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New AI model improves prediction of cancer immunotherapy success

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others.

3 Jul 2026

Experimental drug shields nerve cells from damage caused by ALS

Amyotrophic Lateral Sclerosis, or ALS, received widespread awareness in the summer of 2014 thanks to an Ice Bucket Challenge. Millions of people participated in the challenge, drenching themselves in ice cold water to bring visibility to this devastating neurodegenerative disease and generate charitable donations for research.

3 Jul 2026

Japan aligns human embryo model research with updated ethical oversight

Human embryo models can help researchers study early human development and infertility without relying solely on human embryos.

2 Jul 2026

First-in-class experimental CAR T-cell therapy shows promise against solid tumors

Researchers with the Charbonneau Cancer Institute at the University of Calgary and McMaster University have identified a unique target present on a specific group of solid cancerous tumors.

2 Jul 2026

Psychological stress accelerates immune aging through the gut microbiota

Psychological stress is increasingly recognized as a risk factor for certain health conditions including cardiovascular disease and diabetes, especially when paired with an impaired immune response.

2 Jul 2026

Prenatal high fructose exposure impairs brain development and memory

Nutritional imbalance during pregnancy can have long-lasting effects on the health status and disease susceptibility of the offspring.

2 Jul 2026

Vascular organoids may be an effective treatment for ischemic heart disease

Ischemic heart disease (IHD), also known as coronary artery disease, is a leading cause of death and morbidity in western countries. IHD arises when blood vessels of the heart become clogged, blunting oxygen and nutrient supply to heart muscle cells, which eventually die off, leading to heart attack or heart failure.

2 Jul 2026

New genome editing tool unlocks fungi's hidden drug-producing potential

Researchers have spent decades-and billions of dollars-sequencing animal and crop genomes, but fungi have historically been the forgotten middle child of genomics, only noticed when they're ruining bread or colonizing toes.

2 Jul 2026

Umbilical cord proteins may explain lifelong health effects of low birth weight

Researchers have long sought to discover why babies who weigh less than expected at birth, a condition known as small for gestational age, or SGA, are at higher risk for heart, lung and metabolic diseases as adults.

2 Jul 2026

Tailored drug combinations improve outcomes for treatment-resistant advanced melanoma

A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to tailor drug combinations based on specific tumor biology to improve outcomes for treatment-resistant advanced melanoma.

2 Jul 2026

New high-throughput biological sensors track cellular lipid molecules

Inside every cell are lipid molecules that make up cellular membranes, helping organelles communicate and respond to stress.

2 Jul 2026

Discovery provides key insights into cellular mechanisms underlying female fertility

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these follicles, the oocyte is surrounded by granulosa cells that supply nutrients, signaling molecules, and structural support essential for egg development.

2 Jul 2026

Low-cost B-cell depleting therapy is as effective as standard treatment for multiple sclerosis

A Norwegian Swedish clinical trial published in the New England Journal of Medicine (NEJM) demonstrates that rituximab, a low-cost B-cell depleting therapy, is as effective as ocrelizumab in newly diagnosed relapsing multiple sclerosis (MS).

2 Jul 2026

Targeted therapy doubles progression-free survival in rare bile duct cancer

Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy – including a near doubling of progression-free survival compared to expectations with standard of care – in previously treated patients with advanced NRG1-positive cholangiocarcinoma.

2 Jul 2026

Simple donor message could expand stem cell transplant options

When a patient needs a stem cell transplant, finding a registered donor is only the first step. Some potential donors drop out before confirmatory typing, reducing the pool from which doctors can choose.

2 Jul 2026

Evolutionary noncoding RNAs reveal new targets for cancer therapy

In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have now uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become integrated into ancient cellular pathways that regulate cancer.

1 Jul 2026

Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATRX-mutant gliomas.

1 Jul 2026

Engineered CAR T cells show promise against myeloproliferative neoplasms

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, in new research led by UCL and University of Oxford researchers.

1 Jul 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

Cannabidiol shows preclinical promise for anxiety, depression and cognition

A new meta-analysis suggests that CBD may improve emotional behavior and cognition in animal models, but researchers caution that its clinical benefits still need to be proven in humans.

1 Jul 2026