Interleukin 6 News and Research

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Interleukin-6 (IL-6) is a protein that in humans is encoded by the "IL6" gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* server, researchers in Singapore and the United States demonstrated that intranasal (I.N.) delivery of a mucosal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination triggered a superior T cell response compared to an equivalent dose of antigen delivered by the subcutaneous (S.C.) route.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Brain injury a common consequence of both COVID-19 and influenza

In a recent study published in the journal Brain, researchers reported that brain injury is common in coronavirus disease 2019 (COVID-19) and influenza.

12 Sep 2022

Prenatal exposure to air pollution increases risk of childhood allergic rhinitis and asthma

In a recent study published in the Journal of Allergy and Clinical Immunology, researchers assessed the impact of prenatal exposure to air pollution on immune perturbations.

8 Sep 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Researchers assessed the role of the gut microbiome in human health and disease.

8 Sep 2022

How does SARS-CoV-2 infection and vaccination impact human immune memory?

Researchers review current knowledge regarding the generation of immune memory responses and their durability post-infection and vaccination.

7 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

How does SARS-CoV-2 infection impact fertility in men?

In a recent review published in the journal Endocrines, researchers summarized existing literature findings on the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male reproductive system and fertility.

7 Sep 2022

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

Scientists have described the epidemiology, transmission, clinical features, diagnosis, treatment, and preventive strategies of monkeypox infection among humans.

6 Sep 2022

Review explores the involvement of the endothelium as an important underpinning of long COVID’s pathophysiology

Researchers discussed possible mechanisms and potential treatment methods for endotheliopathy observed in patients with post-acute sequelae of SARS-CoV-2 infection.

6 Sep 2022

Study suggests loss of smell and brain inflammation are independent in COVID-19

Researchers assessed the association between neuroinvasion and anosmia observed during COVID-19.

5 Sep 2022

How does origin impact antiviral immune response?

A new study observed differential antiviral responses in Indian and European individuals.

1 Sep 2022

Immunosuppressive therapies for COVID-19 treatment

In a new study, researchers assessed the impact of baricitinib, netakimab, and tocilizumab against coronavirus disease 2019 (COVID-19).

31 Aug 2022

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Alzheimer's disease (AD) is the most common type of dementia affecting an estimated 6.3 million Americans age 65 and older. Without the development of medical breakthroughs to prevent, treat, slow or cure AD that number could grow to 13.8 million by 2060.

29 Aug 2022

Is there an association between the gut microbiome of people within different countries and the severity of COVID-19?

Researchers explored the complex relationship between the gut microbiome of people in different countries and the observed COVID-19 severity, measured as the hospitalization rate of the corresponding country.

29 Aug 2022

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

Researchers evaluated pregnancy-specific responses to SARS-CoV-2 infection.

29 Aug 2022

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Researchers found that in SARS-CoV-2 maternal infection, the balance between antiviral response and transplacental transfer of humoral and cellular protection relies on maternal IL-6 and IL10.

29 Aug 2022

Interleukin 6 News and Research

Further Reading

Age-related changes in microbiome composition affects brain macrophages

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Pollutant particles in the air trigger lung cancer in non-smokers

Brain injury a common consequence of both COVID-19 and influenza

Prenatal exposure to air pollution increases risk of childhood allergic rhinitis and asthma

Licorice compounds proposed as effective candidates for treatment of COVID-19

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

How does SARS-CoV-2 infection and vaccination impact human immune memory?

How does SARS-CoV-2 affect the male genitourinary system?

How does SARS-CoV-2 infection impact fertility in men?

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

Review explores the involvement of the endothelium as an important underpinning of long COVID’s pathophysiology

Study suggests loss of smell and brain inflammation are independent in COVID-19

How does origin impact antiviral immune response?

Immunosuppressive therapies for COVID-19 treatment

FAU and Tel Aviv researchers receive grant to tackle Alzheimer’s-related mood disorders

Is there an association between the gut microbiome of people within different countries and the severity of COVID-19?

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

How does the maternal immune response balance SARS-CoV-2 antiviral responses with transplacental transfer of protection to the fetus?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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