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Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

New research indicates that a disruption of brain signals for reward and punishment contributes to increased pain sensitivity, known as hyperalgesia, in fibromyalgia patients. Results published in Arthritis & Rheumatism, a journal of the American College of Rheumatology, suggest that this altered brain processing might contribute to widespread pain and lack of response to opioid therapy in patients with fibromyalgia.

5 Nov 2013

Study in mice may help in the development of more effective treatments for anxiety disorders

Excessive fear can develop after a traumatic experience, leading to anxiety disorders such as post-traumatic stress disorder and phobias. During exposure therapy, an effective and common treatment for anxiety disorders, the patient confronts a fear or memory of a traumatic event in a safe environment, which leads to a gradual loss of fear.

4 Nov 2013

Scientists find surprising degree of variation among genomes of individual neurons

It was once thought that each cell in a person's body possesses the same DNA code and that the particular way the genome is read imparts cell function and defines the individual. For many cell types in our bodies, however, that is an oversimplification.

4 Nov 2013

Researchers identify new way to determine successful surgical outcomes for epilepsy

A discovery from Case Western Reserve and Cleveland Clinic researchers could provide epilepsy patients invaluable advance guidance about their chances to improve symptoms through surgery.

31 Oct 2013

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

Prana Biotechnology, a leading global developer of first-in-class treatments for neurodegenerative disease, has today announced the publication of an article in the peer reviewed Aging Cell showing the effects of PBT2 on neurogenesis and in reversing the memory and learning losses associated with the aging process, in normal (ie non transgenic) old mice.

31 Oct 2013

Scientists identify new toxic entity associated with dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases. The findings are published in the journal Acta Neuropathologica.

31 Oct 2013

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA).

From Cellectricon 31 Oct 2013

Dendrites multiply the brain's computing power

Dendrites, the branch-like projections of neurons, were once thought to be passive wiring in the brain. But now researchers at the University of North Carolina at Chapel Hill have shown that these dendrites do more than relay information from one neuron to the next.

31 Oct 2013

New headpiece can improve brain stimulation technique to treat depression

A brain stimulation technique that is used to treat tough cases of depression could be considerably improved with a new headpiece designed by University of Michigan engineers.

30 Oct 2013

Study: Glucose levels, vascular damage contribute to dementia

High blood-sugar levels, such as those linked with Type 2 diabetes, make beta amyloid protein associated with Alzheimer's disease dramatically more toxic to cells lining blood vessels in the brain, according to a new Tulane University study published in latest issue of the Journal of Alzheimer's Disease.

29 Oct 2013

Serotonin 2C receptors induce fast-acting antidepressant effects in mice

More than 1 in 10 Americans take antidepressants, but these medications can take weeks-and for some patients, months-before they begin to alleviate symptoms. Now, scientists from the University of Chicago have discovered that selectively blocking a serotonin receptor subtype induces fast-acting antidepressant effects in mice, indicating a potential new class of therapeutics for depression. The work was published Oct. 29 in Molecular Psychiatry.

29 Oct 2013

Study shows how wrong levels of protein linked with AD can lead to dangerous blockages in brain cells

Scientists have known for some time that a protein called presenilin plays a role in Alzheimer's disease, and a new study reveals one intriguing way this happens.

29 Oct 2013

Rutgers scientists provide new information about rare genetic childhood disorder

Scientists at Rutgers University studying the cause of a rare childhood disease that leaves children unable to walk by adolescence say new findings may provide clues to understanding more common neurodegenerative diseases like Alzheimer's and Parkinson's and developing better tools to treat them.

28 Oct 2013

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

By the time bone cancer is diagnosed in a pet dog, it is often too late to save the animal's life. Instead, the goal of treatment is to keep the dog as comfortable and free of pain as possible for as long as possible.

25 Oct 2013

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

University of Massachusetts Medical School Assistant Professor of Biochemistry and Molecular Pharmacology Gang Han, PhD, has received a $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Mental Health to develop light activated nanoparticles that can be used to image live brain tissue.

25 Oct 2013

Whitehead Institute scientists identify novel Parkinson's disease drug target

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

25 Oct 2013

Scientists find disparities in regulation of transposons between humans and non-human primate cells

Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells, a type of cell that has the ability to form any other cell or tissue in the body.

24 Oct 2013

Researchers describe why current medications only moderately reduce Fragile X symptoms

When you experience something, neurons in the brain send chemical signals called neurotransmitters across synapses to receptors on other neurons. How well that process unfolds determines how you comprehend the experience and what behaviors might follow. In people with Fragile X syndrome, a third of whom are eventually diagnosed with Autism Spectrum Disorder, that process is severely hindered, leading to intellectual impairments and abnormal behaviors.

24 Oct 2013

New technological approach may help improve stem cell-based neurodegenerative diseases

An international research group has successfully tested the use of a new type of porous material for the efficient delivery of key molecules to transplanted cells derived from stem cells. These results can lead to improvements in the way stem cell-based neurodegenerative diseases are treated.

23 Oct 2013

Promising technique for treating eye disease proves effective in preclinical studies

A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California.

23 Oct 2013

Neurons News and Research

Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

Study in mice may help in the development of more effective treatments for anxiety disorders

Scientists find surprising degree of variation among genomes of individual neurons

Researchers identify new way to determine successful surgical outcomes for epilepsy

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

Scientists identify new toxic entity associated with dementia and motor neuron disease

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Dendrites multiply the brain's computing power

New headpiece can improve brain stimulation technique to treat depression

Study: Glucose levels, vascular damage contribute to dementia

Serotonin 2C receptors induce fast-acting antidepressant effects in mice

Study shows how wrong levels of protein linked with AD can lead to dangerous blockages in brain cells

Rutgers scientists provide new information about rare genetic childhood disorder

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

Whitehead Institute scientists identify novel Parkinson's disease drug target

Scientists find disparities in regulation of transposons between humans and non-human primate cells

Researchers describe why current medications only moderately reduce Fragile X symptoms

New technological approach may help improve stem cell-based neurodegenerative diseases

Promising technique for treating eye disease proves effective in preclinical studies

Neuroscience - Third Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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