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Penn State researchers sequence bacteria genomes to enhance the early detection of novel pathogens

To enhance the early detection of novel infectious bacteria that could cause outbreaks of infectious disease and public health emergencies, a team of researchers in Penn State's College of Agricultural Sciences will sequence the genomes of 700 Bacilli bacteria - near relatives of the biothreat pathogen that causes anthrax.

8 Oct 2021

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer's disease pathology.

8 Oct 2021

Wyss Center to lead a collaborative project aimed at improving brain cancer treatment

The Wyss Center announced today that it will lead a collaborative project, as part of Wellcome Leap's Delta Tissue Program, to improve understanding of the brain cancer glioblastoma (GBM) and help develop more effective therapies.

8 Oct 2021

NIH grant to benefit researcher's effort in developing a new method for detecting breast cancer

Electrical engineering professor Magda El-Shenawee's effort to develop a more accurate and less-invasive method for detecting breast cancer will benefit from a $424,545 grant from the National Institutes of Health.

8 Oct 2021

Study shows an association between initial SARS-CoV-2 viral load and disease severity

Researchers investigated the utility of initial SARS-CoV-2 viral loads of tests performed at a Public Health testing facility regarding hospital and ICUs admissions and overall survival.

8 Oct 2021

Study reveals the trends in recreational ketamine use and availability in the U.S.

Recreational ketamine use and availability of the drug have increased in recent years, but it remains an uncommon drug used by less than 1 percent of people in the U.S., according to a new study published in the American Journal of Public Health.

7 Oct 2021

Using AI in biology to unravel how cells fight off invaders

Imagine the day when any tissue or organ can be repaired or the replacements personalized to the patient.

7 Oct 2021

Israeli Pfizer COVID vaccine/myocarditis study, 136 cases out of 5 million

A new study, published in the New England Journal of Medicine, aimed to present clinical, epidemiological, and follow-up findings of myocarditis cases diagnosed in temporal proximity to COVID-19 vaccination and explore the possibility of a causal relationship between the two.

7 Oct 2021

Long-term exposure to low concentrations of air pollution may cause many early deaths

Exposure to low concentrations of air pollution, even at levels permitted under federal regulations, may be causing tens of thousands of early deaths each year among elderly people and other vulnerable groups in the U.S., according to a large national study from Harvard T.H. Chan School of Public Health.

7 Oct 2021

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

Looking for ways to image the human brain for the earliest signs of aging and cognitive decline, Johns Hopkins Medicine researchers recently identified a pattern that links the accumulation of amyloid beta (Aβ) proteins (associated with cognitive decline later in life) with a reduction of serotonin, the brain chemical that improves mood.

7 Oct 2021

$'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures$

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

In an animal study published Oct. 1, 2021, in the International Journal of Radiation Oncology, Biology and Physics, Johns Hopkins Medicine researchers have provided evidence that treating spinal tumors with "fractionated" radiation therapy — doses given in a series of sessions rather than a single treatment — helps prevent vertebral compression fractures.

7 Oct 2021

Deadly subtype of T-cell lymphoma harbors unique mutations

An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in a specific protein signaling pathway, according to a study published in the journal Blood.

7 Oct 2021

New technology shows great promise for early diagnosis of Alzheimer’s disease

A technology developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) shows great promise for diagnosing Alzheimer's disease before symptoms arise, potentially changing the course of research and treatment for this condition, which affects millions of people worldwide and is estimated to be the sixth leading cause of death in the United States.

7 Oct 2021

Potent extended anti- SARS-CoV-2 effect of titanium dioxide surface coatings

A team of researchers has explored the possibility of coating surfaces with TiO2 as a tool to inactivate SARS-CoV-2.

7 Oct 2021

Quick & Effective Microplate Sealing

Porvair Sciences announce a new range of fast to apply and highly effective microplate adhesive seals for labs that are short on time and may not have access to automated sealing instruments.

7 Oct 2021

Scientists develop a cell-free assay to screen SARS-CoV-2 entry inhibitors

Scientists have developed and validated a cell-free fluorescence assay for the rapid screening of protein inhibitors.

7 Oct 2021

Scientists identify a new method to treat triple-negative breast cancer

A team of clinicians and scientists from the National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH) and A*STAR's Genome Institute of Singapore (GIS) has identified a novel method to treat triple-negative breast cancer (TNBC). They discovered that cancer cells switch between different cell states and are able to change from being less aggressive ('epithelial') to being more aggressive ('mesenchymal'), and vice versa.

7 Oct 2021

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues. The findings appeared on Oct. 6, 2021, in Science Advances.

7 Oct 2021

Tiny bubbles show promise for reducing inflammation

Scientists hope that tiny sacs of material excreted by cells - so-called extracellular vesicles - can be used to deliver drugs inside the body. Researchers at Karolinska Institutet now show that these nano-bubbles can transport protein drugs that reduce inflammation caused by different diseases.

6 Oct 2021

Laboratory News and Research

Penn State researchers sequence bacteria genomes to enhance the early detection of novel pathogens

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

Wyss Center to lead a collaborative project aimed at improving brain cancer treatment

NIH grant to benefit researcher's effort in developing a new method for detecting breast cancer

Study shows an association between initial SARS-CoV-2 viral load and disease severity

Study reveals the trends in recreational ketamine use and availability in the U.S.

Using AI in biology to unravel how cells fight off invaders

Israeli Pfizer COVID vaccine/myocarditis study, 136 cases out of 5 million

Long-term exposure to low concentrations of air pollution may cause many early deaths

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

Deadly subtype of T-cell lymphoma harbors unique mutations

New technology shows great promise for early diagnosis of Alzheimer’s disease

Potent extended anti- SARS-CoV-2 effect of titanium dioxide surface coatings

Quick & Effective Microplate Sealing

Scientists develop a cell-free assay to screen SARS-CoV-2 entry inhibitors

Scientists identify a new method to treat triple-negative breast cancer

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Tiny bubbles show promise for reducing inflammation

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