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Breathwork may mimic psychedelic effects through brain changes

Breathwork while listening to music may induce a blissful state in practitioners, accompanied by changes in blood flow to emotion-processing brain regions, according to a study published August 27, 2025, in the open-access journal PLOS One by Amy Amla Kartar from the Colasanti Lab in the Department of Clinical Neuroscience at Brighton and Sussex Medical School, U.K., and colleagues.

28 Aug 2025

No Surprises Act significantly reduces out of pocket healthcare costs

Investigators at Mass General Brigham and the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center have uncovered how patients' healthcare spending has changed following the implementation of the No Surprises Act in 2022, a bipartisan law prohibiting unexpected or "surprise" bills after patients receive out-of-network medical care.

28 Aug 2025

Polysubstance-involved opioid overdoses found to be prevalent among youth

Most research suggests that opioid overdoses involving multiple substances in the United States typically occur among people ages 25-54.

26 Aug 2025

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

Researchers found that acoustic emission dose-an acoustic signal from microbubbles-could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma.

25 Aug 2025

History of traumatic brain injury tied to greater chance of malignant brain tumors

New research led by investigators at Mass General Brigham suggests a link between a history of traumatic brain injury (TBI) and risk of developing a malignant brain tumor.

25 Aug 2025

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk.

25 Aug 2025

Working-age adults with disabilities face much higher rates of loneliness

Working-age adults with disabilities experience far higher rates of loneliness than those without, according to a new study from researchers at the Brown University School of Public Health and the Warren Alpert Medical School.

22 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

Aston Medical School secures NIHR funding for 12 academic clinical fellows

Aston Medical School has successfully bid for funding from the National Institute for Health and Care Research (NIHR) for 12 Academic Clinical Fellows.

22 Aug 2025

How generative AI scribes are reducing physician burnout

A new study led by Mass General Brigham researchers reveals that ambient documentation technologies – generative artificial intelligence scribes that record patient visits and draft clinical notes for physician review before incorporating them into electronic health records – led to significant reductions in physician burnout.

22 Aug 2025

Computational approach provides insight into neural progenitor cells and their role in brain disorders

For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

21 Aug 2025

'Global Guardians' camp fosters young minds in pandemic preparedness

The Global Virus Network (GVN), in partnership with the University of South Florida (USF) Youth Experiences and Hillsborough County Public Schools STEM Department, recently concluded its inaugural "Global Guardians: Youth for Pandemic Preparedness" summer camp, an immersive, hands-on experience that brought together some of Tampa's brightest high school students with internationally renowned virologists, public health experts, and scientists.

21 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

Seven blood metabolites associated with excessive daytime sleepiness

Mass General Brigham researchers identified seven molecules in the blood linked to excessive daytime sleepiness, including factors related to diet and hormones.

20 Aug 2025

Physician retention in New York reaches highest level in nearly a decade

The percentage of physicians who go on to practice in New York State after completing their residency training continues to climb.

19 Aug 2025

FAST walk shows promise in improving gait for chronic stroke patients

Stroke remains one of the leading causes of long-term disability worldwide, affecting millions each year.

19 Aug 2025

Aggressive blood pressure management offers greater health benefits

Research led by investigators at Mass General Brigham suggests that the health benefits of more aggressive blood pressure control outweigh concerns about overtreating people with high blood pressure readings. Results of the simulation study are published in Annals of Internal Medicine.

19 Aug 2025

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

The American Geriatrics Society (AGS) has released a landmark update to its list of alternatives to medications listed in the 2023 AGS Beers Criteria - the most widely adopted guidelines to help clinicians identify potentially inappropriate medications for older adults.

18 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Medical School News and Research

Breathwork may mimic psychedelic effects through brain changes

No Surprises Act significantly reduces out of pocket healthcare costs

Polysubstance-involved opioid overdoses found to be prevalent among youth

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

History of traumatic brain injury tied to greater chance of malignant brain tumors

Mediterranean-style diet may reduce dementia risk in individuals with high genetic risk

Working-age adults with disabilities face much higher rates of loneliness

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

Aston Medical School secures NIHR funding for 12 academic clinical fellows

How generative AI scribes are reducing physician burnout

Computational approach provides insight into neural progenitor cells and their role in brain disorders

'Global Guardians' camp fosters young minds in pandemic preparedness

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

Rethinking chronic disease management in older adults

Seven blood metabolites associated with excessive daytime sleepiness

Physician retention in New York reaches highest level in nearly a decade

FAST walk shows promise in improving gait for chronic stroke patients

Aggressive blood pressure management offers greater health benefits

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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