Radiotherapy News and Research

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Radiation therapy (in North America), or radiotherapy (in the UK and Australia) also called radiation oncology, and sometimes abbreviated to XRT, is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis).

Targeted therapy slows disease progression and improves survival for prostate cancer

A new PARP-inhibitor has been shown to significantly delayed cancer progression among patients with prostate cancer who had cancer cells with faulty DNA repair genes.

2 Oct 2019

Using X-ray-nanoparticle interactions for improved radiation therapy

A new study has indicated a new way to deliver locally aggressive radiation therapy in cancer, using the element gadolinium.

30 Sep 2019

Men with prostate cancer can be spared postoperative radiotherapy

Men with prostate cancer can be spared radiotherapy after surgery, according to late breaking results from a study led by The Royal Marsden NHS Foundation Trust.

27 Sep 2019

High-dose radiation effective for men whose prostate cancer has spread, trial shows

A randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the treatment to be an effective and safe option for patients who wish to delay hormone-suppression therapy.

26 Sep 2019

Adding radiation after immunotherapy increases PFS for some patients with metastatic NSCLC

Adding precisely aimed, escalated doses of radiation after patients no longer respond to immunotherapy reinvigorates the immune system in some patients with metastatic non-small-cell lung cancer, increasing progression-free survival.

26 Sep 2019

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

A secondary analysis of a recent clinical trial that changed the standard of care for men with recurring prostate cancer finds long-term hormone therapy does more harm than good for many men and calls for rethinking treatment guidelines based on a patient's post-operative prostate-specific antigen (PSA) level.

26 Sep 2019

UCLA researchers identify new drug delivery pathway to stop tumor growth

Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice.

25 Sep 2019

New genetic test could help avoid unnecessary prostate cancer surgery

Men who develop prostate cancer could avoid having unnecessary surgery or radiotherapy thanks to a new, more precise genetic test which is being trialed in Leeds.

25 Sep 2019

Whole-brain radiotherapy recommended for patients with brain metastases

Patients with brain metastases who received whole-brain radiotherapy that avoided memory-specific hippocampal neural stem cells experienced preserved cognitive function and reported fewer neurologic symptoms and better cognition over time, according to results from an NRG Oncology clinical trial presented Sept. 15, 2019 at the American Society for Radiation Oncology Annual Meeting in Chicago.

20 Sep 2019

Researchers describe how neurons establish contact with aggressive glioblastomas, promote tumor growth

In a current paper published in the journal "Nature", Heidelberg-based researchers and physicians describe how neurons in the brain establish contact with aggressive glioblastomas and thus promote tumor growth / New tumor activation mechanism provides starting points for clinical trials

20 Sep 2019

Anti-cancer protein promotes tumor resistance, shows study

Areas of solid tumors that have limited access to oxygen, a condition called hypoxia, are highly resilient against chemo and radiation therapy.

20 Sep 2019

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

What if a drug that sits in nearly everyone's medicine cabinet could help extend the lives of some cancer patients? In companion presentations at the American Society for Therapeutic Radiation Oncology Annual Meeting in Chicago, doctors from Roswell Park Comprehensive Cancer Center report new evidence that low-dose aspirin and other anti-inflammatories may improve survival in patients undergoing treatment for some head/neck and lung cancers.

19 Sep 2019

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Treating non-Hodgkin's lymphoma patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

18 Sep 2019

IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

Results of the NRG Oncology clinical trial NRG-HN002 indicated that the combination of intensity-modulated radiotherapy (IMRT) and cisplatin was able to meet acceptability criteria for progression-free survival (PFS) and swallowing-related quality of life for patients who have p16-positive, non-smoking-associated oropharyngeal cancer.

18 Sep 2019

Clinical trial finds no difference in pain response between SBRT and cEBRT for patients with spinal metastases

A Phase III, NRG Oncology clinical trial that compared radiosurgery or stereotactic body radiotherapy to the conventional radiotherapy for patients with spinal metastases indicated that there was no statistically significant difference between the treatments for pain response, adverse events, FACT-G, BPI, and EQ-5D scores.

17 Sep 2019

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

Initial results of NRG Oncology Clinical Trial RTOG 9601 in men with biochemically recurrent prostate cancer receiving salvage radiotherapy demonstrated improvement in OS from the addition of long-term hormone therapy to SRT.

17 Sep 2019

New biomarkers help predict response to treatment in common brain tumor

Many scientists have noted that there is a link between inflammation or the immune response, and patient survival. One such possible relationship is the association of blood markers and the prognosis in the brain tumor called medulloblastoma.

16 Sep 2019

Bias against unmarried cancer patients affects their treatment

Unmarried patients with cancer are less likely to get potentially life-saving surgery or radiotherapy than their married counterparts, raising the concern that medical providers may be relying on stereotypes that discount sources of social support other than a current spouse.

10 Sep 2019

ASTRO guideline provides recommendations on use of radiation therapy to treat pancreatic cancer

A new clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy to treat patients diagnosed with pancreatic cancer, including when radiation treatments are appropriate, as well as the optimal dosing, timing and fractionation for these treatments.

4 Sep 2019

Researchers demonstrate the effectiveness of new bladder cancer treatment

Researchers from the Molecular Cancer group at the Hospital del Mar Medical Research Institute and doctors from Hospital del Mar, have demonstrated the effectiveness of a drug for treating metastatic bladder cancer in patients who did not respond to the usual treatment.

27 Aug 2019

Radiotherapy News and Research

Further Reading

Targeted therapy slows disease progression and improves survival for prostate cancer

Using X-ray-nanoparticle interactions for improved radiation therapy

Men with prostate cancer can be spared postoperative radiotherapy

High-dose radiation effective for men whose prostate cancer has spread, trial shows

Adding radiation after immunotherapy increases PFS for some patients with metastatic NSCLC

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

UCLA researchers identify new drug delivery pathway to stop tumor growth

New genetic test could help avoid unnecessary prostate cancer surgery

Whole-brain radiotherapy recommended for patients with brain metastases

Researchers describe how neurons establish contact with aggressive glioblastomas, promote tumor growth

Anti-cancer protein promotes tumor resistance, shows study

Low-dose aspirin may improve survival in patients with head and neck, lung cancers

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

Clinical trial finds no difference in pain response between SBRT and cEBRT for patients with spinal metastases

Pre-SRT PSA could serve as prognostic and predictive biomarker of benefit from hormone therapy

New biomarkers help predict response to treatment in common brain tumor

Bias against unmarried cancer patients affects their treatment

ASTRO guideline provides recommendations on use of radiation therapy to treat pancreatic cancer

Researchers demonstrate the effectiveness of new bladder cancer treatment

Cancer Research - Second Edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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