Antiviral Drug News and Research

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Viroporins, membrane-permeabilizing proteins of the poliomyelitis virus

A research team from the Universidad Autonoma de Madrid directed by Professor Luís Carrasco has published new discoveries concerning the membrane permeabilizing proteins of the polio virus.

16 Jan 2008

Mouse model shows potential efficacy of HIV prevention strategy

A new kind of laboratory mouse can be used to test the efficacy of much-needed methods to prevent transmission of HIV, the virus that causes AIDS, according to research by J. Victor Garcia and colleagues at the University of Texas Southwestern Medical Center in Dallas.

15 Jan 2008

Anti-retrovirals given daily before and after exposure to HIV prevent vaginal transmission AIDS virus

Prescription drugs now used to treat human immunodeficiency virus infection in adults may prevent the vaginal transmission of HIV, researchers at UT Southwestern Medical Center have found.

15 Jan 2008

Seasonal flu levels trigger use of antiviral drugs

The Health Protection Agency has confirmed that the rate at which influenza viruses are now circulating in England has reached the point which triggers the use of antiviral drugs.

11 Jan 2008

Genomic screen identifies 273 human proteins required for HIV propagation

In some ways, HIV resembles a minimalist painter, using a few basic components to achieve dramatic effects.

11 Jan 2008

Confirmed H5N1 avian influenza in wild swans in Dorset

The Department for the Environment Food and Rural Affairs (Defra) has today confirmed highly pathogenic H5N1 avian influenza among swans in the Chesil Beach area in Dorset .

11 Jan 2008

Potential alternative to the existing smallpox vaccine

University of California, Irvine infectious disease researchers have shown the effectiveness of a potential alternative to the existing smallpox vaccine that can replace the current biodefense stockpile for this lethal virus.

8 Jan 2008

Cases of meningitis caused by herpes simplex virus set to rise

Viral meningitis is common, but many cases go unreported, say researchers in this week's BMJ.

4 Jan 2008

Drug effective for hepatitis C patients with low platelets

For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease.

2 Jan 2008

Controlling lupus - new drug targets found

Investigators at Hospital for Special Surgery have identified two new targets for drugs aimed at controlling lupus.

17 Dec 2007

Crimean Congo hemorrhagic fever virus strips away immune system's defensive measures

When the alert goes out that a virus has invaded the body, cells that have yet to be attacked prepare by "armoring" themselves for combat, attaching specific antiviral molecules to many of their own proteins to help resist the invader.

13 Dec 2007

Treating patients with psychiatric disorders for hepatitis C

People with severe mental illnesses are far more likely to be infected with Hepatitis C virus compared to the general population, however, they often do not get treatment for their liver disease because current antiviral therapies have known psychiatric side effects.

4 Dec 2007

New drug, eltrombopag boosts platelets in hepatitis C patients

It's not a cure, but this may be some of the best news patients infected with the hepatitis C virus (HCV) have heard in a long time: A new drug, eltrombopag, appears to be effective in boosting low platelet counts, one of the major reasons why patients can't endure antiviral treatments.

29 Nov 2007

Simple measures such as hand washing better than drugs in dealing with flu viruses

Scientists say using physical barriers, such as regular hand washing and wearing masks, gloves and gowns, may be far more effective than drugs to prevent the spread of respiratory viruses such as influenza and SARS.

27 Nov 2007

HIV in Thailand appears more deadly

Two studies led by researchers at the Johns Hopkins Bloomberg School of Public Health found that people infected with HIV in Thailand die from the disease significantly sooner than those with HIV living in other parts of the world.

27 Nov 2007

Physical barriers may be more effective than drugs to prevent pandemics

Physical barriers, such as regular handwashing and wearing masks, gloves and gowns may be more effective than drugs to prevent the spread of respiratory viruses like influenza and SARS, concludes a study published on bmj.com.

27 Nov 2007

Brits gear up for pandemic while FDA warns about flu jabs side-effects

The British government says it plans to double its stockpile of antiviral drugs such as Tamiflu to cope with the possibility of a flu pandemic.

26 Nov 2007

Family doctors and patients with herpes are poorly informed about the viral infection

Family doctors and patients with herpes are poorly informed about the viral infection, indicate the results of an online survey, published ahead of print in the journal Sexually Transmitted Infections .

22 Nov 2007

Novel proposal to overcome the virus sharing impasse

In light of the importance of virus monitoring for pandemic influenza preparedness and response, Indonesia's refusal to share samples of avian flu (H5N1) virus with the WHO for most of 2007 is "distressing and potentially dangerous for global public health," say two leading global health experts in an essay in this week's PLoS Medicine.

21 Nov 2007

Tamiflu significantly reduces illness severity and duration in children one year and older

...particularly if given within 24 hours of symptom onset, according to new data presented at the World Society for Pediatric Infectious Disease (WISPID) meeting in Bangkok 15-18 November.

16 Nov 2007