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Study reveals how cell's protein quality control mechanism helps combat neurodegenerative diseases

A molecular pathway known to suppress tumors appears to also be a major player in clearing cells of damaged proteins implicated in neurodegenerative diseases such as ALS and certain types of dementia, new research in roundworms and human cells suggests.

6 Apr 2015

Researchers discover genetic factors key to POMC cells

The little voice inside your head that tells you to eat, or stop eating, isn't a little voice - it's actually a cluster of about 10,000 specialized brain cells. And now, an international team of scientists has found tiny triggers inside those cells that give rise to this "voice", and keep it speaking throughout life.

6 Apr 2015

Adolescent binge-drinking alters genes needed for normal brain maturation

Binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood.

3 Apr 2015

Peripheral inflammatory cells play role in Parkinson's disease

A small area in the midbrain known as the substantia nigra is the control center for all bodily movement. Increasing loss of dopamine-generating neurons in this part of the brain therefore leads to the main symptoms of Parkinson's disease - slowness of movement, rigidity and shaking.

3 Apr 2015

Mouse model may help understand the physiology behind complex brain disorders

Complex brain disorders, such as autism or schizophrenia, still puzzle scientists because their causes lie hidden in early events of brain development, which are still poorly understood.

3 Apr 2015

Researchers report that echoes, fluctuations in volume help in judging sound distance

Mammals are good at figuring out which direction a sound is coming from, whether it's a rabbit with a predator breathing down its neck or a baby crying for its mother. But how we judge how far away that sound is was a mystery until now. Researchers from UConn Health report in the 1 April issue of the Journal of Neuroscience that echoes and fluctuations in volume (amplitude modulation) are the cues we use to figure the distance between us and the source of a noise.

2 Apr 2015

Penn Med's BLINKER Team named one of 16 finalists in NIH 'Follow that Cell Challenge'

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Experimental Therapeutics, at the Perelman School of Medicine at the University of Pennsylvania, was named one of 16 finalists in the first phase of the Follow that Cell Challenge funded by the National Institutes of Health. The competition was run by crowdsourcing company Innocentive and 687 designated "solvers" entered initially.

2 Apr 2015

Research breakthrough could help develop tools to repair damaged nerve cells

A team of researchers at the IRCM led by Frédéric Charron, PhD, in collaboration with bioengineers at McGill University, uncovered a new kind of synergy in the development of the nervous system, which explains an important mechanism required for neural circuits to form properly.

1 Apr 2015

Understanding how neurons work

Before scientists can unlock the secrets of the human brain, they must fully understand neurons—the cells of our brain, spinal cord and overall nervous system. Thousands of detailed neuron images, from different organisms, currently sit in individual data collections across the globe, comprising several petabytes of data altogether.

1 Apr 2015

Patient's own skin cells may hold key to new treatments for neurological diseases

A patient's very own skin cells may hold the key to new treatments and even cures for devastating neurological diseases. A generous $1 million donation from Mr. J. Sebastian van Berkom, and critical partnerships with Brain Canada, Laval University, Marigold Foundation and the FRQS-Réseau Parkinson Quebec are driving an innovative, iPSC (induced pluripotent stem cell) research platform that will transform research into Parkinson's and other neurological diseases.

31 Mar 2015

Northwestern Medicine opens multidisciplinary treatment center for patients battling Huntington's disease

Northwestern Medicine recently launched a multidisciplinary center dedicated to the comprehensive treatment of patients battling Huntington's disease. The new center will focus on both patient care and research of the inherited disease that causes the progressive breakdown of nerve cells in the brain.

31 Mar 2015

Allen Institute for Brain Science leads international effort to advance analysis of single neurons

The Allen Institute for Brain Science is spearheading a landmark international effort to define and advance the state-of-the-art digital reconstruction and analysis of single neurons. The project launching today, called BigNeuron, aims to create reliable high-throughput and quantitative 3D reconstructions of the thousands of branches that make up individual neurons: a crucial step to ultimately understanding how the brain encodes information.

