDA moves to curb Avastin's approval for breast cancer

Alnylam Pharmaceuticals progress in delivery and translation of RNAi therapeutics

Reuters rates hospitals' cardiovascular program

Enzon in collaboration with NCI initiates EZN-2968, EZN-2208 Phase I studies for arresting tumor growth

New hypothesis emphasizes the value of anti-inflammatory approaches to prevent Alzheimer's disease

NCI initiates crolibulin/cisplatin combination Phase II trial in anaplastic thyroid cancer

Angiogenesis inhibition is a validated strategy for cancer therapy

Y-90 microspheres pack a therapeutic punch against late-stage liver cancer

Study links large waistline to increased risk of heart problems and type 2 diabetes

Gore releases statement in response to safety of GORE HELEX Septal Occluder for PFO closure in cryptogenic stroke patients

Study finds carotid artery stenting has higher risk of stroke and death than carotid endarterectomy

Researchers examine outcomes related to antiplatelet therapy in patients undergoing CEA

Pfizer withdraws Thelin for treatment of PAH, discontinues global clinical studies

Blocking growth of blood vessels with antibodies could improve treatment of cancerous tumors

Researchers target MIC-1 protein to halt growth of melanoma tumors

Acorda initiates enrollment in GGF2 Phase 1 clinical trial in patients with heart failure

LUMEDX implements CardioInventory software at Iowa Health Systems' affiliate hospitals

Palomar announces global availability of MaxG Optimized Pulsed Light

New report indicates that struggling economy may have reduced use of preventive care

Researchers discover central switch that regulates movement of cancer cells

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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