Antibodies News and Research

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DNA vaccine shows promise for colorectal cancer

For the first time in humans, researchers are testing a combined approach to treating advanced stage colorectal cancer (CRC) that may be life-changing for patients.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Clinical trial begins enrollment to test safety of experimental MERS treatments

Enrollment has begun in an early-stage clinical trial testing the safety of two human monoclonal antibodies (mAbs) designed to treat people infected with Middle East respiratory syndrome coronavirus (MERS-CoV).

18 May 2018

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.

18 May 2018

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia plays a much wider role in the disease than previously thought.

18 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Study finds body temperature as major barrier to potential dengue, Zika vaccine

A major route toward creating effective vaccines against dengue virus and Zika involves the E protein that covers the surface of each viral particle.

18 May 2018

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

Dr. Robert Britton firmly believes every molecule is important. This chemist doesn't want any molecule sitting unused on a laboratory shelf or in a fridge.

18 May 2018

New blood test shows promise for early detection of pancreatic cancer

Pancreatic cancer is expected to become the second deadliest cancer in the United States by 2030. It is tough to cure because it is usually not discovered until it has reached an advanced stage. But a new diagnostic test developed by researchers at UC San Diego shows promise for detecting the disease earlier.

17 May 2018

Study: Social connections may protect black men who have sex with men from acquiring HIV

UCLA-led research suggests that receiving support from friends and acquaintances can help prevent black men who have sex with men from becoming infected with HIV.

17 May 2018

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

MIT researchers develop new versatile plug-and-play diagnostic devices

Researchers at MIT's Little Devices Lab have developed a set of modular blocks that can be put together in different ways to produce diagnostic devices.

17 May 2018

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.

17 May 2018

Researchers discover a new antibody type

Researchers have made a discovery that contradicts previous understanding that an antibody only eliminates a specific subgroup of bacteria.

16 May 2018

Prenatal test to determine child's rhesus factor found to be reliable, but benefit is unclear

If the blood of a pregnant woman is rhesus-negative and the blood of the fetus is rhesus-positive, the woman may develop antibodies, which can cause severe harm to subsequent children in particular.

16 May 2018

Scientists reveal active role of IgG antibodies in severity of anaphylaxis

The most severe allergic reaction, anaphylaxis, is the result of an inappropriate immune reaction following the introduction of a usually harmless antigen into the body.

16 May 2018

Immune system can produce 'universal antibodies' against various microorganisms

Bacteria and other microorganisms display structures from sugar molecules on their surfaces. These sugar structures play an important role for immune defense.

15 May 2018

Depression and anxiety strongly linked with autoimmune thyroiditis, shows study

There is a strong link between depression and anxiety disorders and autoimmune thyroiditis, a chronic thyroid condition affecting approximately 10 percent of the population. Scientists at Friedrich-Alexander-Universität Erlangen-Nürnberg have now proven that special treatment could help many sufferers, especially women.

15 May 2018

Computer models provide valuable insight to structure and function of Ebola, Zika viruses

The viruses that cause Ebola and Zika, daunting diseases that inspire concern at every outbreak, share a strong similarity in how they first infiltrate a host's cells. Through the computer modeling capabilities of Los Alamos National Laboratory, the molecular calisthenics involved in invading a cell are visually documented, an essential step toward vaccine and therapeutic medicine development.

15 May 2018

Study: Antibodies against hemorrhagic fever disarm two viruses of same family

Hemorrhagic fever viruses, so named for their ability to induce massive, and at times fatal, internal bleeding, captured the world's attention during the Ebola outbreak of 2014-2016 in West Africa.

15 May 2018

Antibodies News and Research

DNA vaccine shows promise for colorectal cancer

Scientists identify new drug target to combat chikungunya virus

Clinical trial begins enrollment to test safety of experimental MERS treatments

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Study finds body temperature as major barrier to potential dengue, Zika vaccine

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

New blood test shows promise for early detection of pancreatic cancer

Study: Social connections may protect black men who have sex with men from acquiring HIV

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

MIT researchers develop new versatile plug-and-play diagnostic devices

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Researchers discover a new antibody type

Prenatal test to determine child's rhesus factor found to be reliable, but benefit is unclear

Scientists reveal active role of IgG antibodies in severity of anaphylaxis

Immune system can produce 'universal antibodies' against various microorganisms

Depression and anxiety strongly linked with autoimmune thyroiditis, shows study

Computer models provide valuable insight to structure and function of Ebola, Zika viruses

Study: Antibodies against hemorrhagic fever disarm two viruses of same family

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