Immune Response News and Research

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Scientists uncover mechanism that controls cell death processes

Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.

15 Jul 2013

Antibodies boost immune system to fight childhood cancer, shows study

Researchers in the Antibody and Vaccine Group have developed two monoclonal antibodies (mAbs) called anti-4-1BB and anti-CD40 and investigated a third called anti-CTLA-4. Each of these antibodies binds to a different target molecule in the immune system, potentially heightening the body's own immune response to cancer.

12 Jul 2013

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

University of British Columbia researchers have developed a vaccine that may halt the spread of West Nile Virus among common and endangered bird species.

10 Jul 2013

Cancer immunotherapies promise to be a new tool in fight against cancer

Drugs that direct a cancer patient's immune system to eradicate her or his disease, known as cancer immunotherapies, promise to be a new tool in the fight against cancer. Since the Koch Institute's inception, exploring the close relationship between the immune system and cancer has been one of the Institute's priority research areas.

9 Jul 2013

ERC awards grants to boost research on vaccines

Vaccination has achieved huge success in controlling many devastating infectious diseases. However, there are still many such diseases, or 'pathogens', against which we cannot generate life-long protective immunity.

9 Jul 2013

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

The tyrosine kinase MerTK plays a prominent role in the body's immune response. MerTK signaling helps "calm" the body's first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.

9 Jul 2013

Researcher receives $1.58M NIDCR grant to advance research on link between oral bacteria and fetal death

A new four-year, $1.58 million grant from the National Institute of Dental and Craniofacial Research, will allow a Case Western Reserve University School of Dental Medicine researcher to advance her work linking oral bacteria to fetal death.

9 Jul 2013

Immune response to TB bacterium varies between patients of different ethnic origin

The immune response to the bacterium that causes tuberculosis (TB) varies between patients of different ethnic origin, raising important implications for the development of tests to diagnose and monitor treatment for the disease, according to new research published today in the journal PLOS Pathogens.

5 Jul 2013

Study identifies genomic regions associated with cholera susceptibility

An international research team has used a novel approach to identify genetic factors that appear to influence susceptibility to cholera. The findings by investigators from Massachusetts General Hospital (MGH), the Broad Institute and the International Center for Diarrh-al Disease Research, Bangladesh (ICDDR,B) indicate the importance of pathways involved in regulating water loss in intestinal cells and of the innate immune system in the body's response to the bacteria that causes cholera, which affects from 3 to 5 million people each year and causes more than 100,000 deaths.

4 Jul 2013

GAPVAC aims to develop personalized therapeutic vaccines for cancer

A highly innovative project supported by a €6 million European Union Framework 7 (EU FP7) program grant to develop a novel class of therapeutic cancer vaccines is now under way.

4 Jul 2013

Montreal researchers discover novel research model to study auto-immune diseases

A team of researchers at the IRCM, led by Dr. Javier M. Di Noia in the Immunity and Viral Infections research division, discovered a novel research model for the study of auto-immune diseases. The Montr-al scientists are the first to find a way to separate two important mechanisms that improve the quality of antibodies. This study was featured in a recent issue of The Journal of Immunology.

4 Jul 2013

Research reveals unconventional production of specialized T cells essential for balanced immune system

New findings from St. Jude Children's Research Hospital reveal an unconventional control mechanism involved in the production of specialized T cells that play a critical role in maintaining immune system balance. The research appears in the current online edition of the scientific journal Nature.

4 Jul 2013

Researchers study existence of cross-protection between multiple strains of infectious disease

Using a unique data set spanning 40 years of dengue fever incidence in Thailand, an international team led by biostatistician Nicholas Reich at the University of Massachusetts Amherst has for the first time estimated from data that after an initial dengue infection, a person is protected from infection with other strains for between one and three years.

3 Jul 2013

NIDA grants $3.3M to design vaccine conferring immunity to nicotine

A chemical component present in the nightshade family of plants is one of the world's most tenaciously addictive substances. It is the nicotine contained in tobacco and found in high concentrations in cigarettes. Smoking remains a global scourge; in the U.S. it is the leading source of preventable death.

3 Jul 2013

Alnylam Pharmaceuticals presents new pre-clinical data of ALN-AT3 at ISTH meeting

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data from its RNAi therapeutic program for the treatment of hemophilia and rare bleeding disorders.

2 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

Identification of a protein that appears to play an important role in the immune system's removal of amyloid beta (A-beta) protein from the brain could lead to a new treatment strategy for Alzheimer's disease. The report from researchers at Massachusetts General Hospital (MGH) has been published online in Nature Communications.

2 Jul 2013

Tiny RNA molecules work as powerful regulators of immune response in mammals

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.

1 Jul 2013

Study reports new mechanism that regulates specification of lymphocytes

Scientists at an Academy of Finland Centre of Excellence have discovered a new mechanism regulating the immune response that can leave a person susceptible to autoimmune diseases.

28 Jun 2013

New streamlined method harnesses tumor-infiltrating lymphocytes to improve outcomes

Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells.

26 Jun 2013

Immune Response News and Research

Scientists uncover mechanism that controls cell death processes

Antibodies boost immune system to fight childhood cancer, shows study

UBC researchers develop vaccine to halt spread of West Nile Virus in birds

Cancer immunotherapies promise to be a new tool in fight against cancer

ERC awards grants to boost research on vaccines

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

Researcher receives $1.58M NIDCR grant to advance research on link between oral bacteria and fetal death

Immune response to TB bacterium varies between patients of different ethnic origin

Study identifies genomic regions associated with cholera susceptibility

GAPVAC aims to develop personalized therapeutic vaccines for cancer

Montreal researchers discover novel research model to study auto-immune diseases

Research reveals unconventional production of specialized T cells essential for balanced immune system

Researchers study existence of cross-protection between multiple strains of infectious disease

NIDA grants $3.3M to design vaccine conferring immunity to nicotine

Alnylam Pharmaceuticals presents new pre-clinical data of ALN-AT3 at ISTH meeting

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

Tiny RNA molecules work as powerful regulators of immune response in mammals

Study reports new mechanism that regulates specification of lymphocytes

New streamlined method harnesses tumor-infiltrating lymphocytes to improve outcomes

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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