Laboratory News and Research

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Optimized strategy for generating male germ-cells from mouse pluripotent stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female.

7 Sep 2021

Cancer immunotherapies could benefit older patients as much as younger people

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

7 Sep 2021

Research uses rodent models to connect the influence of feronomic signals on memory

The work, published recently in Nature Communications, used a model of rodents and managed to connect for the first time the influence of feronomic signals on memory. This will make it possible to explore the deficits of integration of spatial memories and social studies in transgenic models of Alzheimer's disease in the future.

7 Sep 2021

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Scientists from the UK and USA have developed an antifouling nanocomposite-coated multiplexed electrochemical sensor platform that can simultaneously detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and virus-specific antibodies. The platform has shown 100% accuracy in detecting viral RNA and IgG-specific anti-SARS-CoV-2 antibodies. The study is currently available on the medRxiv* preprint server.

6 Sep 2021

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

In a recent study, scientists attempt to understand persistent COVID-19 and its implications in patients with hematologic malignancies.

6 Sep 2021

Researchers uncover a key role for the biological clock in asthma

For hundreds of years, people have observed that asthma severity often worsens in the nighttime. One longstanding question has been to what degree the body's internal circadian clock - as opposed to behaviors, such as sleep and physical activities - contributes to worsening of asthma severity.

6 Sep 2021

Study: 7.8% of young and middle-aged Austrians suffer from pathological insomnia

Chronic insomnia is widespread and leads to generally poor physical and mental health and has a high societal cost. General data on insomnia from Austria, including the help-seeking behaviour of those affected, have been lacking until now.

6 Sep 2021

Mystery deaths of children blamed on insanitary conditions and poor resources in India

While authorities in Uttar Pradesh are narrowing down on dengue as the 'mystery disease' behind the deaths of more than 50 people, mostly children, in the last fortnight, they are not ruling out scrub typhus or other monsoon-related infections.

6 Sep 2021

Reliable Easy-to-Use Evaporator for Academic Labs

BioChromato Inc. reports on the enthusiastic uptake of its Smart Evaporator C1 in academic teaching and research laboratories around the world.

From BioChromato Inc. 6 Sep 2021

Home blood collection device could be used for measuring antibodies against SARS-CoV-2

A device that could make it possible for patients to draw their own blood at home was successfully used to collect blood samples for measuring antibodies against SARS-CoV-2, the virus that causes COVID-19, researchers at the University of Washington School of Medicine in Seattle report.

4 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021

Study uncovers new mechanism for memory transfer between individual roundworms

When an organism encounters a threat in its environment, it is to the species' advantage to warn others of the peril.

4 Sep 2021

Georgia State researcher receives award to investigate the influence of environment on IBD

Dr. Michal Kuczma, a research assistant professor in the Institute for Biomedical Sciences at Georgia State University, has received a three-year, $270,000 Career Development Award from the Crohn's and Colitis Foundation to study environmental influences on gut microbiota, immunity and inflammation.

4 Sep 2021

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target on cancer cells to kill them.

2 Sep 2021

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.

2 Sep 2021

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Stephanie Eisenbarth, MD, PhD, has been named chief of Feinberg's Division of Allergy and Immunology in the Department of Medicine, and director of the newly formed Center for Human Immunobiology.

2 Sep 2021

Risk of COVID-19 transmission from animals to older adults

A new study in the journal GeroScience deals with this aspect of the disease, especially with respect to preventing higher death rates in older adults.

2 Sep 2021

Booster shot of Pfizer COVID-19 vaccine provides additional protection against SARS-CoV-2 infection

A team of scientists from the USA and Israel has recently highlighted the importance of a third booster dose of the Pfizer/BioNTech coronavirus disease 2019 (COVID-19) vaccine in achieving additional protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server.

2 Sep 2021

Study paves the way for developing new treatments to fight gonorrhea superbug

Sexually transmitted infection gonorrhea is on the rise as a major public health burden worldwide, with around 87 million new infections a year largely caused by the superbug Neisseria gonorrhoeae which experts fear will soon be untreatable.

2 Sep 2021

Laboratory News and Research

Optimized strategy for generating male germ-cells from mouse pluripotent stem cells

Cancer immunotherapies could benefit older patients as much as younger people

Research uses rodent models to connect the influence of feronomic signals on memory

Multiplexed electrochemical sensor platform enables simultaneous detection of SARS-CoV-2 RNA and host antibodies

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Researchers uncover a key role for the biological clock in asthma

Study: 7.8% of young and middle-aged Austrians suffer from pathological insomnia

Mystery deaths of children blamed on insanitary conditions and poor resources in India

Reliable Easy-to-Use Evaporator for Academic Labs

Home blood collection device could be used for measuring antibodies against SARS-CoV-2

Scientists identify a critical checkpoint in transcription elongation

Study uncovers new mechanism for memory transfer between individual roundworms

Georgia State researcher receives award to investigate the influence of environment on IBD

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

CAR T cells expressing a natural RNA can activate the body’s own T cells against solid tumors

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

World renowned immunologist named chief of Feinberg's Division of Allergy and Immunology

Risk of COVID-19 transmission from animals to older adults

Booster shot of Pfizer COVID-19 vaccine provides additional protection against SARS-CoV-2 infection

Study paves the way for developing new treatments to fight gonorrhea superbug

A guide to density measurement excellence eBook

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Industry Focus eBook - Cell biology (5th edition)

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