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Study: Slow walkers have higher risk of contracting severe COVID-19

SLOW walkers are almost four times more likely to die from COVID-19, and have over twice the risk of contracting a severe version of the virus, according to a team of researchers from the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre led by Professor Tom Yates at the University of Leicester.

16 Mar 2021

Study explores how SARS-CoV-2 mutations produce antibody resistance and enhanced transmissibility

An interesting new study deals with the effects of the natural mutations in the spike antigen of the SARS-CoV-2, the pathogen that is responsible for the ongoing coronavirus disease pandemic.

16 Mar 2021

High-strength nicotine e-cigarettes can help adults with schizophrenia quit smoking

A new study in Nicotine & Tobacco Research, published by Oxford University Press, finds that the use of high-strength nicotine e-cigarettes can help adults with schizophrenia spectrum disorders quit smoking.

16 Mar 2021

COVID-19 stay-at-home orders associated with lower rate of preterm births in Tennessee

Statewide stay-at-home orders put in place as Tennessee fought to control the spread of coronavirus last March were associated with a 14% lower rate of preterm birth, according to a research letter published today in JAMA Pediatrics.

15 Mar 2021

SARS-CoV-2 UK variant could be more lethal than others

A new study has assessed the mortality risk of patients infected with the newly emerged UK variant (Lineage B.1.1.7) of SARS-CoV-2. The findings reveal that compared to the previously circulating SARS-CoV-2 variants, the UK variant significantly increases the risk of mortality in a relatively low-risk community population.

15 Mar 2021

Which biomarkers can help predict severe COVID-19?

The ability to detect potentially fatal illness early on in the course of the disease would enable a swift prioritization of these high-risk individuals for treatment. A new preprint on the medRxiv* server presents an array of biomarkers that may help achieve this laudable goal.

15 Mar 2021

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

In a recent bioRxiv preprint research paper, Botond Z. Igyártó and colleagues from Thomas Jefferson University demonstrated the inflammatory nature of the lipid nanoparticles (LNPs).

15 Mar 2021

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

In a methodologically trailblazing paper published in the journal Nature Genetics, a team of Belgian scientists uncovered an assembly of coronavirus host factors that may be exploited to develop drugs against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also potentially forthcoming zoonotic coronaviruses.

14 Mar 2021

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

A recent study, currently available on the bioRxiv preprint server, indicates that a pair of dual-action monoclonal antibodies derived from an original 2003 SARS survivors could play an important role in the fight against coronavirus disease 2019 (COVID-19) due to their broadly neutralizing activity and the engagement of the immune system via effector function capabilities.

14 Mar 2021

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Mantle cell lymphoma is a malignant disease in which intensive treatment can prolong life. In a new study, scientists from Uppsala University and other Swedish universities show that people with mantle cell lymphoma who were unmarried, and those who had low educational attainment, were less often treated with a stem-cell transplantation, which may result in poorer survival.

13 Mar 2021

Overexpression of signaling protein in heart associated with poor survival after heart attack

About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.

13 Mar 2021

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor.

11 Mar 2021

Early tracheotomy shortens ICU stay and lowers risk of ventilator-associated pneumonia

Surgically opening the windpipe, or trachea, within the first seven days of the start of mechanical ventilation decreases the time patients spend on ventilators, shortens their ICU stay and lowers their risk of ventilator-associated pneumonia, according to a systematic review published Thursday (March 11) in JAMA Otolaryngology-Head & Neck Surgery.

11 Mar 2021

Study finds limited association between vitamin D and improved COVID-19 outcomes

New research shows a lack of an association between Vitamin D deficiency and the number of COVID-19 cases, recoveries, or mortality rates in European countries.

11 Mar 2021

Study assesses COVID-19 policy differences between GOP- and Democrat-led states

The per-capita rates of new COVID-19 cases and COVID-19 deaths were higher in states with Democrat governors in the first months of the pandemic last year, but became much higher in states with Republican governors by mid-summer and through 2020, possibly reflecting COVID-19 policy differences between GOP- and Democrat-led states, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Medical University of South Carolina.

10 Mar 2021

Study examines central nervous system imaging manifestations of COVID-19 in children

While neurological complications of COVID-19 in children are rare, in contrast to adults, an international expert review of positive neuroimaging findings in children with acute and post-infectious COVID-19 found that the most common abnormalities resembled immune-mediated patterns of disease involving the brain, spine, and nerves.

10 Mar 2021

Elderly patients at greater risk of dying from hip surgery during busy periods

Hip fractures are serious, especially for the elderly. The operation can be a great strain, and 13 per cent of patients over the age of 70 do not survive 60 days after the fracture.

10 Mar 2021

B.1.1.7 variant raises the risk of death from COVID-19

Variant B.1.1.7 of COVID-19 associated with a significantly higher mortality rate, research shows

10 Mar 2021

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

A new study adds to the sum of knowledge around this issue, showing a highly synchronized and rapid development of an antibody response in breast milk and serum, which reached stable levels around two weeks after the second dose of the vaccine was administered.

10 Mar 2021

Researchers discover new COVID-19 variants in three South African provinces

Variants of the coronavirus are appearing in different parts of the world, many of them spreading with alarming speed.

10 Mar 2021

Mortality News and Research

Study: Slow walkers have higher risk of contracting severe COVID-19

Study explores how SARS-CoV-2 mutations produce antibody resistance and enhanced transmissibility

High-strength nicotine e-cigarettes can help adults with schizophrenia quit smoking

COVID-19 stay-at-home orders associated with lower rate of preterm births in Tennessee

SARS-CoV-2 UK variant could be more lethal than others

Which biomarkers can help predict severe COVID-19?

Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

Less-educated, unmarried patients less likely to undergo a transplant for mantle cell lymphoma

Overexpression of signaling protein in heart associated with poor survival after heart attack

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

Early tracheotomy shortens ICU stay and lowers risk of ventilator-associated pneumonia

Study finds limited association between vitamin D and improved COVID-19 outcomes

Study assesses COVID-19 policy differences between GOP- and Democrat-led states

Study examines central nervous system imaging manifestations of COVID-19 in children

Elderly patients at greater risk of dying from hip surgery during busy periods

B.1.1.7 variant raises the risk of death from COVID-19

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

Researchers discover new COVID-19 variants in three South African provinces

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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