Neurons News and Research

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Researchers examine role of alpha-synuclein in neuronal cells

Alpha-synuclein is a principal component of Lewy bodies and Lewy neurites, which are pathologic hall-marks of Parkinson's disease. Alpha-synuclein is generally considered to play a role in synaptic activity, although its function remains largely unknown.

13 Mar 2014

Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

Alzheimer's disease is the most widespread degenerative neurological disorder in the world. Over five million Americans live with it, and one in three senior citizens will die with the disease or a similar form of dementia. While memory loss is a common symptom of Alzheimer's, other behavioral manifestations - depression, loss of inhibition, delusions, agitation, anxiety, and aggression - can be even more challenging for victims and their families to live with.

12 Mar 2014

Parkinson disease patients with higher CSF experience faster cognitive decline

Counterintuitive Findings Offer New Insights into Parkinson Disease Pathology, According to New Research Published in The American Journal of Pathology

12 Mar 2014

Pretreatment with SSTF prevents cerebral ischemia-reperfusion injury, says study

Focal cerebral ischemia-reperfusion may lead to neuronal loss in the hippocampus, which is regarded as one of the basic pathological mechanisms underlying cognitive impairment.

11 Mar 2014

Trophos' olesoxime shows beneficial effect on maintaining motor function in SMA patients

Trophos today announces that top-line results from a pivotal clinical trial of its lead product candidate olesoxime in spinal muscular atrophy (SMA) show a beneficial effect on the maintenance of motor function in SMA patients. If approved, olesoxime could be the first treatment specifically developed for SMA patients.

10 Mar 2014

Researchers determine affected areas of brain using speech processing tests with aid of fMRT

The brain processes read and heard language differently. This is the key and new finding of a study at the University Department of Radiology and Nuclear Medicine at the MedUni Vienna, unveiled on the eve of the European Radiology Congress in Vienna (6 to 10 March).

10 Mar 2014

National clinical trial to test new avenue for tinnitus treatment

UT Southwestern Medical Center will take part in a national clinical trial to test a device that could provide relief for people suffering from tinnitus, a persistent buzzing or ringing sound in the ears. The device uses nervous system stimuli to rewire parts of the brain, in hopes of significantly reducing or removing tinnitus.

7 Mar 2014

BWH researchers explore newer approaches to treat Alzheimer's disease

A team of Alzheimer's disease (AD) researchers at Brigham and Women's Hospital (BWH) has been able to study the underlying causes of AD and develop assays to test newer approaches to treatment by using stem cells derived from related family members with a genetic predisposition to (AD).

7 Mar 2014

Research to identify exact mechanisms behind preterm birth and fetal brain injury

An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins-led research suggests.

6 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

Plant pigment could prevent damage to nerves linked with childhood form of SMA

The research team have found that a plant pigment called quercetin - present in some fruits, vegetables, herbs and grains - could help to prevent damage to the nerves associated with the childhood form of motor neurone disease, spinal muscular atrophy (SMA).

5 Mar 2014

Researchers unravel function of proteins involved in cell metabolism

UCPs or uncoupling proteins are present in mitochondria, the powerhouse of each cell in the body. The functions of most of the five known UCPs remain mysterious (UCP2-UCP5), whereby only the distinct function for UCP1 has thus far been discovered.

5 Mar 2014

Stem cells from patients offer model, drug-discovery platform for early-onset form of Alzheimer's

Harvard stem cell scientists have successfully converted skins cells from patients with early-onset Alzheimer's into the types of neurons that are affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells. This may also make it possible to develop therapies far more quickly and accurately than before.

5 Mar 2014

New uses of imaging technologies could help scientists uncover brain's mysteries

Combining two imagine technologies, such as MRI for structure and MEG for activity, could provide a new understanding of our how our brain works.

4 Mar 2014

Researchers identify drug using yeast model that reduces levels of toxic protein in brains of AD patients

Using a yeast model of Alzheimer's disease (AD), Whitehead Institute researchers have identified a drug that reduces levels of the toxic protein fragment amyloid-β (Aβ) and prevents at least some of the cellular damage caused when Aβ accumulates in the brains of AD patients.

4 Mar 2014

Scientists monitor inhibitory neurons that link sense of smell with memory and cognition in mice

Odors have a way of connecting us with moments buried deep in our past. Maybe it is a whiff of your grandmother's perfume that transports you back decades. With that single breath, you are suddenly in her living room, listening as the adults banter about politics.

4 Mar 2014

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig's disease, a debilitating neurological disorder that robs people of their motor skills.

4 Mar 2014

Biostatistics provides clues to understanding autism: an interview with Dr Knut M. Wittkowski, The Rockefeller University

The incidence of autism spectrum disorders has increased sharply since it was first described 60 years ago. Today, ASD affects more than 1% of all children in the U.S. and about half of them develop a life-long disability.

3 Mar 2014

Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds developed by scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich directly modulate nerve-cell function, and open new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment.

3 Mar 2014

Research: Beneficial and toxic roles of brain glycogen

In 2007, in an article published in Nature Neuroscience, scientists at the Institute for Research in Biomedicine (IRB Barcelona) headed by Joan Guinovart, an authority on glycogen metabolism, reported that in Lafora Disease (LD), a rare and fatal neurodegenerative condition that affects adolescents, neurons die as a result of the accumulation of glycogen-chains of glucose.

3 Mar 2014

Neurons News and Research

Researchers examine role of alpha-synuclein in neuronal cells

Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

Parkinson disease patients with higher CSF experience faster cognitive decline

Pretreatment with SSTF prevents cerebral ischemia-reperfusion injury, says study

Trophos' olesoxime shows beneficial effect on maintaining motor function in SMA patients

Researchers determine affected areas of brain using speech processing tests with aid of fMRT

National clinical trial to test new avenue for tinnitus treatment

BWH researchers explore newer approaches to treat Alzheimer's disease

Research to identify exact mechanisms behind preterm birth and fetal brain injury

Scientists reveal how a genetic code variation results in devastating brain diseases

Plant pigment could prevent damage to nerves linked with childhood form of SMA

Researchers unravel function of proteins involved in cell metabolism

Stem cells from patients offer model, drug-discovery platform for early-onset form of Alzheimer's

New uses of imaging technologies could help scientists uncover brain's mysteries

Researchers identify drug using yeast model that reduces levels of toxic protein in brains of AD patients

Scientists monitor inhibitory neurons that link sense of smell with memory and cognition in mice

Neuroscientists unlock a piece of puzzle in fight against Lou Gehrig's disease

Biostatistics provides clues to understanding autism: an interview with Dr Knut M. Wittkowski, The Rockefeller University

Photoreactive compounds open new routes to treatment of neurological diseases

Research: Beneficial and toxic roles of brain glycogen

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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