31 Mar 2015

Study finds link between neurodegenerative disorders and inflammation

Researchers from McMaster University and the Icahn School of Medicine at Mount Sinai, New York have discovered that a protein associated with neurodegenerative diseases like ALS also plays an important role in the body's natural antiviral response.

30 Mar 2015

Neuroscientists discover key building block for learning and memory formation

Researchers have been fascinated for a long time by learning and memory formation, and many questions are still open. Bochum-based neuroscientists Prof Dr Denise Manahan-Vaughan and Dr Hardy Hagena have discovered a key building block for this complex process.

30 Mar 2015

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

FUJIFILM Holdings Corporation (President: Shigehiro Nakajima) and Cellular Dynamics International, Inc. (CEO: Robert J. Palay), a leading developer and manufacturer of fully functioning human cells in industrial quantities to precise specifications, today announced that the two companies have entered into a definitive agreement whereby Fujifilm will acquire CDI via an all-cash tender offer to be followed by a second step merger.

30 Mar 2015

One in five college students experiences exploding head syndrome

Washington State University researchers have found that an unexpectedly high percentage of young people experience "exploding head syndrome," a psychological phenomenon in which they are awakened by abrupt loud noises, even the sensation of an explosion in their head.

30 Mar 2015

Rice University study reveals carbon nanotube fibers can provide two-way connection with neurons

Carbon nanotube fibers invented at Rice University may provide the best way to communicate directly with the brain.

26 Mar 2015

UCLA-led team validates first standardized protocol for tracking early signs of Alzheimer's disease

After six years of painstaking research, a UCLA-led team has validated the first standardized protocol for measuring one of the earliest signs of Alzheimer's disease -- the atrophy of the part of the brain known as the hippocampus.

26 Mar 2015

Brain-somatic-activating mutations in MTOR cause focal cortical dysplasia type II

Epilepsy is a brain disorder that afflicts more than 50 million people worldwide. Many epilepsy patients can control their symptoms through medication, but about 30% suffer from intractable epilepsy and are unable to manage the disease with drugs. Intractable epilepsy causes multiple seizures, permanent mental, physical, and developmental disabilities, and even death.

25 Mar 2015

Mexican researcher close to finding a cure for Parkinson's disease

Parkinson's disease, which took world fame after being diagnosed in various personalities such as actor Michael J. Fox, the heavyweight champion Muhammad Ali and the painter Salvador Dalí, could be very close to a cure, thanks to a Mexican researcher which managed to eliminate its neurological effects with an immunosuppressant.

25 Mar 2015

Neurons News and Research

Study reveals how cell's protein quality control mechanism helps combat neurodegenerative diseases

Researchers discover genetic factors key to POMC cells

Adolescent binge-drinking alters genes needed for normal brain maturation

Peripheral inflammatory cells play role in Parkinson's disease

Mouse model may help understand the physiology behind complex brain disorders

Researchers report that echoes, fluctuations in volume help in judging sound distance

Penn Med's BLINKER Team named one of 16 finalists in NIH 'Follow that Cell Challenge'

Research breakthrough could help develop tools to repair damaged nerve cells

Understanding how neurons work

Patient's own skin cells may hold key to new treatments for neurological diseases

Northwestern Medicine opens multidisciplinary treatment center for patients battling Huntington's disease

Allen Institute for Brain Science leads international effort to advance analysis of single neurons

Study finds link between neurodegenerative disorders and inflammation

Neuroscientists discover key building block for learning and memory formation

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

One in five college students experiences exploding head syndrome

Rice University study reveals carbon nanotube fibers can provide two-way connection with neurons

UCLA-led team validates first standardized protocol for tracking early signs of Alzheimer's disease

Brain-somatic-activating mutations in MTOR cause focal cortical dysplasia type II

Mexican researcher close to finding a cure for Parkinson's disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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