Vascular News and Research

RSS

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Night-time hemodialysis patients may have a greater capacity to repair their hearts and blood vessels compared to those on conventional dialysis three times a week, according to a study in the October issue of the American Journal of Physiology - Renal Physiology, published by the American Physiological Society.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Fever of unknown origin might be a marker of occult cancer

Fever of unknown origin is characterised by a fever of more than 3 weeks’ duration, temperatures of more than 38.3°C and a failure to identify the origin of the fever. Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases.

28 Sep 2005

Time-to-treatment is important to success of angioplasty treatment

An in-depth look at hospitals that reduced treatment delays highlights steps other hospitals could take to provide rapid angioplasty treatment to heart attack patients, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

Flavanols help smokers repair blood vessel function

Phytochemicals known as flavanols, which are found in chocolate, fruits and vegetables, can boost the levels of nitric oxide in the blood of smokers and reverse some of their smoking-related impairment in blood vessel function, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology.

28 Sep 2005

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.

28 Sep 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Benefits of statin therapy identified

The greater the reduction in LDL (lower-density lipoprotein) cholesterol achieved by statin therapy the greater the reduction in incidence of major coronary events, coronary revascularisation and stroke, concludes a meta-analysis published online today by The Lancet.

27 Sep 2005

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Although Alzheimer's disease begins long before symptoms appear, early diagnosis of Alzheimer's has so far been elusive. And given that there is no cure for the disease, benefits of early detection remain questionable.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Israeli scientists report in Human Reproduction that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the laboratory into early embryonic development.

26 Sep 2005

Current state of knowledge and experience with vascular birthmarks

The September/October issue of Archives of Facial Plastic Surgery contains several articles on the current state of knowledge and experience with vascular birthmarks, which are caused by blood vessels that do not form correctly.

20 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Does surgery induce angiogenesis in dormant breast cancer?

Analysis of breast-cancer relapse patterns from two independent databases provides indirect evidence for the theory that surgery to remove the primary tumor may initiate formation of a new blood supply (angiogenesis) in formerly dormant metastases, accounting for a pattern of early relapse in younger women.

12 Sep 2005

HOXA1 is a gene that's been looking for a disorder for a long time

Researchers at Children's Hospital Boston, who specialize in studying the genetics of rare eye-movement disorders, have found a rare genetic syndrome whose implications go far beyond the eye, raising intriguing questions about human cardiovascular and brain development.

12 Sep 2005

Part of largest randomised international trial program ever conducted in atrial fibrillation (AF) discontinued

Study treatments for the ACTIVE W trial of the ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) program have been discontinued due to a significant difference in efficacy, in favour of the standard oral anticoagulation (OAC) over antiplatelet therapy (clopidogrel plus aspirin).

6 Sep 2005

Phase II clinical study of ularitide

The European Society of Cardiology (ESC) today highlighted results of a Phase II clinical study of ularitide, a synthetic form of a natriuretic peptide synthesized in the kidney for patients with acute decompensated congestive heart failure (ADHF).

5 Sep 2005

Metabolic Syndrome, a map of the cardiovascular damage

The metabolic syndrome (MS) is a cluster of metabolic abnormalities with abdominal obesity (increased waist circumference) at its centre. Although all forms of obesity have a negative impact on human health, metabolic syndrome describes a set of particularly adverse biochemical changes accompanying (abdominal) obesity.

5 Sep 2005

Vascular News and Research

Study paves the way for new therapeutic targets which can potentially improve heart disease in patients with end-stage kidney failure

Gleevec's uses might expand even further

Fever of unknown origin might be a marker of occult cancer

Time-to-treatment is important to success of angioplasty treatment

Flavanols help smokers repair blood vessel function

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

The immune mechanisms of atherosclerosis

Benefits of statin therapy identified

Tests of cognitive function are the best way so far to predict whether healthy elderly people will develop Alzheimer's

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Current state of knowledge and experience with vascular birthmarks

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Does surgery induce angiogenesis in dormant breast cancer?

HOXA1 is a gene that's been looking for a disorder for a long time

Part of largest randomised international trial program ever conducted in atrial fibrillation (AF) discontinued

Phase II clinical study of ularitide

Metabolic Syndrome, a map of the cardiovascular damage

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News