Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Researchers explored probable humoral immune mechanisms related to EBV curtailment, besides neutralization, by a systematic emphasis on antibody fragment crystallizable-functional activities over the course of EBV infections.

9 Sep 2022

Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

8 Sep 2022

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery.

7 Sep 2022

Greater physical activity, lower sedentary time likely to reduce breast cancer risk

Boosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to strengthen proof of causation and published online in the British Journal of Sports Medicine.

7 Sep 2022

Novel skin imaging technology improves the accuracy of basal cell carcinoma diagnosis

A novel imaging technique significantly improves the accuracy of the diagnosis of basal cell carcinoma (BCC) – the most frequent skin cancer – compared to clinical and dermoscopic examinations alone, according to new research being presented at the 31st European Academy of Dermatology and Venereology Congress.

7 Sep 2022

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes -genes that cause cancer when mutated - are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

1 Sep 2022

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer - at an early enough stage that cure is possible.

30 Aug 2022

Breast MRI may help stratify the risk of second breast cancer

Breast tissue features apparent on MRI are linked with future second breast cancer risk in women with a personal history of breast cancer, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA).

30 Aug 2022

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Hepatitis B virus (HBV) infection is global in nature and induces several incredible liver diseases, such as chronic hepatitis B (CHB), cirrhosis of the liver (LC) and hepatocellular carcinoma (HCC). A total of 882,000 patients died of HBV-related liver diseases in 2019.

25 Aug 2022

Chinese researchers identify a new molecular mechanism of NASH pathogenesis

Nonalcoholic steatohepatitis (NASH), characterized by liver steatosis, inflammation and injury, has emerged as one of major causes for end-stage liver disease like hepatocellular carcinoma. However, what drives its progression?

25 Aug 2022

Soft-tissue sarcomas produce a protein that make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.

24 Aug 2022

Celebrating 10 Years of Global Research with Breast Cancer Now Tissue Bank

Breast Cancer Now Tissue Bank have just celebrated 10 years of groundbreaking breast cancer research. We spoke to Professor Louise Jones to find out more about this achievement!

22 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

A new research paper was published in Oncotarget on August 4, 2022, entitled, "Kinase activity profiling in renal cell carcinoma, benign renal tissue and in response to four different tyrosine kinase inhibitors."

17 Aug 2022

Machine learning models can predict posttreatment recurrence in patients with early-stage hepatocellular carcinoma

According to ARRS' American Journal of Roentgenology (AJR), machine learning models applied to presently underutilized imaging features could help construct more reliable criteria for organ allocation and liver transplant eligibility.

17 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Study uncovers how common genetic mutations cause renal cancer

The understanding of the link between common genetic mutations and certain cancers is increasing.

9 Aug 2022

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

Exposure to a synthetic chemical found widely in the environment is linked to non-viral hepatocellular carcinoma, the most common type of liver cancer, according to a new study conducted by researchers from the Keck School of Medicine of USC and published in JHEP Reports.

9 Aug 2022

Carcinoma News and Research

Further Reading

Blocking FNDC5 prevents cancer-induced cachexia in mice

Study identifies new therapeutic target against lung adenocarcinoma

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Triplet therapy slows progression of advanced kidney cancer

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

Greater physical activity, lower sedentary time likely to reduce breast cancer risk

Novel skin imaging technology improves the accuracy of basal cell carcinoma diagnosis

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Breast MRI may help stratify the risk of second breast cancer

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Chinese researchers identify a new molecular mechanism of NASH pathogenesis

Soft-tissue sarcomas produce a protein that make immune cells 'go bad'

Celebrating 10 Years of Global Research with Breast Cancer Now Tissue Bank

Scientists identify new driver for rare type of liver cancer

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

Machine learning models can predict posttreatment recurrence in patients with early-stage hepatocellular carcinoma

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

Study uncovers how common genetic mutations cause renal cancer

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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