Acute Respiratory Distress Syndrome News and Research

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Implicit licenses clinical stage antibody program from Lilly

Implicit Bioscience Ltd has announced the acquisition of the clinical-stage monoclonal antibody IC14 from Eli Lilly and Company. Implicit has paid an undisclosed consideration combining cash and stock to Lilly. Lilly will also receive a royalty on future IC14 sales.

25 Feb 2009

Mountaineers measure lowest human blood oxygen levels on record

The lowest ever levels of oxygen in humans have been reported in climbers on an expedition led by UCL (University College London) doctors.

7 Jan 2009

Procalcitonin: A valuable predicator for lethal respiratory failure

High levels or persistent elevation of PCT in patients with severe pneumonia usually results in death. According to a study in Respirology published by Wiley-Blackwell, Procalcitonin (PCT) levels in patients are indicative of survival rates, proving to be a valuable prognostic factor of Acute Respiratory Distress Syndrome (ARDS).

22 May 2008

Austrian scientists identify common mechanism underlying acute respiratory disease syndrome

The Spanish flu outbreak of 1918 killed between 30 and 50 million people. In the infected patients, the ultimate cause of death was acute respiratory distress syndrome (ARDS). This fatal condition is a massive reaction of the body during which the lung becomes severely damaged. ARDS can be induced by various bacterial and viral infections, but also by chemical agents.

17 Apr 2008

Change in trauma level designation associated with improved patient survival

Death rates among patients admitted to a Colorado trauma center appeared to decrease after the center's designation was upgraded, according to a report in the January issue of Archives of Surgery, one of the JAMA/Archives journals.

22 Jan 2008

New understanding of Nipah virus

A collaborative team of scientists from the Uniformed Services University of the Health Sciences (USU) here, and the Australian Animal Health Laboratory have demonstrated an important biological feature of the deadly Nipah virus that can infect and kill both animals and humans.

24 Aug 2007

Researchers discover how a protein modulates the inflammatory response in acute respiratory distress syndrome

Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure.

17 Aug 2007

Patients with an alcohol-use disorder are more likely to require mechanical ventilation

More than 300,000 patients receive mechanical ventilation during intensive care per year in the United States, even though the hospital mortality rate for ventilated patients can approach 50 percent.

26 Jun 2007

New hope for spinal cord injury sufferers

Spinal cord injury (SCI) is one of the most significant forms of neurotrauma with major economic and social impact.

17 Apr 2007

Treatments used for SARS no benefit to victims

Researchers have found, following a systematic review of all studies done on the 2003 SARS epidemic, that none of the treatments used to treat patients appear to have worked.

13 Sep 2006

SARS: Systematic review of treatment effects

The SARS virus set alarm bells ringing across the world when it first appeared in 2002, but now a review of the effectiveness of the treatments used against it has found no evidence that any of them worked.

12 Sep 2006

Drug trial fiasco induced immune system overload in patients

The doctors who treated six British men in a trial of a drug in March which went horribly wrong, say they believe the men suffered an immune system overreaction known as a cytokine storm.

15 Aug 2006

Periodic 'deep inflation' helps prevent ventilator-induced lung injury

Ventilation therapy burst into the public consciousness more than 60 years ago with the "iron lung" and the polio epidemic.

26 Jul 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Corticosteroids do not improve survival in patients with late-stage acute respiratory distress syndrome

The study is the first multi-center randomized clinical trial to evaluate the effects of moderate doses of steroids in ARDS patients when treatment is started 7 days or more after the onset of the condition.

20 Apr 2006

Swine disease in China caused toxic shock syndrome

A large and deadly outbreak of Streptococcus suis disease, in Sichuan province in China last year alarmed health officials worldwide and now scientists from the Chinese Academy of Sciences, the Chinese Center for Disease Control and Prevention, and other Chinese institutions have published the first scientific details of the outbreak.

12 Apr 2006