Lymphoma News and Research

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Lymphoma is cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

A new study published on the preprint server bioRxiv* aimed to investigate the impacts of COVID-19 on people with various illnesses. Specifically, the researchers at the Rockefeller Cancer Institute, and the University of Arkansas for Medical Sciences wanted to see the effects of COVID-19 on patients with cancer and other infectious diseases.

6 Oct 2020

CAR T cell therapy can predict treatment response in patients with large B-cell lymphoma

Researchers at The University of Texas MD Anderson Cancer Center have identified molecular and cellular characteristics of anti-CD19 CAR T cell infusion products associated with how patients with large B-cell lymphoma (LBCL) respond to treatment and develop side effects.

6 Oct 2020

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

The U.S. Food and Drug Administration has granted Fast Track designation to a novel "switchable" CAR-T cell therapy developed by Calibr, a division of Scripps Research, in a move to accelerate the drug development and review process.

1 Oct 2020

Researchers identify a potential target for small cell lung cancer

The cover for issue 39 of Oncotarget features Figure 4, "Apoptosis assay of NRXN1-targeted ADC at IC50 dose calculated by growth inhibition curves," by Yotsumoto, et al. which reported that the authors identified transmembrane proteins overexpressed specifically in SCLC with little or no expression in normal tissues and decided to focus on the cell adhesion molecule neurexin-1.

1 Oct 2020

FDA releases final guidance to improve patient communication about risks of breast implants

Today, the U.S. Food and Drug Administration issued the final guidance, "Breast Implants - Certain Labeling Recommendations to Improve Patient Communication," as part of the agency's effort to help improve the information available to patients and health care professionals about the risks of breast implants.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of new NCCN Clinical Practice Guidelines in Oncology for Pediatric Hodgkin Lymphoma. Hodgkin lymphoma is one of the most curable forms of pediatric cancer, with long-term survival rates of 90% or higher.

28 Sep 2020

Challenges in High Complexity Flow Cytometry

In this interview, Dra. Mª José Marco from the Department of Hematology at Hopsital Dr. Peset talks to News-Medical Life Sciences about high complexity flow cytometry and the challenges they often face.

From Beckman Coulter Life Sciences - Flow Cytometry 24 Sep 2020

NCCN's first patient and caregiver resource focused on childhood leukemia

The National Comprehensive Cancer Network today announced the publication of the organization's first patient and caregiver resource focused on a childhood cancer type.

23 Sep 2020

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives--but an unfortunate consequence of people living longer with HIV is an increased risk of cancer.

22 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

A single-center observational study of more than 1,000 oncological examinations has demonstrated that positron emission tomography/magnetic resonance imaging (PET/MRI) facilitates cancer staging as well as PET/computed tomography (PET/CT) and improves lesion detectability in select cancers, potentially helping to promote fast, efficient local and whole-body staging in one step.

17 Sep 2020

Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

The cover for issue 37 of Oncotarget features Figure 7, "The combination of romidepsin and KU60019 is synergistic in a xenograft model of MCL," by Scotto, et al. which reported that the antiproliferative effect induced by histone deactylase inhibitors is associated with the up-regulated expression of the cyclin-dependent kinase inhibitor p21.

17 Sep 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

Convalescent plasma could be an effective treatment for children with COVID-19

Early findings from researchers at Children's Hospital of Philadelphia (CHOP) show that convalescent plasma appears to be a safe and possibly effective treatment for children with life-threatening cases of COVID-19.

9 Sep 2020

Study explores link between personal use of hair dyes and cancer risk

Studies have indicated that people who dye their hair regularly may have a higher risk of cancer, especially bladder cancer and breast cancer.

3 Sep 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

FDA provides update on adverse events associated with breast implants

Today, the U.S. Food and Drug Administration is providing an update on adverse events reported to the Agency related to breast implants, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and systemic signs and symptoms referred to by patients as breast implant illness (BII), which some patients report after receiving breast implants.

20 Aug 2020

Democratic convention, night 2: Defending the ACA and attacking Trump on pandemic

The second night of the 2020 Democratic National Convention featured a 17-person keynote speech, past presidents, a roll call vote that doubled as a virtual tour of the United States and an emphasis on health care and national security issues.

19 Aug 2020

Study uses a statistical approach to reveal patterns of cancer incidence

QUT researchers have used nationwide cancer mapping statistics to develop a new mathematical model so health professionals can further question patterns relating to the disease.

13 Aug 2020

Lymphoma News and Research

Further Reading

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

CAR T cell therapy can predict treatment response in patients with large B-cell lymphoma

Calibr's novel 'switchable' CAR-T cell therapy granted FDA's Fast Track designation

Researchers identify a potential target for small cell lung cancer

FDA releases final guidance to improve patient communication about risks of breast implants

Researchers decipher how the immune system memorizes pathogens after an infection

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

Challenges in High Complexity Flow Cytometry

NCCN's first patient and caregiver resource focused on childhood leukemia

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

Research uncovers potential cause of neurotoxicity due to immunotherapy

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Convalescent plasma could be an effective treatment for children with COVID-19

Study explores link between personal use of hair dyes and cancer risk

Using engineered off-the-shelf therapeutic T cells to fight cancer

FDA provides update on adverse events associated with breast implants

Democratic convention, night 2: Defending the ACA and attacking Trump on pandemic

Study uses a statistical approach to reveal patterns of cancer incidence

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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