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New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

Russian researchers have developed a strategy to create a cheap and rapid COVID-19 test based on isothermal amplification. According to their publication in Applied Biochemistry and Microbiology, use of this strategy will make it possible to create universal test systems for any of the COVID-19 variants.

29 Dec 2021

New techniques enable visualization of DNA repair machinery in detail

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as cancer.

29 Dec 2021

Combination of rifampicin and resveratrol helps stop dementia, finds study

Dementia is thought to occur when proteins called amyloid-β, tau, and α-synuclein accumulate in the brain and form oligomers. A research group from the Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, had previously shown in a study using mice that the antibiotic rifampicin removes oligomers from the brain and improves cognitive function.

29 Dec 2021

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

COVID-19 vaccination of expectant mothers elicits levels of antibodies to the SARS-CoV-2 outer "spike" protein at the time of delivery that don't vary dramatically with the timing of vaccination during pregnancy and thus don't justify delaying vaccination, according to a study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

28 Dec 2021

Estimating the epidemic potential of SARS-CoV-2 Omicron variant in South Korea

Researchers in South Korea and France have conducted an analysis on individuals infected with Omicron variant (B.1.1.529) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to estimate the epidemic potential and long-term prospects of this virus in circulation. They have found that the basic reproduction number (R0) for this variant is 1.90, while the mean serial interval is 2.22 days.

28 Dec 2021

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants. These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate.

28 Dec 2021

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Scientists at the La Jolla Institute for Immunology have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.

24 Dec 2021

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

A new study from Columbia researchers, in collaboration with scientists at the University of Hong Kong, adds more evidence that the omicron variant can evade the immune protection conferred by vaccines and natural infection and suggests the need for new vaccines and treatments that anticipate how the virus may soon evolve.

24 Dec 2021

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

The Alpha variant of SARS-CoV-2 - the first "variant of concern" - evolved mutations that allowed it to more efficiently suppress the immune system's early response to infection, according to a new study led by scientists at the University of California, San Francisco's Quantitative Biosciences Institute and University College London.

24 Dec 2021

Ad5-nCoV vaccine safe and effective against symptomatic, severe COVID-19, trials shows

One dose of Ad5-nCoV (Convidecia), a COVID-19 vaccine developed in China, is 57.5% effective against symptomatic COVID-19 and 91.7% effective against severe COVID-19 disease beginning 28 days postvaccination, according to a phase 3 randomized controlled trial published in The Lancet.

23 Dec 2021

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

An interdisciplinary research team from the University of Göttingen and Hannover Medical School (MHH) has detected significant changes in the heart muscle tissue of people who died from Covid-19.

23 Dec 2021

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

23 Dec 2021

CDC investigates Listeria outbreaks linked to packaged salads

CDC is currently investigating two separate Listeria outbreaks, both of which are linked to packaged salads. One outbreak is linked to packaged salads produced by Fresh Express.

23 Dec 2021

Study may lead to effective strategies for rehabilitation of children with arthrogryposis

HSE academics joined researchers from the Turner Scientific Research Institute for Children's Orthopaedics to study how the brains of children with arthrogryposis control elbow flexion after muscle transplantation.

23 Dec 2021

Coinfection of SARS-CoV-2 and human rhinovirus associated with more severe health outcomes

Researchers discuss the incidence and effect of coinfections with SARS-CoV-2 and human rhinovirus.

23 Dec 2021

Fiber-rich diet may help some melanoma patients to respond to immunotherapy

A diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment by influencing the gut microbiome, according to a new study led by researchers at the Center for Cancer Research at the National Cancer Institute, part of the National Institutes of Health, and the University of Texas MD Anderson Cancer Center.

23 Dec 2021

Mapping access to HIV care

In this interview, we speak to Professor Diego Cuadros about his latest research in which he mapped individuals' access to HIV care in Africa.

23 Dec 2021

The transmission dynamics of SARS-CoV2 Omicron variant

In a recent study posted to the medRxiv* preprint server, researchers developed a coronavirus disease (COVID-19) model-inference system in South Africa to determine transmission dynamics and immune evasion associated with severe acute respiratory syndrome-associated coronavirus disease (SARS-CoV-2) Omicron variant.

22 Dec 2021

Scientists develop methods to quantify the transmissibility of new COVID-19 variants

As the discovery of the new omicron variant illustrates, new COVID-19 variants will continue to regularly emerge.

22 Dec 2021

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5.5 million to develop new treatments for two types of devastating parasitic infections common in sub-Saharan Africa and Central and South America: river blindness and intestinal worm infections.

22 Dec 2021

Laboratory News and Research

New strategy to create a cheap and rapid COVID-19 test based on isothermal amplification

New techniques enable visualization of DNA repair machinery in detail

Combination of rifampicin and resveratrol helps stop dementia, finds study

Pregnant women should not delay COVID-19 vaccination until late pregnancy, study suggests

Estimating the epidemic potential of SARS-CoV-2 Omicron variant in South Korea

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Omicron variant of SARS-CoV-2 manifests striking antibody evasion

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

Ad5-nCoV vaccine safe and effective against symptomatic, severe COVID-19, trials shows

X-ray imaging of cardiac tissue reveals the impact of Covid-19 on the heart

Researchers identify a key influenza epitope that can targeted for developing universal vaccines

CDC investigates Listeria outbreaks linked to packaged salads

Study may lead to effective strategies for rehabilitation of children with arthrogryposis

Coinfection of SARS-CoV-2 and human rhinovirus associated with more severe health outcomes

Fiber-rich diet may help some melanoma patients to respond to immunotherapy

Mapping access to HIV care

The transmission dynamics of SARS-CoV2 Omicron variant

Scientists develop methods to quantify the transmissibility of new COVID-19 variants

Researchers receive NIH grants to develop new treatments for neglected tropical diseases

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