Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Refusal of medical and surgical interventions common among chronically ill elderly

Chronically ill older persons frequently refuse medical and surgical interventions recommended by their physicians, according to a recent study by Yale School of Medicine researchers.

9 Aug 2007

Voluntary exercise induces sex-specific physiological cardiac remodeling

While cardiovascular disease occurs in both men and women, it does not affect them in the same way.

9 Aug 2007

Potential new biomarker for heart failure also strongly predicts risk of death

A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes.

7 Aug 2007

New device to treat chronic congestive heart failure

As part of a 40-site national trial, researchers at UT Southwestern Medical Center are studying a new medical device designed to treat patients with chronic congestive heart failure.

3 Aug 2007

Study compares specialty orthopedic and general hospitals

Specialty orthopedic hospitals serve a healthier population of Medicare patients compared to general hospitals, according to a new study by investigators at the University of Iowa and Department of Veterans Affairs (VA) Iowa City Health Care System.

3 Aug 2007

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Avandia too risky says expert

One of the members of the advisory panel set up to discuss the future of the diabetes pill Avandia says it should be removed from the market because it is too risky and offers no advantage over other alternatives.

30 Jul 2007

Thiazolinediones increase risk of heart failure

A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis by researchers at Wake Forest University School of Medicine and colleagues.

27 Jul 2007

Court rules in favor of Sandoz on Toprol Xl patent

Sandoz was pleased to learn this week that the U.S. Court of Appeals in St. Louis has affirmed a summary judgment by U.S. District Judge Rodney Sippel invalidating patent protection on Toprol XL(R), a beta blocker used to treat angina, heart failure, and high blood pressure.

26 Jul 2007

Metformin gets top grade for diabetes

A type 2 diabetes drug taken orally and in widespread use for more than a decade has been found to have distinct advantages over nine other, mostly newer medications used to control the chronic disease, according to a study by researchers at Johns Hopkins.

26 Jul 2007

Low literacy can shorten life

Not being able to read doesn't just make it harder to navigate each day. Low literacy impairs people's ability to obtain critical information about their health and can dramatically shorten their lives.

24 Jul 2007

Initiative to improve heart failure care at nation's hospitals makes major gains

A national initiative designed to improve heart-failure patient care in hospitals proved effective at increasing hospital adherence to key quality-of-care performance measures and reducing the length of hospital stays for patients.

24 Jul 2007

Being elderly and illiterate means a significantly higher mortality rate

Researchers in the U.S. have found that being elderly and being unable to read and understand basic health information is a bad combination.

24 Jul 2007

Web site puts physicians and hospitals under microscope

As health consumers across the country demand better and more detailed information about their physicians and hospitals, Beth Israel Deaconess Medical Center (BIDMC) is stepping up to detail its own performance efforts ranging from the percentage of clinicians who clean their hands to the number of times physicians take the proper steps in treating heart attack patients.

19 Jul 2007

Wearable cardiac telemedicine system

A Bluetooth heart monitor could text your local hospital if you are about to have a heart attack, according to research published today in Inderscience's International Journal of Electronic Healthcare.

18 Jul 2007

Review of Rosiglitazone for type 2 diabetes mellitus

Little evidence supports using rosiglitazone (Avandia) to improve the quality or length of life among adults with diabetes, according to a systematic review of data by German researchers.

18 Jul 2007

Analysis of diabetes drugs

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS Agency for Healthcare Research and Quality.

17 Jul 2007

Inverse relationship between mortality rates and performance in the hospital quality alliance measures

A new study from the Harvard School of Public Health (HSPH) shows that patients who go to hospitals ranked higher according to specific quality measures have a lower chance of dying than patients treated at lower-ranked hospitals.

17 Jul 2007

Venous thromboembolism in the U.S.

Venous thrombosis (VTE), the formation of blood clots in a vein, is a major health problem for hospitalized patients in the United States.

16 Jul 2007

Autophagy may accelerate decompensated heart failure

Autophagy, a normal process by which cells eat their own proteins to provide needed resources to the body in times of stress, may paradoxically cause harm to hearts already weakened by disease, researchers from UT Southwestern Medical Center have found.

9 Jul 2007