Cytokine News and Research

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Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Are dysregulated metabolism and inflammation contributing factors to the ongoing symptoms in long-term COVID-19 syndrome patients?

Researchers reported that dysregulation in energy metabolism and inflammation could contribute to long-term COVID-19 syndrome.

19 Jan 2023

New ‘smart patch’ can detect proinflammatory biomarkers of neurodegenerative diseases

A leading Swansea University scientist has developed a new 'smart patch' that can detect proinflammatory biomarkers of neurodegenerative diseases (such as Parkinson's and Alzheimer's) through the use of microneedle technology.

17 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Could drinking tea help manage COVID-19?

Researchers summarized the content of active ingredients in different types of tea, the second most consumed beverage in the world. They also explored the possibility of using tea extracts for coronavirus disease 2019 (COVID-19) prevention and treatment.

17 Jan 2023

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Researchers investigated how age-related T-cell defects impacted the effectiveness of mRNA-based COVID-19 vaccines.

16 Jan 2023

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

In a recent study published in the journal Nature Neuroscience, researchers in Spain described the effectiveness of a modified vaccinia virus Ankara (MVA) vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate in protecting against SARS-CoV-2 infection in the brain using a mouse model.

12 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

Review shows metformin usage to be associated with better COVID-19 outcomes

Researchers reported on the potential association between metformin usage and coronavirus disease 2019 (COVID-19) outcomes.

11 Jan 2023

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom investigated lncRNA (long non-coding ribonucleic acids) expression in coronavirus disease 2019 (COVID-19) T lymphocyte transcriptomes.

10 Jan 2023

Study suggests air pollution is an important independent risk factor for asthma exacerbations in children living in urban areas

A new study reported that moderate levels of outdoor air pollutants, ozone, and fine particulate matter correlated to non-viral asthma attacks in children and adolescents who live in low-income urban areas.

9 Jan 2023

Clinically relevant biomarker strategies in drug development

In this interview, NewsMedical speaks with Dr. Justin Devine and Dr. Nicholas Woudberg about biomarkers, their importance for drug development as well as the potential they have when it comes to machine learning.

From Synexa Life Sciences 9 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

Researchers reveal previously unknown properties of T cells

Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology and an international research team discovered.

5 Jan 2023

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

A recent study published in the journal Circulation examines the immunological picture in this scenario, looking for clues to the etiology of this rare and potentially serious complication.

5 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Cardiac MRI of individuals with acute or post-acute COVID-19

In a recent study published in the Journal of Clinical Ultrasound, researchers in Italy reported cardiac magnetic resonance (CMR) findings in individuals with myocarditis-like syndrome during the acute phase of SARS-CoV-2 infection (AMCovS) and post-acute phase (cPACS).

3 Jan 2023

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

Cytokine News and Research

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Are dysregulated metabolism and inflammation contributing factors to the ongoing symptoms in long-term COVID-19 syndrome patients?

New ‘smart patch’ can detect proinflammatory biomarkers of neurodegenerative diseases

What are the major findings of long COVID research?

Could drinking tea help manage COVID-19?

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Simple method increases the efficacy of T cell therapy by cytokine conjugation

2022: a year in MIS-C research

Review shows metformin usage to be associated with better COVID-19 outcomes

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

Study suggests air pollution is an important independent risk factor for asthma exacerbations in children living in urban areas

Clinically relevant biomarker strategies in drug development

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

Researchers reveal previously unknown properties of T cells

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Cardiac MRI of individuals with acute or post-acute COVID-19

Why do some people develop persistent lung sequelae after severe COVID-19?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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