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Coordinated efforts reduce colorectal cancer incidence and mortality rates in Kentucky

Twenty years ago, Kentucky had the highest colorectal cancer incidence and mortality rates in the U.S., as well as the second-lowest colorectal cancer screening rate.

20 Mar 2023

COVID-19 patients more likely to develop gastrointestinal disorders

COVID-19 is associated with an increased risk of developing long-term gastrointestinal disorders, including irritable bowel syndrome.

20 Mar 2023

What role does dysbiosis play in Parkinson's disease?

The current study, published in the journal Revue Neurologique, is based on the hypothesis that dysbiosis, or unhealthy variations in the gut and oral microbiota, is a key component of PD pathogenesis.

19 Mar 2023

Detecting tissue-resident memory T cells in solid tumors

In this interview, NewsMedical talks with Cerba Research about in situ multiplex analysis of regulatory and effector T cells in tumors.

16 Mar 2023

Using probiotics to treat depression

Researchers discuss whether probiotics could be used as supplementary or primary therapy to manage major depressive disorder.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Young people also at risk of colorectal cancer

When Nikki Lawson started to experience some pretty disruptive gastrointestinal discomfort at 35, she chalked it up to her food choices.

6 Mar 2023

Government funding to accelerate research in AI healthcare technologies

Tens of thousands of patients across the country could benefit from quicker, earlier diagnoses and more effective treatments for a range of conditions - as the government invests nearly £16 million into pioneering artificial intelligence research (AI).

3 Mar 2023

Studying gut bacteria's role in muscle regeneration and recover

In a surprising discovery, Harvard Medical School researchers have found that a class of regulatory T cells (Tregs) made in the gut play a role in repairing injured muscles and mending damaged livers.

2 Mar 2023

Modifying gut flora before surgery could reduce postoperative complications in colorectal cancer patients

In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients.

1 Mar 2023

New insight on the uptick in colorectal cancer diagnoses and deaths among younger people

For years, colorectal cancer was believed by many to primarily impact older people; however, in recent years, there has been an uptick in colorectal cancer diagnoses and deaths among younger people ranging in age from their mid-20s to late 50s.

28 Feb 2023

High throughput device isolates and classifies metabolically active CTCs

Researchers from the University of Technology Sydney have developed a new device that can detect and analyze cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress.

27 Feb 2023

Experts develop commercial formulation Campto for colorectal cancer

Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer.

25 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Researchers reveal the impact of vibrating capsules in chronic constipation patients

A new study in Gastroenterology aimed to analyze the safety and efficacy of oral administration of the vibrating capsule in chronic constipation patients.

23 Feb 2023

Altering patients’ gut flora could form the basis of a new therapeutic approach for colon cancer

Studies show that certain bacteria may contribute to the development of colorectal cancer by producing toxins that may damage colon cells or cause an accumulation of DNA mutations and/or intestinal inflammation.

22 Feb 2023

Researchers explore Mediterranean diet and its health benefits in managing obesity

A review article published in the journal Experimental Gerontology describes the utility of Mediterranean diet (MedDiet) in the prevention and management of obesity.

22 Feb 2023

How the human gut microbiota is shaped by diet

A new study in the journal Best Practice & Research Clinical Gastroenterology aimed to summarize the impact of specific nutrients as well as diets on the gut microbiota as well as the future perspectives of using diet as a therapeutic microbiome modulator.

20 Feb 2023