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Integrated cellular map of heart cells unlocks cardiac fibrosis process

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

21 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

Pacific Northwest Research Institute uncovers hidden DNA mechanisms of rare genetic diseases

Researchers at the Pacific Northwest Research Institute (PNRI) and collaborating institutions have made a groundbreaking discovery that could significantly advance our understanding of genomic disorders.

21 Jun 2024

How random gene activity shapes lifespan in C. elegans

Why do some people live for longer than others? The genes in our DNA sequence are important, helping avoid disease or maintain general health, but differences in our genome sequence alone explain less than 30% of the natural variance of human life expectancy.

21 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Researchers identify genetic loci associated with lifetime and frequency of cannabis use.

21 Jun 2024

How micro- and nanoplastics may worsen non-communicable diseases

Researchers review and assess the potential exacerbation of non-communicable diseases by micro- and nanoplastics.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Artificial variants of Withanolides act highly specifically against leukemia cells

Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells.

21 Jun 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Researchers compared the effects of energy-restricted (ER) dietary patterns with nuts or without on body composition, weight, and glycemic management.

21 Jun 2024

Ohio State study unveils white blood cells' role in nerve fiber regeneration

In a new study, neuroscience researchers at The Ohio State University have discovered a special type of human white blood cell that has the potential to regrow nerve fibers.

20 Jun 2024

Evaluation of serum tumor markers as adjuncts in NSCLC management

A new research paper was published in Oncotarget's Volume 15 on June 13, 2024, entitled, "Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management."

20 Jun 2024

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

This study is led by Professor Junnian Zheng and Ming Shi from the Cancer Institute of Xuzhou Medical University, together with the team of Professor Guiyun Cui and Wei Zhang from the Affiliated Hospital of Xuzhou Medical University.

20 Jun 2024

Advances in organoids and embryonic models pose no risk to personhood, expert argues

Advances in organoids and embryonic models of human development have the potential to prompt social and existential questions - e.g., what defines human individuality? However, bioethicist Insoo Hyun of Harvard Medical School and the Museum of Science in Boston says that these models have the potential to strengthen rather than weaken the concept of human individuality when considered within the philosophical frameworks of "personhood" and sentience.

20 Jun 2024

Cell News and Research

Integrated cellular map of heart cells unlocks cardiac fibrosis process

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Pacific Northwest Research Institute uncovers hidden DNA mechanisms of rare genetic diseases

How random gene activity shapes lifespan in C. elegans

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

How micro- and nanoplastics may worsen non-communicable diseases

Using deep learning to design synthetic soluble versions of cell membrane proteins

Artificial variants of Withanolides act highly specifically against leukemia cells

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Ohio State study unveils white blood cells' role in nerve fiber regeneration

Evaluation of serum tumor markers as adjuncts in NSCLC management

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

Advances in organoids and embryonic models pose no risk to personhood, expert argues

Combining JAK inhibitors with checkpoint inhibitors improves cancer immunotherapy response

Role of SMIM1 gene in obesity uncovered

WEHI spinout aims to revolutionize the development of cancer drugs

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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